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SKU:LAA063Ga71

Biotin-Linked Polyclonal Antibody to Interleukin 17 (IL17)

Biotin-Linked Polyclonal Antibody to Interleukin 17 (IL17)

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UOM
Concentration
Organism species

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

Product No.

LAA063Ga71

Organism Species

Chicken (Gallus).

Source

Antibody labeling

Ig Type

IgG

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Label

Biotin

Original Antibody

n/a

Buffer Formulation

PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Traits

Liquid

Concentration

500µg/mL

Organism Species More

n/a

Applications

WB; IHC; ICC.

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against IL17. It has been selected for its ability to recognize IL17 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine

Citations

PLOS ONE

Impaired Autoimmune T Helper 17 Cell Responses Following DNA Vaccination against Rat Experimental Autoimmune Encephalomyelitis PubMed: PMC2577303

Cellular Immunology

Atorvastatin ameliorates experimental autoimmune neuritis by decreased Th1/Th17 cytokines and up-regulated T regulatory cells ScienceDirect: S0008874911002164

The Journal of Urology

Improvement by Phytotherapeutic Agent of Detrusor Overactivity, Down-Regulation of Pharmacological Receptors and Urinary Cytokines in Rats with Cyclophosphamide Induced Cystitis PubMed: S0022534712049087

Critical Care Medicine

Systemic release of cytokines and heat shock proteins in porcine models of polytrauma and hemorrhage PubMed: PMC3383056

Lower Urinary Tract Symptoms

Effects of Saw Palmetto Extract on Urodynamic Parameters, Bladder Muscarinic and Purinergic Receptors and Urinary Cytokines in Rats with Cyclophosphamide-Induced Cystitis Onlinelibrary: luts.12015

Shock

Expression of Hemopexin in Acute Rejection of Rat Liver Allograft Identified by Serum Proteomic Analysis. Lww: Source

J Vet Med Sci.

CD4+ T Cell Cytokine Gene and Protein Expression in Duodenal Mucosa of Dogs with Inflammatory Bowel Disease Pubmed:24270804

Journal of Dairy Science

Increased blood-circulating interferon-γ, interleukin-17, and osteopontin levels in bovine paratuberculosis Pubmed:24679935

Inflammation.?

Pemetrexed Ameliorates Experimental Arthritis in Rats Pubmed:25129058

Inflammation

Lapatinib Ameliorates Experimental Arthritis in Rats Pubmed:25283886

Molecular and Cellular Biochemistry

Beta-arrestin-2 negatively modulates inflammation response in mouse chondrocytes induced by 4-mer hyaluronan oligosaccharide Pubmed:25318610

Molecular Medicine Reports

Function of interleukin?17 and ?35 in the blood of patients with hepatitis B?related liver cirrhosis Pubmed:25323532

Genet Mol Res

Protective effect and mechanism of probucol in the treatment of spinal cord injury PubMed: 26214485

veterinary research forum

Evaluation of proliferation and cytokines production by mitogen-stimulated bovine peripheral blood mononuclear cells Article_14936_6.Html:

Tumor Biology

Hypoxia-induced secretion of IL-20 from adipose-derived mesenchymal stem cell promotes growth and cancer stem cell properties of Burkitt lymphoma PubMed: 26695151

Clinical & Experimental Immunology

MicroRNA‐155 may be involved in the pathogenesis of atopic dermatitis by modulating the differentiation and function of T helper type 17 (Th18) cells PubMed: 25761610

J Reprod Immunol

The immunomodulating effect of seminal plasma on T cells PubMed: 25799173

Biomarkers

Interleukin-17 levels correlate with poor prognosis and vascular endothelial growth factor concentration in the serum of patients with non-small cell lung cancer PubMed: 26301881

Molecular Medicine Reports

Tanshinone IIA attenuates experimental autoimmune encephalomyelitis in rats Pubmed:27357729

SpringerPlus

Ethyl pyruvate attenuated coxsackievirus B3-induced acute viral myocarditis by suppression ofHMGB1/RAGE/NF-ΚB pathway. Pubmed:27026909

International Immunopharmacology

Consistency and pathophysiological characterization of a rat polymicrobial sepsis model via the improved cecal ligation and puncture surgery Pubmed:26802602

Journal of Agricultural Biotechnology

Gln Attenuates LPS-induced Inflammatory Injury of Bos taurus Testis Sustentacular Cells 10610

Veterinary Research Communications

Immunological and pathological investigations in equine experimental uveitis pubmed:27344152

