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SKU:MAJ557Hu21
Monoclonal Antibody to Beclin 1 (BECN1)
Monoclonal Antibody to Beclin 1 (BECN1)
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Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.
Product No.
MAJ557Hu21
Organism Species
Homo sapiens (Human).
Source
Monoclonal antibody preparation
Host
Mouse
Potency (Clone Number)
C12
Ig Isotype
IgG1 Kappa
Purification
Protein A + Protein G affinity chromatography
Label
None
Immunogen
RPJ557Hu01-Recombinant Beclin 1 (BECN1)
Buffer Formulation
0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Traits
Liquid
Concentration
1mg/ml
Organism Species More
Rattus norvegicus (Rat), Canis familiaris; Canine (Dog)
Applications
WB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a mouse monoclonal antibody raised against BECN1. It has been selected for its ability to recognize BECN1 in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.01-5µg/mL;
Immunohistochemistry: 5-30µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Rejuvenation Res. | Can Enhanced Autophagy be Associated with Human Longevity? Serum Levels of the Autophagy Biomarker Beclin-1 are Increased in Healthy Centenarians Pubmed:25307612 |
| J Cosmet Dermatol | A peel-off facial mask comprising myoinositol and trehalose-loaded liposomes improves adult female acne by reducing local hyperandrogenism and activating autophagy pubmed:28342238 |
| Tumor Biology | The novel CXCR4 antagonist, PRX177561, reduces tumor cell proliferation and accelerates cancer stem cell differentiation in glioblastoma preclinical models pubmed:28639900 |
| 19 | Beclin1 circulating levels and accelerated ageing markers in COPD DOI: 10.1183/1393003.congress-2017.PA1018 |
| Cell Death & Disease | Beclin1 circulating levels and accelerated aging markers in COPD Pubmed:29402890 |
| Clinica Chimica Acta | A novel combined score of biomarkers in sputum may be an indicator for lung cancer: A pilot study Doi: 10.1016/j.cca.2018.09.027 |
| International Journal of Clinical and Experimental Pathology | Serum concentration of autophagy-related protein 7 is correlated with non-alcoholic fatty liver disease in Chinese adults |
| EXPERIMENTAL AND THERAPEUTIC MEDICINE | Crosstalk between vitamin D axis, inflammation and host immunity mechanisms: A prospective study 33936265 |
| International Journal for Research in Applied Sciences and Biotechnology | Inhibition of HepG-2 Cells (Liver Cancer Cell Line) Viability by 3-Hydroxypyridine-2-Carboxaldehyde N (4)-Methylthiosemicarbazone |
| BIOMARKERS OF AUTOPHAGY AND ANTIVIRAL ROLE OF PLACENTA FOR PREDICTING PRETERM DELIVERY IN PATIENTS WITH PRETERM DELIVERY?¡ | |
| European Journal of Natural History | IDENTIFICATION OF FACTORS CONNECTED WITH AUTOPHAGY ACTIVITY UNDER CONDITIONS OF PARTIAL NUTRITIONAL DEPRIVATION IN MEN |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| RPJ557Hu01 | Recombinant Beclin 1 (BECN1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAJ557Hu01 | Polyclonal Antibody to Beclin 1 (BECN1) | WB,IHC |
| MAJ557Hu21 | Monoclonal Antibody to Beclin 1 (BECN1) | WB; IHC; ICC; IP. |
| MAJ557Hu22 | Monoclonal Antibody to Beclin 1 (BECN1) | WB; IHC; ICC; IP. |
| MAJ557Hu23 | Monoclonal Antibody to Beclin 1 (BECN1) | WB; IHC; ICC; IP. |
| MAJ557Hu24 | Monoclonal Antibody to Beclin 1 (BECN1) | WB; IHC; ICC; IP. |
| MAJ557Hu25 | Monoclonal Antibody to Beclin 1 (BECN1) | WB; IHC; ICC; IP. |
| SEJ557Hu | ELISA Kit for Beclin 1 (BECN1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMJ557Hu | Magnetic Luminex Assay Kit for Beclin 1 (BECN1) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
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