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SKU:PAA506Hu01

Polyclonal Antibody to D-Dimer (D2D)

Polyclonal Antibody to D-Dimer (D2D)

Regular price $280.00 USD
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UOM
Concentration
Organism species

Western blotting: 0.5-2µg/mL;1:420-1700
Immunohistochemistry: 5-20µg/mL;1:42-170
Immunocytochemistry: 5-20µg/mL;1:42-170
Optimal working dilutions must be determined by end user.

Product No.

PAA506Hu01

Organism Species

Homo sapiens (Human).

Source

Polyclonal antibody preparation

Host

Rabbit

Potency

n/a

Ig Type

IgG

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Label

None

Immunogen

CPA506Hu21-OVA Conjugated D-Dimer (D2D)

Buffer Formulation

0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Traits

Liquid

Concentration

0.39mg/ml

Organism Species More

n/a

Applications

WB; IHC; ICC; IP.

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against D2D. It has been selected for its ability to recognize D2D in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine

Citations

22

Determinants of the thrombogenic potential of multiwalled carbon nanotubes ScienceDirect: S0142961211004819

Journal of Thrombosis and Haemostasis

Exogenous Activated Protein C Inhibits the Progression of Diabetic Nephropathy Pubmed: 22236035

PLOS ONE

Protective Effect of Curcumin on Pulmonary and Cardiovascular Effects Induced by Repeated Exposure to Diesel Exhaust Particles in Mice PlosOne: Source

Haemetology

Clinical impact of factor V Leiden, prothrombin G20210A, and MTHFR C677T mutations among sickle cell disease patients of Central India Pubmed: 23992124

Journal of Trauma and Acute Care Surgery

Assessment of coagulopathy, endothelial injury, and inflammation after traumatic brain injury and hemorrhage in a porcine model Lww:Source

Journal of Thrombosis and Haemostasis

Protein S exacerbates alcoholic hepatitis by stimulating liver natural killer T cells Pubmed:25399514

Inflammation.?

Systemic and Flap Inflammatory Response Associates with Thrombosis in Flap Venous Crisis Pubmed:25448261

Medical Science Monitor

Impact of β-Adrenoceptor Blockade on Systemic Inflammation and Coagulation Disturbances in Rats with Acute Traumatic Coagulopathy Pubmed:25676919

Blood

Intraperitoneal administration of activated protein C prevents postsurgical adhesion band formation. PubMed: 25575539

Am J Physiol Regul Integr Comp Physiol

Procoagulant and Fibrinolytic Activity after Polytrauma in Rat PubMed: 26632604

hypertension Research

Upregulation of canonical transient receptor potential channel in the pulmonary arterial smooth muscle of a chronic thromboembolic pulmonary hypertension rat model PubMed: 26155749

Molecular Nutrition & Food Research

Trans‐fatty acid promotes thrombus formation in mice by aggravating antithrombogenic endothelial functions via Toll‐like receptors PubMed: 25546502

JCI Insight.

KLF2 and KLF4 control endothelial identity and vascular integrity. pubmed:28239661

The American Society of Anesthesiologists

Activated protein C drives the hyperfibrinolysis of acute traumatic coagulopathy pubmed:27841821

32

Activated TAFI Promotes the Development of Chronic Thromboembolic Pulmonary Hypertension: A Possible Novel Therapeutic Target pubmed:28289017

The American Journal of Pathology

Inhibition of Cell Apoptosis and Amelioration of Pulmonary Fibrosis by Thrombomodulin pubmed:28739343

Atherosclerosis

Low dose of alcohol attenuates pro-atherosclerotic activity of thrombin. pubmed:28923781

28

Lactadherin Promotes Microvesicle Clearance to Prevent Coagulopathy and Improves Survival of Severe TBI Mice pubmed:29162596

Journal of Thrombosis and Thrombolysis

Guided longer pulses from a diagnostic ultrasound and intraclot microbubble enhanced catheter-directed thrombolysis in vivo. pubmed:28417266

Journal of Investigative Surgery

Experimental Evaluation of a New Tissue Factor-Based Topical Hemostat (TT-173) for Treatment of Hepatic Bleeding Pubmed: 30380352

Marine Drugs

The Inhibitory Effect of Protamine on Platelets is Attenuated by Heparin without Inducing Thrombocytopenia in Rodents Pubmed: 31533230

Intensive Care Med Exp

Complement factor D is linked to platelet activation in human and rodent sepsis 34396466

Thromb Res

NLRP3 Inflammasome contributes to endotoxin-induced coagulation Pubmed:35421682

Experimental and Therapeutic Medicine

Construction of a rabbit model with vinorelbine administration via peripherally inserted central catheter and dynamic monitoring of changes in phlebitis and thrombosis Pubmed:35126715


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