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SKU:LAA372Hu71

Biotin-Linked Polyclonal Antibody to Gelsolin (GSN)

Biotin-Linked Polyclonal Antibody to Gelsolin (GSN)

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UOM
Concentration
Organism species

Western blotting: 0.5-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.

Product No.

LAA372Hu71

Organism Species

Homo sapiens (Human).

Source

Antibody labeling

Ig Type

IgG

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Label

Biotin

Original Antibody

PAA372Hu01-Polyclonal Antibody to Gelsolin (GSN)

Buffer Formulation

0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Traits

Liquid

Concentration

500µg/mL

Organism Species More

n/a

Applications

WB; IHC; ICC.

If the antibody is used in flow cytometry, please check FCM antibodies

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against GSN. It has been selected for its ability to recognize GSN in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine

Citations

Neurochmical Research

Gelsolin in Cerebrospinal Fluid as a Potential Biomarker of Epilepsy SpringerLink: 3585r8h46q7r0171

Journal of Neuroinflammation

Treatment with gelsolin reduces brain inflammation and apoptotic signaling in mice following thermal injury BioMed: 17422094

Biomedical Engineering and Informatics

Application of iTRAQ quantitative proteomics in identification of serum biomarkers in breast cancer IEEE: 6098563

European Journal of Obstetrics & Gynecology and Reproductive Biology

Investigation of the actin scavenging system in pre-eclampsia Pubmed: 24239294

The Annals of Thoracic Surgery

Proteomic Study Reveals Plasma Protein Changes in Congenital Heart Diseases Pubmed: 24565402

BMC Anesthesiol.?

The role of plasma gelsolin in cardiopulmonary bypass induced acute lung injury in infants and young children: a pilot study Pubmed:Pmc4132929

Cell Biochemistry and Biophysics

Gelsolin: Role of a Functional Protein in Mitigating Radiation Injury Pubmed:25164111

Neurosci Lett

Plasma gelsolin and matrix metalloproteinase 3 as potential biomarkers for Alzheimer disease PubMed: 25864780

Proteomics Clinical Applications

Comparative mass spectrometric and immunoassay‐based proteome analysis in serum of Duchenne muscular dystrophy patients Pubmed:26680509

PROTEOMICS - Clinical Applications

Comparative mass spectrometric and immunoassay-based proteome analysis in serum ofDuchenne muscular dystrophy patients. pubmed:26680509

Medicina Intensiva

Serum gelsolin levels in aneurismal subarachnoid hemorrhage: Preliminary results. pubmed:28365030

Journal of Alzheimers Disease

Urine-Based Biomarkers for Alzheimer's Disease Identified Through Coupling Computational and Experimental Methods Pubmed:30040720

World Journal of Pediatrics

Plasma gelsolin level predicts acute kidney injury after cardiopulmonary bypass in infants and young children Pubmed:29427164

Biomedicines

Production and Secretion of Gelsolin by Both Human Macrophage-and Fibroblast-like Synoviocytes and GSN Modulation in the Synovial Fluid of Patients with Various … Pubmed:35327525


Catalog No.

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