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SKU:PAH339Mu02

Polyclonal Antibody to Periostin (POSTN)

Polyclonal Antibody to Periostin (POSTN)

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UOM
Concentration
Organism species

Western blotting: 0.5-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.

Product No.

PAH339Mu02

Organism Species

Mus musculus (Mouse).

Source

Polyclonal antibody preparation

Host

Rabbit

Potency

n/a

Ig Type

IgG

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Label

None

Immunogen

RPH339Mu02-Recombinant Periostin (POSTN)

Buffer Formulation

0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Traits

Liquid

Concentration

500µg/mL

Organism Species More

Homo sapiens (Human), Rattus norvegicus (Rat)

Applications

WB; IHC; ICC; IP.

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against POSTN. It has been selected for its ability to recognize POSTN in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine

Citations

Blood

Circulating Periostin Is Elevated In Patients With Hemoglobinopathies and Correlates With Bone Mineral Density In Double Heterozygous Sickle-Cell/Beta-Thalassemia Patients; A Novel Marker Of Bone Strength? Bloodjournal: Source

The Journal of Clinical Endocrinology & Metabolism

Serum periostin is associated with fracture risk in postmenopausal women: a 7 years prospective analysis of the OFELY study Pubmed: 24628551

J Clin Endocrinol Metab.

Serum Periostin Is Associated With Fracture Risk in Postmenopausal Women: A 7-Year Prospective Analysis of the OFELY Study Pubmed:24628551

Rheumatology (Oxford).

Circulating periostin levels in patients with AS: association with clinical and radiographic variables, inflammatory markers and molecules involved in bone formation Pubmed:25349442

Journal of Periodontal Research

Assessment of periostin levels in serum and gingival crevicular fluid of patients with periodontal disease Pubmed:25529858

新医学

血清内脂素水平与多囊卵巢综合征的相关性研究 Xinyixue:Source

Osteoarthritis

Serum periostin is associated with prevalent knee osteoarthritis and disease incidence/progression in women: the OFELY study PubMed: 26072384

Endocrine

Serum periostin is a potential biomarker for non-alcoholic fatty liver disease: a case– control study PubMed: 26362060

Blood Cancer Journal

High levels of periostin correlate with increased fracture rate, diffuse MRI pattern, abnormal bone remodeling and advanced disease stage in patients with newly … pubmed:27716740

Metabolism. 

Low periostin levels in adult patients with Langerhans cell histiocytosis are independently associated with the disease activity. pubmed:28521873

Osteoporosis International

Circulating periostin levels increase in association with bone density loss and healing progression during the early phase of hip fracture in Chinese older women pubmed:28382553

Molecular Diagnosis & Therapy

The Utility of Biomarkers in Osteoporosis Management pubmed:28271451

Journal of Bone and Mineral Research

Cortical and trabecular bone microstructure did not recover at weight-bearing skeletal sites and progressively deteriorated at non-weight-bearing sites during the year following International Space Station missions doi:10.1002

Clinical Cases in Mineral and Bone Metabolism

Periostin and sclerostin levels in juvenile Paget's disease pubmed:29263750

Calcified Tissue International

Development of a New Immunoassay for Human Cathepsin K-Generated Periostin Fragments as a Serum Biomarker for Cortical Bone pubmed:28725907

Wiley

Characterization of a sandwich ELISA for the quantification of all human periostin isoforms pubmed:28493527

International Osteoporosis Foundation and National Osteoporosis Foundation

Interaction between LRP5 and periostin gene polymorphisms on serum periostin levels and cortical bone microstructure pubmed:29038835

Bone

Effect of age and gender on serum periostin: Relationship to cortical measures, bone turnover and hormones pubmed:28323143

Clinica Chimica Acta

Association between serum periostin concentrations and outcome after acute spontaneous intracerebral hemorrhage pubmed:28882488

Clinica Chimica Acta

Serum periostin concentrations and outcomes after severe traumatic brain injury pubmed:28668564

Tumor Biology

Predictive and prognostic value of serum periostin in advanced non–small cell lung cancer patients receiving chemotherapy pubmed:28459197

Journal of Bone and Mineral Research

Serum Levels of a Cathepsin-K Generated Periostin Fragment Predict Incident Low-Trauma Fractures in Postmenopausal Women Independently of BMD and FRAX pubmed:28766739


