Cloud-clone
SKU:LAA063Ga71
Biotin-Linked Polyclonal Antibody to Interleukin 17 (IL17)
Biotin-Linked Polyclonal Antibody to Interleukin 17 (IL17)
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Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.
Product No.
LAA063Ga71
Organism Species
Chicken (Gallus).
Source
Antibody labeling
Ig Type
IgG
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Label
Biotin
Original Antibody
n/a
Buffer Formulation
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Traits
Liquid
Concentration
500µg/mL
Organism Species More
n/a
Applications
WB; IHC; ICC.
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against IL17. It has been selected for its ability to recognize IL17 in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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Magazine |
Citations |
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PLOS ONE |
Impaired Autoimmune T Helper 17 Cell Responses Following DNA Vaccination against Rat Experimental Autoimmune Encephalomyelitis PubMed: PMC2577303 |
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Cellular Immunology |
Atorvastatin ameliorates experimental autoimmune neuritis by decreased Th1/Th17 cytokines and up-regulated T regulatory cells ScienceDirect: S0008874911002164 |
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The Journal of Urology |
Improvement by Phytotherapeutic Agent of Detrusor Overactivity, Down-Regulation of Pharmacological Receptors and Urinary Cytokines in Rats with Cyclophosphamide Induced Cystitis PubMed: S0022534712049087 |
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Critical Care Medicine |
Systemic release of cytokines and heat shock proteins in porcine models of polytrauma and hemorrhage PubMed: PMC3383056 |
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Lower Urinary Tract Symptoms |
Effects of Saw Palmetto Extract on Urodynamic Parameters, Bladder Muscarinic and Purinergic Receptors and Urinary Cytokines in Rats with Cyclophosphamide-Induced Cystitis Onlinelibrary: luts.12015 |
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Shock |
Expression of Hemopexin in Acute Rejection of Rat Liver Allograft Identified by Serum Proteomic Analysis. Lww: Source |
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J Vet Med Sci. |
CD4+ T Cell Cytokine Gene and Protein Expression in Duodenal Mucosa of Dogs with Inflammatory Bowel Disease Pubmed:24270804 |
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Journal of Dairy Science |
Increased blood-circulating interferon-γ, interleukin-17, and osteopontin levels in bovine paratuberculosis Pubmed:24679935 |
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Inflammation.? |
Pemetrexed Ameliorates Experimental Arthritis in Rats Pubmed:25129058 |
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Inflammation |
Lapatinib Ameliorates Experimental Arthritis in Rats Pubmed:25283886 |
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Molecular and Cellular Biochemistry |
Beta-arrestin-2 negatively modulates inflammation response in mouse chondrocytes induced by 4-mer hyaluronan oligosaccharide Pubmed:25318610 |
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Molecular Medicine Reports |
Function of interleukin?17 and ?35 in the blood of patients with hepatitis B?related liver cirrhosis Pubmed:25323532 |
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Genet Mol Res |
Protective effect and mechanism of probucol in the treatment of spinal cord injury PubMed: 26214485 |
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veterinary research forum |
Evaluation of proliferation and cytokines production by mitogen-stimulated bovine peripheral blood mononuclear cells Article_14936_6.Html: |
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Tumor Biology |
Hypoxia-induced secretion of IL-20 from adipose-derived mesenchymal stem cell promotes growth and cancer stem cell properties of Burkitt lymphoma PubMed: 26695151 |
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Clinical & Experimental Immunology |
MicroRNA‐155 may be involved in the pathogenesis of atopic dermatitis by modulating the differentiation and function of T helper type 17 (Th18) cells PubMed: 25761610 |
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J Reprod Immunol |
The immunomodulating effect of seminal plasma on T cells PubMed: 25799173 |
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Biomarkers |
Interleukin-17 levels correlate with poor prognosis and vascular endothelial growth factor concentration in the serum of patients with non-small cell lung cancer PubMed: 26301881 |
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Molecular Medicine Reports |
Tanshinone IIA attenuates experimental autoimmune encephalomyelitis in rats Pubmed:27357729 |
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SpringerPlus |
Ethyl pyruvate attenuated coxsackievirus B3-induced acute viral myocarditis by suppression ofHMGB1/RAGE/NF-ΚB pathway. Pubmed:27026909 |
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International Immunopharmacology |
Consistency and pathophysiological characterization of a rat polymicrobial sepsis model via the improved cecal ligation and puncture surgery Pubmed:26802602 |
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Journal of Agricultural Biotechnology |
Gln Attenuates LPS-induced Inflammatory Injury of Bos taurus Testis Sustentacular Cells 10610 |
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Veterinary Research Communications |
