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SKU:PAA747Hu01

Polyclonal Antibody to Complement 1q (C1q)

Polyclonal Antibody to Complement 1q (C1q)

Regular price $358.00 USD
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UOM
Concentration
Organism species

Western blotting: 0.5-2µg/mL
;Immunohistochemistry: 5-20µg/mL
;Immunocytochemistry: 5-20µg/mL
;Optimal working dilutions must be determined by end user.

Product No.

PAA747Hu01

Organism Species

Homo sapiens (Human).

Source

Polyclonal antibody preparation

Host

Rabbit

Potency

n/a

Ig Type

IgG

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Label

None

Immunogen

n/a

Buffer Formulation

0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Traits

Liquid

Concentration

0.41mg/ml

Organism Species More

n/a

Applications

WB; IHC; ICC; IP.

If the antibody is used in flow cytometry, please check FCM antibodies

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against C1q. It has been selected for its ability to recognize C1q in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine

Citations

Journal of Clinical Immunology

Complement activation contributes to the injury and outcome of kidney in human anti-glomerular basement membrane disease. PubMed: 22941511

Fish and Shellfish Immunology

Characterization of complement 1q binding protein of tiger shrimp, Penaeus monodon, and its C1q binding activity Pubmed: 23085472

Journal of Neuroimmunology

Acute and prolonged complement activation in the central nervous system during herpes simplex encephalitis Pubmed:27235358

Archives of Gynecology and Obstetrics

The role of complement components C1q, MBL and C1 inhibitor in pathogenesis of endometriosis Pubmed:29572748

Journal of NeuroVirology

Intrathecal complement activation by the classical pathway in tick-borne encephalitis Pubmed: 30850976

PLoS One

Complement activation profile of patients with primary focal segmental glomerulosclerosis Pubmed: 32569286

CELL

Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia 33248023

Chinese Journal of Nephrology, Dialysis & Transplantation

Plasma and urine complement activation products in light chain and heavy chain deposition disease

Journal of Chemical Neuroanatomy

Matrine treatment induced an A2 astrocyte phenotype and protected the blood-brain barrier in CNS autoimmunity 34280490

Neuropsychiatr Dis Treat

Elevated Serum Complement C1q Levels After Traumatic Brain Injury and Its Association with Poor Prognosis Pubmed:35035218


Catalog No.

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