Cloud-clone
SKU:PAA889Mu02
Polyclonal Antibody to Renin (REN)
Polyclonal Antibody to Renin (REN)
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Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.
Product No.
PAA889Mu02
Organism Species
Mus musculus (Mouse).
Source
Polyclonal antibody preparation
Host
Rabbit
Potency
n/a
Ig Type
IgG
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Label
None
Immunogen
RPA889Mu02-Recombinant Renin (REN)
Buffer Formulation
0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Traits
Liquid
Concentration
500µg/mL
Organism Species More
Homo sapiens (Human)
Applications
WB,IHC
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against REN. It has been selected for its ability to recognize REN in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.01-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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Magazine |
Citations |
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Hypertension |
Prenatal overexposure to glucocorticoids programs renal 11β-hydroxysteroid dehydrogenase type 2 expression and salt-sensitive hypertension in the rat PubMed: 21045727 |
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The Journal of Physiology |
Recombinant human erythropoietin in humans down-regulates proximal renal tubular reabsorption and causes a fall in glomerular filtration rate Physoc: 194241 |
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The Journal of Physiology |
Erythropoietin down‐regulates proximal renal tubular reabsorption and causes a fall in glomerular filtration rate in humans PubMed: 20724370 |
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Pathobiology |
Anti-Angiotensin and Hypoglycemic Treatments Suppress Liver Metastasis of Colon Cancer Cells Karger: 000330169 |
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Journal of Cardiovascular Pharmacology |
The Angiotensin Receptor Blocker, Azilsartan Medoxomil (TAK-491), Suppresses Vascular Wall Expression of Plasminogen Activator Inhibitor Type-I Protein Potentially Facilitating the Stabilization of Atherosclerotic Plaques LWW: 08000 |
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Kidney International |
Multiple and large simple renal cysts are associated with prehypertension and hypertension. Pubmed: 23389415 |
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Human Physiology |
Estimation of the parameters of the renin-angiotensin-aldosterone system, water-electrolyte metabolism, and endothelial function in newborns of women with chronic hypertension Springer:Source |
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Journal of Pharmacological Sciences |
Organ-Specific Activation of the Gastric Branch of the Efferent Vagus Nerve by Ghrelin in Urethane-Anesthetized Rats Pubmed:24366191 |
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Liver International |
VSL#3 probiotic treatment decreases bacterial translocation in rats with carbon tetrachloride-induced cirrhosis Pubmed:24750552 |
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Gynecological Endocrinology |
Immunological and hemostasiological disorders in women with ovarian hyperstimulation syndrome Pubmed:25200828 |
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Oxidative Medicine and Cellular Longevity |
Age-Associated Changes in the Vascular Renin-Angiotensin System in Mice Pubmed:27200147 |
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PLoS One |
Ablation of Potassium-Chloride Cotransporter Type 3 (Kcc3) in Mouse Causes Multiple Cardiovascular Defects and Isosmotic Polyuria Pubmed:27166674 |
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PLOS ONE |
Reduced Expression of the Extracellular Calcium-Sensing Receptor (CaSR) Is Associated withActivation of the Renin-Angiotensin System (RAS) to Promote Vascular Remodeling in the Pathogenesis of Essential Hypertension. pubmed:27391973 |
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Heart Lung Circ. |
Efficacy and Safety of Renal Sympathetic Denervation on Dogs with Pressure Overload-Induced Heart Failure. pubmed:27555054 |
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European Journal of Pharmaceutical Sciences |
Sacubitril/valsartan (LCZ696) Significantly Reduces Aldosterone and Increases cGMP Circulating Levels in a Canine Model of RAAS Activation Doi: 10.1101/435560 |
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Nutrition |
Gut Dysbiosis Contribute to High Fructose Induced Salt Sensitive Hypertension In Sprague-Dawley Rats |
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ACTA PHARMACOLOGICA SINICA |
The vascular endothelial growth factor trap aflibercept induces vascular dysfunction and hypertension via attenuation of eNOS/NO signaling in mice 33303990 |
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Hypertens Res |
Association of Ang-(1¨C7) and des-Arg 9 BK as new biomarkers of obesity and cardiometabolic risk factors in adolescents 33568792 |
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Phosphorylation of β1-integrin in juxtaglomerular cells helps control blood pressure during the progression of diabetic nephropathy |
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Bedeutung des intrarenalen Renin-Angiotensin-Systems f¨¹r die Entwicklung der chronischen Nierenkrankheit |
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Catalog No. |
Related products for research use of Mus musculus (Mouse) Organism species |
Applications (RESEARCH USE ONLY!) |
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RPA889Mu02 |
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RPA889Mu01 |
Positive Control; Immunogen; SDS-PAGE; WB. |
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PAA889Mu02 |
WB,IHC |
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PAA889Mu01 |
WB; IHC; ICC; IP. |
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LAA889Mu71 |
WB; IHC; ICC. |
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SEA889Mu |
Enzyme-linked immunosorbent assay for Antigen Detection. |
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MEA889Mu |
Enzyme-linked immunosorbent assay for Antigen Detection. |
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LMA889Mu |
Magnetic Luminex Assay for Antigen Detection. |
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