Immunological and pathological investigations in equine experimental uveitis pubmed:27344152 |
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Journal of Neuroinflammation |
Th17-skewed immune response and cluster of differentiation 40 ligand expression in canine steroid-responsive meningitis-arteritis, a large animal model for neutrophilic meningitis. pubmed:28114998 |
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American Journal of Translational Research |
Anti-inflammatory effects of Boletus edulis polysaccharide on asthma pathology pubmed:27830033 |
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Springerplus |
Ethyl pyruvate attenuated coxsackievirus B3-induced acute viral myocarditis by suppression of HMGB1/RAGE/NF-ΚB pathway pubmed:27026909 |
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Journal of Virology |
Characterization of Simian Immunodeficiency Virus Variants Anatomically Compartmentalized inPlasma and Milk in Chronically Infected African Green Monkeys. pubmed: |
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J Nephropathol |
Relationship between IL-17 serum level and ambulatory blood pressure in women with polycystic ovary syndrome pubmed:28042549 |
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Journal of Nephropathology |
Relationship between IL-17 and ambulatory blood pressure in polycystic ovary syndrome 8b168a09f5832df1b5c2f48631612458b2d8.pdf |
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Basic Clin Pharmacol Toxicol. |
Magnolol Attenuates Concanavalin A-induced Hepatic Fibrosis, Inhibits CD4+ T Helper 17 (Th17) Cell Differentiation and Suppresses Hepatic Stellate Cell Activation: Blockade of Smad3/Smad4 Signalling. pubmed:28032440 |
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Gut Pathog. |
Oral administration of Clostridium butyricum CGMCC0313‐1 reduces ovalbumin‐induced allergic airway inflammation in mice pubmed:28250847 |
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Procalcitonin und proinflammatorische Zytokine in der bronchoalveolären Lavage beim lungenkranken Pferd unter inhalativer Glukokortikoidtherapie FUDISS_thesis_000000103830 |
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Scientific Report |
Anti-asthmatic efect of pitavastatin through aerosol inhalation is associated with CD4+ CD25+ Foxp3+ T cells in an asthma mouse model pubmed:28729731 |
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Basic & Clinical Pharmacology & Toxicology |
Magnolol Attenuates Concanavalin A-induced Hepatic Fibrosis, Inhibits CD4 + T Helper 17(Th17) Cell Differentiation and Suppresses Hepatic Stellate Cell Activation: Blockade of Smad3/Smad4 Signalling doi:10.1111 |
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Academic Journal |
Antiinflammatory and antioxidant effects of gemcitabine in collagen-induced arthritis model pubmed:28618762 |
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International Journal of Clinical and Experimental Pathology |
Low-density neutrophils in severe fever with thrombocytopenia syndrome (SFTS) display decreased function to phagocytose SFTS virus and enhanced capacity to synthesize cytokines ISSN:1936-2625/IJCEP0045334 |
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Asian Pacific Society of Respirology |
Oral administration of Clostridium butyricum CGMCC0313-1 reduces ovalbumin-induced allergic airway inflammation in mice pubmed:28122397 |
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MYOPAIN |
Increased Levels of IL-17, IL-23, MIP-1α, MCP-1 and Global Leukocytes in Fibromyalgia Patients 10.1080/24708593.2017.1357664 |
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Molecular Medicine Reports |
Lower level of IL‑35 and its reduced inhibition in Th17 cells in patients with bone marrow mononuclear cells Coombs test‑positive hemocytopenia. pubmed:29257310 |
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Molecular Medicine Reports |
Interleukin-17 antagonist attenuates lung inflammation through inhibition of the ERK1/2 and NF-κB pathway in LPS-induced acute lung injury 10.3892/mmr.2017.6837 |
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ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY |
Dexamethasone reduces serum level of IL-17 in Bleomycin-A5-induced rats model of pulmonary fibrosis pubmed:28608724 |
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International Immunopharmacology |
Therapeutic effect of bone marrow mesenchymal stem cells pretreated with acetylsalicylic acid on experimental periodontitis in rats pubmed:29195233 |
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Biomedical Research |
Associations among interleukin-17, interferon-gamma, and acute coronary syndrome ISSN 0970-938X |
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Cellular Physiology and Biochemistry |
Activated Α7nachr Improves Postoperative Cognitive Dysfunction and Intestinal Injury Induced by Cardiopulmonary Bypass in Rats: Inhibition of the Proinflammatory … Pubmed:29672286 |
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Frontiers in Pharmacology |
Traditional Herbal Medicine-Derived Sulforaphene LFS-01 Reverses Colitis in Mice by Selectively Altering the Gut Microbiota and Promoting Intestinal … Pubmed:29375374 |
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Bioscience Reports |
Decreased miR-128 expression alleviated the progression of Rheumatoid arthritis by up-regulating the expression of TNFAIP3 Pubmed:29853534 |