Journal of Neuroinflammation

Th17-skewed immune response and cluster of differentiation 40 ligand expression in canine steroid-responsive meningitis-arteritis, a large animal model for neutrophilic meningitis. pubmed:28114998

American Journal of Translational Research

Anti-inflammatory effects of Boletus edulis polysaccharide on asthma pathology pubmed:27830033

Springerplus

Ethyl pyruvate attenuated coxsackievirus B3-induced acute viral myocarditis by suppression of HMGB1/RAGE/NF-ΚB pathway pubmed:27026909

Journal of Virology

Characterization of Simian Immunodeficiency Virus Variants Anatomically Compartmentalized inPlasma and Milk in Chronically Infected African Green Monkeys. pubmed:

J Nephropathol

Relationship between IL-17 serum level and ambulatory blood pressure in women with polycystic ovary syndrome pubmed:28042549

Journal of Nephropathology

Relationship between IL-17 and ambulatory blood pressure in polycystic ovary syndrome 8b168a09f5832df1b5c2f48631612458b2d8.pdf

Basic Clin Pharmacol Toxicol.

Magnolol Attenuates Concanavalin A-induced Hepatic Fibrosis, Inhibits CD4+ T Helper 17 (Th17) Cell Differentiation and Suppresses Hepatic Stellate Cell Activation: Blockade of Smad3/Smad4 Signalling. pubmed:28032440

Gut Pathog.

Oral administration of Clostridium butyricum CGMCC0313‐1 reduces ovalbumin‐induced allergic airway inflammation in mice pubmed:28250847


Procalcitonin und proinflammatorische Zytokine in der bronchoalveolären Lavage beim lungenkranken Pferd unter inhalativer Glukokortikoidtherapie FUDISS_thesis_000000103830

Scientific Report

Anti-asthmatic efect of pitavastatin through aerosol inhalation is associated with CD4+ CD25+ Foxp3+ T cells in an asthma mouse model pubmed:28729731

Basic & Clinical Pharmacology & Toxicology

Magnolol Attenuates Concanavalin A-induced Hepatic Fibrosis, Inhibits CD4 + T Helper 17(Th17) Cell Differentiation and Suppresses Hepatic Stellate Cell Activation: Blockade of Smad3/Smad4 Signalling doi:10.1111

Academic Journal

Antiinflammatory and antioxidant effects of gemcitabine in collagen-induced arthritis model pubmed:28618762

International Journal of Clinical and Experimental Pathology

Low-density neutrophils in severe fever with thrombocytopenia syndrome (SFTS) display decreased function to phagocytose SFTS virus and enhanced capacity to synthesize cytokines ISSN:1936-2625/IJCEP0045334

Asian Pacific Society of Respirology

Oral administration of Clostridium butyricum CGMCC0313-1 reduces ovalbumin-induced allergic airway inflammation in mice pubmed:28122397

MYOPAIN

Increased Levels of IL-17, IL-23, MIP-1α, MCP-1 and Global Leukocytes in Fibromyalgia Patients 10.1080/24708593.2017.1357664

Molecular Medicine Reports

Lower level of IL‑35 and its reduced inhibition in Th17 cells in patients with bone marrow mononuclear cells Coombs test‑positive hemocytopenia. pubmed:29257310

Molecular Medicine Reports

Interleukin-17 antagonist attenuates lung inflammation through inhibition of the ERK1/2 and NF-κB pathway in LPS-induced acute lung injury 10.3892/mmr.2017.6837

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY 

Dexamethasone reduces serum level of IL-17 in Bleomycin-A5-induced rats model of pulmonary fibrosis pubmed:28608724

International Immunopharmacology

Therapeutic effect of bone marrow mesenchymal stem cells pretreated with acetylsalicylic acid on experimental periodontitis in rats pubmed:29195233

Biomedical Research

Associations among interleukin-17, interferon-gamma, and acute coronary syndrome ISSN 0970-938X

Cellular Physiology and Biochemistry

Activated Α7nachr Improves Postoperative Cognitive Dysfunction and Intestinal Injury Induced by Cardiopulmonary Bypass in Rats: Inhibition of the Proinflammatory … Pubmed:29672286

Frontiers in Pharmacology

Traditional Herbal Medicine-Derived Sulforaphene LFS-01 Reverses Colitis in Mice by Selectively Altering the Gut Microbiota and Promoting Intestinal … Pubmed:29375374

Bioscience Reports

Decreased miR-128 expression alleviated the progression of Rheumatoid arthritis by up-regulating the expression of TNFAIP3 Pubmed:29853534

Medical Science Monitor

Involvement of T-Helper 9 Activation in a Mouse Model of Allergic Rhinitis Pubmed:29982264

