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SKU:LAB809Hu71

Biotin-Linked Polyclonal Antibody to Selenoprotein P1, Plasma (SEPP1)

Biotin-Linked Polyclonal Antibody to Selenoprotein P1, Plasma (SEPP1)

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UOM
Concentration
Organism species

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

Product No.

LAB809Hu71

Organism Species

Homo sapiens (Human) Same name, Different species.

Source

Antibody labeling

Ig Type

IgG

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Label

Biotin

Original Antibody

n/a

Buffer Formulation

PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Traits

Liquid

Concentration

500µg/mL

Organism Species More

n/a

Applications

WB; IHC; ICC.

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against SEPP1. It has been selected for its ability to recognize SEPP1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine

Citations

The Journal of Clinical Endocrinology & Metabolism

Serum Selenoprotein P Levels in Patients with Type 2 Diabetes and Prediabetes: Implications for Insulin Resistance, Inflammation, and Atherosclerosis PubMed: 21677040

Diabetes & metabolism journal

Increased Selenoprotein P Levels in Subjects with Visceral Obesity and Nonalcoholic Fatty Liver Disease PubMed: 23439771

Journal of Pediatric Biochemistry

Trace elements, heavy metals and vitamins in Egyptian school children with iron deficiency anemia Metapress:Source

Journal of Trace Elements in Medicine and Biology

Selenium and its relationship with selenoprotein P and glutathione peroxidase in children and adolescents with Hashimoto's thyroiditis and hypothyroidism PubMed: 26854239

OBES RES CLIN PRACT/OBESITY RESEARCH & CLINICAL PRACTICE

Selenoprotein P is elevated in individuals with obesity, but is not independently associated withinsulin resistance. pubmed:27524654

Annals of Nutrition and Metabolism

Acute Overfeeding Does Not Alter Liver or Adipose Tissue-Derived Cytokines in HealthyHumans. pubmed:27832637

European Journal of Nutrition

DNA damage and oxidative stress response to selenium yeast in the non-smoking individuals: ashort-term supplementation trial with respect to GPX1 and SEPP1 polymorphism. pubmed:26658762

South. Clin. Ist. Euras.

Evaluation of the Relationship Between Insulin Resistance and Selenoprotein P in Patients with Polycystic Ovary Syndrome DOI: 10.14744/scie.2017.87597

Arch Endocrinol Metab

Serum selenium and selenoprotein-P levels in autoimmune thyroid dieases patients in a select center a transversal study DOI: 10.1590/2359-3997000000309

British Journal of Nutrition

Selenium, selenoproteins and selenometabolites in mothers and babies at the time of birth pubmed:28534447

Journal of Trace Elements in Medicine and Biology

Biomarkers of selenium status and antioxidant effect in workers occupationally exposed to mercury Pubmed:29895371

Biological & Pharmceutical Bulletin

Comparison of Human Selenoprotein P Determinants in Serum between Our Original Methods and Commercially Available Kits Pubmed:29709922

Diabetologia

Non-alcoholic fatty liver disease in the first trimester and subsequent development of gestational diabetes mellitus Pubmed: 30470912

Biological Trace Element Research

Selenium Levels in Community Dwellers with Type 2 Diabetes Mellitus Pubmed: 30725267

Advances in Medical Sciences

Can hepatokines be regarded as novel non-invasive serum biomarkers of intrahepatic lipid content in obese children? Pubmed: 30921653


Acute swimming exercise, but not exposure to moderate hypoxic conditions reduces circulating selenoprotein P levels in short-term, high-fat diet-fed rats Pubmed: 31236416

Hormones

Selenium and selenoprotein P in nonalcoholic fatty liver disease Pubmed: 31493247

Bull Environ Contam Toxicol

Soil Selenium Concentration and Residents Daily Dietary Intake in a Selenosis Area: A Preliminary Study in Yutangba Village, Enshi City, China Pubmed: 32909074

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Higher Serum Selenoprotein P Level as a Novel Inductor of Metabolic Complications in Psoriasis Pubmed: 32605214


Circulating hepassocin level in patients with stable angina is associated with fatty liver and renal function

Nat Immunol

Selenium–GPX4 axis protects follicular helper T cells from ferroptosis 34413521

Reviews in Cardiovascular Medicine

Selenoprotein P-1 (SEPP1) as An Early Biomarker of Acute Kidney Injury in Patients Undergoing Cardiopulmonary Bypass


Catalog No.

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Applications (RESEARCH USE ONLY!)

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Biotin-Linked Polyclonal Antibody to Selenoprotein P1, Plasma (SEPP1)

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Monoclonal Antibody to Selenoprotein P1, Plasma (SEPP1)

WB; IHC; ICC; IP.

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WB; IHC; ICC; IP.

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Monoclonal Antibody to Selenoprotein P1, Plasma (SEPP1)

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ELISA Kit for Selenoprotein P1, Plasma (SEPP1)

Enzyme-linked immunosorbent assay for Antigen Detection.

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Magnetic Luminex Assay Kit for Selenoprotein P1, Plasma (SEPP1) ,etc.

Magnetic Luminex Assay for Antigen Detection.

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