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Medical Science Monitor |
Involvement of T-Helper 9 Activation in a Mouse Model of Allergic Rhinitis Pubmed:29982264 |
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Journal of International Medical Research |
Changes in Th1/Th2-producing cytokines during acute exacerbation chronic obstructive pulmonary disease Pubmed:29950127 |
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Canadian Journal of Physiology and Pharmacology |
Inhibition of microRNA-155 attenuates concanavalin A-induced autoimmune hepatitis by regulating Treg/Th17 cell differentiation Pubmed: 30290123 |
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BMC Microbiology |
Nystatin enhances the immune response against Candida albicans and protects the ultrastructure of the vaginal epithelium in a rat model of vulvovaginal … Pubmed: 30359236 |
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Biology of Reproduction |
Recombinant adiponectin alleviates abortion in mice by regulating Th17/Treg imbalance via p38MAPK-STAT5 pathway Pubmed: 30496353 |
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BMC MICROBIOLOGY |
Enhanced antifungal activity of bovine lactoferrin-producing probiotic Lactobacillus casei in the murine model of vulvovaginal candidiasis Pubmed: 30621597 |
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CNS Neuroscience & Therapeutics |
Negative regulation of glial Tim‐3 inhibits the secretion of inflammatory factors and modulates microglia to antiinflammatory phenotype after experimental intracerebral?… Pubmed: 30677253 |
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OPEN ACCESS MACEDONIAN JOURNAL OF MEDICAL SCIENCES |
Seluang Fish (Rasbora Spp.) Oil Decreases Inflammatory Cytokines Via Increasing Vitamin D Level in Systemic Lupus Erythematosus |
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Frontiers in Microbiology |
Local probiotic Lactobacillus crispatus and Lactobacillus delbrueckii exhibit strong antifungal effects against vulvovaginal candidiasis in a rat model |
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中国免疫学杂志 |
TRAF-6 调控TGF-β1-Smad2/Smad3 信号通路在Graves 病免疫发病机制中的作用 |
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Microbial Pathogenesis |
Therapeutic effectiveness of type I interferon in vulvovaginal candidiasis Pubmed: 31158491 |
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Inflammation |
Protein Kinase C Theta Inhibition Attenuates Lipopolysaccharide-Induced Acute Lung Injury through Notch Signaling Pathway via Suppressing Th17 Cell Response … Pubmed: 31297750 |
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international immunopharmacology |
Adenovirus-mediated down-regulation of miR-21-5p alleviates experimental autoimmune uveoretinitis in mice Pubmed: 31228813 |
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Untersuchung einer Th17-vermittelten Immunantwort bei der kaninen idiopathischen Epilepsie |
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Free Radical Biology and Medicine |
Vitamin D protects against oxidative stress, inflammation and hepatorenal damage induced by acute paracetamol toxicity in rat Pubmed: 31255668 |
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BioMed Research International |
Indoleamine 2, 3-Dioxygenase (IDO) Regulates Th17/Treg Immunity in Experimental IgA Nephropathy |
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Animals |
Anti-Inflammatory State in Arabian Horses Introduced to the Endurance Training Pubmed: 31462005 |
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World Journal of Pediatrics |
Regulation of JAK/STAT signal pathway by miR-21 in the pathogenesis of juvenile idiopathic arthritis Pubmed: 31641939 |
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Biotechnology and Applied Biochemistry |
Epigallocatechin 3‐gallate attenuates arthritis by regulating Nrf‐2, HO‐1 and cytokine levels in an experimental arthritis model Pubmed: 31746064 |
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Microbial Pathogenesis |
Tangeretin attenuates lipopolysaccharide-induced acute lung injury through Notch signaling pathway via suppressing Th17 cell response in mice Pubmed: 31676364 |
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International Journal of Rheumatic Diseases |
Effects of thalidomide on Th17, Treg cells and TGF‐β1/Smad3 pathway in a mouse model of systemic sclerosis Pubmed: 31840939 |
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Cytokine |
Levels of pro-and anti-inflammatory cytokines in cystic fibrosis patients with or without gingivitis Pubmed: 31927460 |
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international urology and nephrology |
The therapeutic effect of dendritic cells expressing indoleamine 2, 3-dioxygenase (IDO) on an IgA nephropathy mouse model Pubmed: 31894556 |
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JOURNAL OF PERIODONTAL RESEARCH |
Salivary Del‐1, IL‐17, and LFA‐1 levels in periodontal health and disease Pubmed: 32153040 |
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journal of molecular endocrinology |
LncRNA Profile in Hashimoto's Thyroiditis and Potential Function of NONHSAT079547. 2 Pubmed: 32229697 |
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Toxicol Appl Pharmacol |
Daphnetin ameliorates glucocorticoid-induced osteoporosis via activation of Wnt/GSK-3β/β-catenin signaling Pubmed: 33171191 |
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CARDIOVASCULAR DRUGS AND THERAPY |