Journal of International Medical Research

Changes in Th1/Th2-producing cytokines during acute exacerbation chronic obstructive pulmonary disease Pubmed:29950127

Canadian Journal of Physiology and Pharmacology

Inhibition of microRNA-155 attenuates concanavalin A-induced autoimmune hepatitis by regulating Treg/Th17 cell differentiation Pubmed: 30290123

BMC Microbiology

Nystatin enhances the immune response against Candida albicans and protects the ultrastructure of the vaginal epithelium in a rat model of vulvovaginal … Pubmed: 30359236

Biology of Reproduction

Recombinant adiponectin alleviates abortion in mice by regulating Th17/Treg imbalance via p38MAPK-STAT5 pathway Pubmed: 30496353

BMC MICROBIOLOGY

Enhanced antifungal activity of bovine lactoferrin-producing probiotic Lactobacillus casei in the murine model of vulvovaginal candidiasis Pubmed: 30621597

CNS Neuroscience & Therapeutics

Negative regulation of glial Tim‐3 inhibits the secretion of inflammatory factors and modulates microglia to antiinflammatory phenotype after experimental intracerebral?… Pubmed: 30677253

OPEN ACCESS MACEDONIAN JOURNAL OF MEDICAL SCIENCES

Seluang Fish (Rasbora Spp.) Oil Decreases Inflammatory Cytokines Via Increasing Vitamin D Level in Systemic Lupus Erythematosus

Frontiers in Microbiology

Local probiotic Lactobacillus crispatus and Lactobacillus delbrueckii exhibit strong antifungal effects against vulvovaginal candidiasis in a rat model

中国免疫学杂志

TRAF-6 调控TGF-β1-Smad2/Smad3 信号通路在Graves 病免疫发病机制中的作用

Microbial Pathogenesis

Therapeutic effectiveness of type I interferon in vulvovaginal candidiasis Pubmed: 31158491

Inflammation

Protein Kinase C Theta Inhibition Attenuates Lipopolysaccharide-Induced Acute Lung Injury through Notch Signaling Pathway via Suppressing Th17 Cell Response … Pubmed: 31297750

international immunopharmacology

Adenovirus-mediated down-regulation of miR-21-5p alleviates experimental autoimmune uveoretinitis in mice Pubmed: 31228813


Untersuchung einer Th17-vermittelten Immunantwort bei der kaninen idiopathischen Epilepsie

Free Radical Biology and Medicine

Vitamin D protects against oxidative stress, inflammation and hepatorenal damage induced by acute paracetamol toxicity in rat Pubmed: 31255668

BioMed Research International

Indoleamine 2, 3-Dioxygenase (IDO) Regulates Th17/Treg Immunity in Experimental IgA Nephropathy

Animals

Anti-Inflammatory State in Arabian Horses Introduced to the Endurance Training Pubmed: 31462005

World Journal of Pediatrics

Regulation of JAK/STAT signal pathway by miR-21 in the pathogenesis of juvenile idiopathic arthritis Pubmed: 31641939

Biotechnology and Applied Biochemistry

Epigallocatechin 3‐gallate attenuates arthritis by regulating Nrf‐2, HO‐1 and cytokine levels in an experimental arthritis model Pubmed: 31746064

Microbial Pathogenesis

Tangeretin attenuates lipopolysaccharide-induced acute lung injury through Notch signaling pathway via suppressing Th17 cell response in mice Pubmed: 31676364

International Journal of Rheumatic Diseases

Effects of thalidomide on Th17, Treg cells and TGF‐β1/Smad3 pathway in a mouse model of systemic sclerosis Pubmed: 31840939

Cytokine

Levels of pro-and anti-inflammatory cytokines in cystic fibrosis patients with or without gingivitis Pubmed: 31927460

international urology and nephrology

The therapeutic effect of dendritic cells expressing indoleamine 2, 3-dioxygenase (IDO) on an IgA nephropathy mouse model Pubmed: 31894556

JOURNAL OF PERIODONTAL RESEARCH

Salivary Del‐1, IL‐17, and LFA‐1 levels in periodontal health and disease Pubmed: 32153040

journal of molecular endocrinology

LncRNA Profile in Hashimoto's Thyroiditis and Potential Function of NONHSAT079547. 2 Pubmed: 32229697

Toxicol Appl Pharmacol

Daphnetin ameliorates glucocorticoid-induced osteoporosis via activation of Wnt/GSK-3β/β-catenin signaling Pubmed: 33171191

CARDIOVASCULAR DRUGS AND THERAPY

Rhodiola crenulata reduces ventricular arrhythmia through mitigating the activation of IL-17 and inhibiting the MAPK signaling pathway Pubmed: 32946036