ОСОБЕННОСТИ СОСТОЯНИЯ ЗДОРОВЬЯ НОВОРОЖДЕННЫХ, РОЖДЕННЫХ ОТ МАТЕРЕЙ С БРОНХИАЛЬНОЙ АСТМОЙ 2017; 62:(4)

Endocrine

Circulating periostin in patients with nonalcoholic fatty liver disease. pubmed:27738886

Molecular Medicine Reports

Periostin cross‑reacts with the renin‑angiotensin system during liver fibrosis development pubmed:28849131

The Journal of Biological Chemistry

Toll-like receptor 2 deficiency hyperactivates the FoxO1 transcription factor and induces aging-associated cardiac dysfunction in mice Pubmed:29929978

Calcified Tissue International

The C-Terminal Intact Forms of Periostin (iPTN) Are Surrogate Markers for Osteolytic Lesions in Experimental Breast Cancer Bone Metastasis Pubmed:29916127

Journal of Endocrinological Investigation

Increased serum periostin concentrations are associated with the presence of diabetic retinopathy in patients with type 2 diabetes mellitus Pubmed:29349642

Wiener klinische Wochenschrift

Rheumatoid arthritis in remission

Clinical and Experimental Medicine

Myostatin and other musculoskeletal markers in lung transplant recipients Pubmed: 30317402

Experimental and Clinical Endocrinology & Diabetes

Polycystic Ovary Syndrome is Associated with Elevated Periostin Levels Pubmed: 30372763


ИСПОЛЬЗОВАНИЕ СЫВОРОТОЧНОГО ПЕРИОСТИНА В КАЧЕСТВЕ МАРКЕРА ОБОСТРЕНИЙ АСТМЫ У ДЕТЕЙ

Bone

Tartrate-resistant acid phosphatase 5b, but not periostin, is useful for assessing Paget's disease of bone Pubmed: 31051316

Journal of Clinical Laboratory Analysis

Identification and diagnostic value of pleural fluid periostin and serum periostin of malignant pleural effusions in patients with non–small‐cell lung cancer Pubmed: 31268191

Bone

Serum periostin is associated with cancer mortality but not cancer risk in older home-dwelling men: A 8-year prospective analysis of the STRAMBO study Pubmed: 31812700

FASEB J

Fibronectin rescues aberrant phenotype of endothelial cells lacking either CCM1, CCM2 or CCM3 Pubmed: 32515053

Journal of Reproductive Immunology

Serum and placental periostin levels in women with early pregnancy loss Pubmed: 32460058

Annals of Medical Research

Evaluation of periostin levels in gingival crevicular fluid and peri-implant sulcus fluid in patients with periodontal and peri-implanter disease: A cross-sectional …


Myostatin and Markers of Bone Metabolism in Dermatomyositis

Am J Physiol Heart Circ Physiol

Periostin promotes arterial calcification through PPAR¦Ã-related glucose metabolism reprogramming 33834866

International Journal of Chronic Obstructive Pulmonary Disease

High Blood Eosinophil and YKL-40 Levels, as Well as Low CXCL9 Levels, are Associated with Increased Readmission in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease 33814903

J Bone Oncol

Serum total periostin is an independent marker of overall survival in bone metastases of lung adenocarcinoma 34150488

Rambam Maimonides Med J

The Relationship between Serum Periostin Levels and Neutrophil¨CLymphocyte Ratio with Lesion Localization and Acute Prognosis in Acute Ischemic Stroke 34137680

Rambam Maimonides Medical Journal

First Admission Neutrophil–Lymphocyte Ratio May Indicate Acute Prognosis of Ischemic Stroke 34137680


Catalog No.

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Applications (RESEARCH USE ONLY!)

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Polyclonal Antibody to Periostin (POSTN)

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FITC-Linked Polyclonal Antibody to Periostin (POSTN)

WB; IHC; ICC; IF.

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ELISA Kit for Periostin (POSTN)

Enzyme-linked immunosorbent assay for Antigen Detection.

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Magnetic Luminex Assay Kit for Periostin (POSTN) ,etc.

Magnetic Luminex Assay for Antigen Detection.

 

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