Rhodiola crenulata reduces ventricular arrhythmia through mitigating the activation of IL-17 and inhibiting the MAPK signaling pathway Pubmed: 32946036 |
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Biomed Research International |
Effects of 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin on T Cell Differentiation in Primary Biliary Cholangitis Pubmed: 32908870 |
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J Neurosurg |
Covering the proximal nerve stump with chondroitin sulfate proteoglycans prevents traumatic painful neuroma formation by blocking axon regeneration after … Pubmed: 32470939 |
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JOURNAL OF MICROBIOLOGY |
Melatonin attenuates microbiota dysbiosis of jejunum in short-term sleep deprived mice Pubmed: 32424577 |
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bioscience reports |
Protective effect of Asarum sieboldii essential oil on ovalbumin induced allergic rhinitis in rat Pubmed: 32395767 |
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Journal of Biochemical and Molecular Toxicology |
Vitamin D3 and calcium cosupplementation alleviates cadmium hepatotoxicity in the rat: Enhanced antioxidative and anti‐inflammatory actions by remodeling cellular … |
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Revista da Associacao Medica Brasileira |
A comparison of IL-17 and IL-34 concentrations in the cerebrospinal fluid of patients with acute inflammatory demyelinating neuropathy and chronic … |
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biosciences biotechnology research asia |
Dietary Malted Barley Grain Improved Structure and Function of Spinal Cord of Mother Rats fed on a high cholesterol diet. |
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ACS Biomaterials Science & Engineering |
Tissue-Engineered Decellularized Allografts for Anterior Cruciate Ligament Reconstruction |
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Effects of minocycline on neuroinflammation, gut microbiome and hippocampal neurogenesis in rats with Gulf War Illness |
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Minocycline Alleviate A Rat Model Of Gulf War Illness Via Altering Gut Microbiome, Attenuating Neuroinflammation And Enhancing Hippocampal Neurogenesis |
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中国应用生理学杂志 |
丹参对非酒精性脂肪肝Th17细胞及相关细胞因子的影响* |
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Rev Assoc Med Bras |
A comparison of IL-17 and IL-34 concentrations in the cerebrospinal fluid of patients with acute inflammatory demyelinating neuropathy and chronic?¡ 33295414 |
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BEHAVIOURAL BRAIN RESEARCH |
Minocycline alleviates Gulf War Illness rats via altering gut microbiome, attenuating neuroinflammation and enhancing hippocampal neurogenesis 34000339 |
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Int J Clin Pract |
Serum Galectin©\3 Levels in Patients with Psoriasis 34137138 |
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cells |
The Effect of the Clenbuterol¡ª¦Â2-Adrenergic Receptor Agonist on the Peripheral Blood Mononuclear Cells Proliferation, Phenotype, Functions, and Reactive Oxygen?¡ 33920705 |
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Mediators of Inflammation |
Sparstolonin B Exerts Therapeutic Effects on Collagen-Induced Arthritis by Inhibiting the NLRP3 Inflammasome and Reducing the Activity of ¦Á1, 3 ¡ |
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CNS Neurosci Ther |
Alterations in the gut microbiome with hemorrhagic transformation in experimental stroke 34591349 |
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PLoS One |
Evaluation of the involvement of Th17-cells in the pathogenesis of canine spinal cord injury 34591917 |
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J Periodontol |
Cytokine profile in serum and gingival crevicular fluid of children with inflammatory bowel disease: A case‐control study 34730850 |
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Transl Psychiatry |
Associations between expression of indoleamine 2, 3-dioxygenase enzyme and inflammatory cytokines in patients with first-episode drug-naive … 34802039 |
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Viruses |
Interleukin-10-Mediated Lymphopenia Caused by Acute Infection with Foot-and-Mouth Disease Virus in Mice 34960627 |
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PLoS One |
Th17 cell-mediated immune response in a subpopulation of dogs with idiopathic epilepsy Pubmed:35025939 |
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Pathogens |
Elevated Levels of IL-33, IL-17 and IL-25 Indicate the Progression from Chronicity to Hepatocellular Carcinoma in Hepatitis C Virus Patients Pubmed:35056005 |
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Biomed Pharmacother |
Jiangu granule ameliorated OVX rats bone loss by modulating gut microbiota-SCFAs-Treg/Th17 axis Pubmed:35453007 |
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npj Biofilms and Microbiomes |
The microbiota-gut-kidney axis mediates host osmoregulation in a small desert mammal Pubmed:35379849 |
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Expert Opinion on Therapeutic Targets |
Dapagliflozin mitigates ovalbumin-prompted airway inflammatory-oxidative successions and associated bronchospasm in a rat model of allergic asthma Pubmed:35549595 |
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