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SKU:PAK552Ge01

Polyclonal Antibody to Quinolinic Acid (QA)

Polyclonal Antibody to Quinolinic Acid (QA)

Regular price $398.00 USD
Regular price Sale price $398.00 USD
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UOM
Concentration
Organism species

Immunohistochemistry: 5-20µg/mL;
;Immunocytochemistry: 5-20µg/mL;
;Optimal working dilutions must be determined by end user.

Product No.

PAK552Ge01

Organism Species

Pan-species (General).

Source

Polyclonal antibody preparation

Host

Rabbit

Potency

n/a

Ig Type

IgG

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Label

None

Immunogen

CPK552Ge21-OVA Conjugated Quinolinic Acid (QA)

Buffer Formulation

0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Traits

Liquid

Concentration

0.5mg/ml

Organism Species More

n/a

Applications

ELISA, CLIA. / IHC-Fr, ICC, IP (predicted).

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against QA. It has been selected for its ability to recognize QA in ELISA and CLIA.

USAGE

Enzyme-Linked Immune Sorbent Assay:384µg/ml
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine Citations
plos one M30 Antagonizes Indoleamine 2,3-Dioxygenase Activation and Neurodegeneration Induced by Corticosterone in the Hippocampus. pubmed:27870896
Plos One Monoamine oxidase A upregulated by chronic intermittent hypoxia activates indoleamine 2, 3-dioxygenase and neurodegeneration pubmed:28599322
Molecular Neurobiology Chronic Mild Stress Alters Kynurenine Pathways Changing the Glutamate Neurotransmission in Frontal Cortex of Rats Pubmed:29725904
american journal of physiology-cell physiology Exercise training impacts skeletal muscle gene expression related to the kynurenine pathway Pubmed: 30649918
journal of neuroscience research Modification of kynurenine pathway via inhibition of kynurenine hydroxylase attenuates surgical brain injury complications in a male rat model Pubmed: 31257634
Scientific Reports Serotonin is the main tryptophan metabolite associated with psychiatric comorbidity in abstinent cocaine-addicted patients Pubmed: 31727978
EBioMedicine Kynurenine 3-monooxygenase upregulates pluripotent genes through β-catenin and promotes triple-negative breast cancer progression Pubmed: 32268268
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