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SKU:PAE189Hu01

Polyclonal Antibody to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)

Polyclonal Antibody to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)

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UOM
Concentration
Organism species

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

Product No.

PAE189Hu01

Organism Species

Homo sapiens (Human).

Source

Polyclonal antibody preparation

Host

Rabbit

Potency

n/a

Ig Type

IgG

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Label

None

Immunogen

RPE189Hu01-Recombinant Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)

Buffer Formulation

PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Traits

Liquid

Concentration

0.5mg/ml

Organism Species More

Mus musculus (Mouse), Rattus norvegicus (Rat)

Applications

WB; IHC; ICC; IP.

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against PCSK9. It has been selected for its ability to recognize PCSK9 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine

Citations

Biological Trace Element Research

Synergistic Cardioprotective Effects of Combined Chromium Picolinate and Atorvastatin Treatment in Triton X-100-Induced Hyperlipidemia in Rats: Impact on Some Biochemical Markers pubmed:28409410

BASIC RESEARCH IN CARDIOLOGY

Autocrine effects of PCSK9 on cardiomyocytes Pubmed: 33169229

J Transl Med

Multi-omic signatures of atherogenic dyslipidaemia: pre-clinical target identification and validation in humans 33407555

Metabolism

MiR-337-3p lowers serum LDL-C level through targeting PCSK9 in hyperlipidemic mice 33775647

Eur Rev Med Pharmacol Sci

Association of serum proprotein convertase Subtilisin/Kexin Type 9 (PCSK9) level with thyroid function disorders 34533801

Clin Exp Hypertens

Proprotein convertase subtilisin/kexin type 9 is associated with atherosclerosis in patients with Behcet's disease Pubmed:35502687


Catalog No.

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Applications (RESEARCH USE ONLY!)

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