Biomed Research International

Effects of 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin on T Cell Differentiation in Primary Biliary Cholangitis Pubmed: 32908870

J Neurosurg

Covering the proximal nerve stump with chondroitin sulfate proteoglycans prevents traumatic painful neuroma formation by blocking axon regeneration after … Pubmed: 32470939

JOURNAL OF MICROBIOLOGY

Melatonin attenuates microbiota dysbiosis of jejunum in short-term sleep deprived mice Pubmed: 32424577

bioscience reports

Protective effect of Asarum sieboldii essential oil on ovalbumin induced allergic rhinitis in rat Pubmed: 32395767

Journal of Biochemical and Molecular Toxicology

Vitamin D3 and calcium cosupplementation alleviates cadmium hepatotoxicity in the rat: Enhanced antioxidative and anti‐inflammatory actions by remodeling cellular …

Revista da Associacao Medica Brasileira

A comparison of IL-17 and IL-34 concentrations in the cerebrospinal fluid of patients with acute inflammatory demyelinating neuropathy and chronic …

biosciences biotechnology research asia

Dietary Malted Barley Grain Improved Structure and Function of Spinal Cord of Mother Rats fed on a high cholesterol diet.

ACS Biomaterials Science & Engineering

Tissue-Engineered Decellularized Allografts for Anterior Cruciate Ligament Reconstruction


Effects of minocycline on neuroinflammation, gut microbiome and hippocampal neurogenesis in rats with Gulf War Illness


Minocycline Alleviate A Rat Model Of Gulf War Illness Via Altering Gut Microbiome, Attenuating Neuroinflammation And Enhancing Hippocampal Neurogenesis

中国应用生理学杂志

丹参对非酒精性脂肪肝Th17细胞及相关细胞因子的影响*

Rev Assoc Med Bras

A comparison of IL-17 and IL-34 concentrations in the cerebrospinal fluid of patients with acute inflammatory demyelinating neuropathy and chronic?¡­ 33295414

BEHAVIOURAL BRAIN RESEARCH

Minocycline alleviates Gulf War Illness rats via altering gut microbiome, attenuating neuroinflammation and enhancing hippocampal neurogenesis 34000339

Int J Clin Pract

Serum Galectin©\3 Levels in Patients with Psoriasis 34137138

cells

The Effect of the Clenbuterol¡ª¦Â2-Adrenergic Receptor Agonist on the Peripheral Blood Mononuclear Cells Proliferation, Phenotype, Functions, and Reactive Oxygen?¡­ 33920705

Mediators of Inflammation

Sparstolonin B Exerts Therapeutic Effects on Collagen-Induced Arthritis by Inhibiting the NLRP3 Inflammasome and Reducing the Activity of ¦Á1, 3 ¡­

CNS Neurosci Ther

Alterations in the gut microbiome with hemorrhagic transformation in experimental stroke 34591349

PLoS One

Evaluation of the involvement of Th17-cells in the pathogenesis of canine spinal cord injury 34591917

J Periodontol

Cytokine profile in serum and gingival crevicular fluid of children with inflammatory bowel disease: A case‐control study 34730850

Transl Psychiatry

Associations between expression of indoleamine 2, 3-dioxygenase enzyme and inflammatory cytokines in patients with first-episode drug-naive … 34802039

Viruses

Interleukin-10-Mediated Lymphopenia Caused by Acute Infection with Foot-and-Mouth Disease Virus in Mice 34960627

PLoS One

Th17 cell-mediated immune response in a subpopulation of dogs with idiopathic epilepsy Pubmed:35025939

Pathogens

Elevated Levels of IL-33, IL-17 and IL-25 Indicate the Progression from Chronicity to Hepatocellular Carcinoma in Hepatitis C Virus Patients Pubmed:35056005

Biomed Pharmacother

Jiangu granule ameliorated OVX rats bone loss by modulating gut microbiota-SCFAs-Treg/Th17 axis Pubmed:35453007

npj Biofilms and Microbiomes

The microbiota-gut-kidney axis mediates host osmoregulation in a small desert mammal Pubmed:35379849

Expert Opinion on Therapeutic Targets

Dapagliflozin mitigates ovalbumin-prompted airway inflammatory-oxidative successions and associated bronchospasm in a rat model of allergic asthma Pubmed:35549595


Catalog No.

Related products for research use of Chicken (Gallus) Organism species

Applications (RESEARCH USE ONLY!)

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WB; IHC; ICC.

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Magnetic Luminex Assay for Antigen Detection.

 

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