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SKU:PAJ557Hu01
Polyclonal Antibody to Beclin 1 (BECN1)
Polyclonal Antibody to Beclin 1 (BECN1)
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Western blotting: 0.5-3µg/mL
;Immunohistochemistry: 5-30µg/mL
;Immunocytochemistry: 5-30µg/mL
;Optimal working dilutions must be determined by end user.
Product No.
PAJ557Hu01
Organism Species
Homo sapiens (Human).
Source
Polyclonal antibody preparation
Host
Rabbit
Potency
n/a
Ig Type
IgG
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Label
None
Immunogen
RPJ557Hu01-Recombinant Beclin 1 (BECN1)
Buffer Formulation
0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Traits
Liquid
Concentration
0.5mg/ml
Organism Species More
Mus musculus (Mouse), Rattus norvegicus (Rat), Canis familiaris; Canine (Dog), Sus scrofa; Porcine (Pig), Bos taurus; Bovine (Cattle), Ovis aries; Ovine (Sheep)
Applications
WB,IHC
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against BECN1. It has been selected for its ability to recognize BECN1 in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.01-3µg/mL;
Immunohistochemistry: 5-30µg/mL;
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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Magazine |
Citations |
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Rejuvenation Res. |
Can Enhanced Autophagy be Associated with Human Longevity? Serum Levels of the Autophagy Biomarker Beclin-1 are Increased in Healthy Centenarians Pubmed:25307612 |
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J Cosmet Dermatol |
A peel-off facial mask comprising myoinositol and trehalose-loaded liposomes improves adult female acne by reducing local hyperandrogenism and activating autophagy pubmed:28342238 |
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Tumor Biology |
The novel CXCR4 antagonist, PRX177561, reduces tumor cell proliferation and accelerates cancer stem cell differentiation in glioblastoma preclinical models pubmed:28639900 |
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19 |
Beclin1 circulating levels and accelerated ageing markers in COPD DOI: 10.1183/1393003.congress-2017.PA1018 |
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Cell Death & Disease |
Beclin1 circulating levels and accelerated aging markers in COPD Pubmed:29402890 |
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Clinica Chimica Acta |
A novel combined score of biomarkers in sputum may be an indicator for lung cancer: A pilot study Doi: 10.1016/j.cca.2018.09.027 |
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International Journal of Clinical and Experimental Pathology |
Serum concentration of autophagy-related protein 7 is correlated with non-alcoholic fatty liver disease in Chinese adults |
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EXPERIMENTAL AND THERAPEUTIC MEDICINE |
Crosstalk between vitamin D axis, inflammation and host immunity mechanisms: A prospective study 33936265 |
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International Journal for Research in Applied Sciences and Biotechnology |
Inhibition of HepG-2 Cells (Liver Cancer Cell Line) Viability by 3-Hydroxypyridine-2-Carboxaldehyde N (4)-Methylthiosemicarbazone |
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BIOMARKERS OF AUTOPHAGY AND ANTIVIRAL ROLE OF PLACENTA FOR PREDICTING PRETERM DELIVERY IN PATIENTS WITH PRETERM DELIVERY?¡ |
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European Journal of Natural History |
IDENTIFICATION OF FACTORS CONNECTED WITH AUTOPHAGY ACTIVITY UNDER CONDITIONS OF PARTIAL NUTRITIONAL DEPRIVATION IN MEN |
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Catalog No. |
Related products for research use of Homo sapiens (Human) Organism species |
Applications (RESEARCH USE ONLY!) |
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RPJ557Hu01 |
Positive Control; Immunogen; SDS-PAGE; WB. |
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PAJ557Hu01 |
WB,IHC |
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MAJ557Hu21 |
WB; IHC; ICC; IP. |
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MAJ557Hu22 |
WB; IHC; ICC; IP. |
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MAJ557Hu23 |
WB; IHC; ICC; IP. |
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MAJ557Hu24 |
WB; IHC; ICC; IP. |
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MAJ557Hu25 |
WB; IHC; ICC; IP. |
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SEJ557Hu |
Enzyme-linked immunosorbent assay for Antigen Detection. |
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LMJ557Hu |
Magnetic Luminex Assay for Antigen Detection. |
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