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SKU:PAF422Hu02
Polyclonal Antibody to Fibulin 3 (FBLN3)
Polyclonal Antibody to Fibulin 3 (FBLN3)
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Western blotting: 0.5-2µg/mL;
;Immunohistochemistry: 5-20µg/mL;
;Immunocytochemistry: 5-20µg/mL;
;Optimal working dilutions must be determined by end user.
Product No.
PAF422Hu02
Organism Species
Homo sapiens (Human).
Source
Polyclonal antibody preparation
Host
Rabbit
Potency
n/a
Ig Type
IgG
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Label
None
Immunogen
RPF422Hu02-Recombinant Fibulin 3 (FBLN3)
Buffer Formulation
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Traits
Liquid
Concentration
500µg/mL
Organism Species More
Mus musculus (Mouse), Rattus norvegicus (Rat)
Applications
WB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against FBLN3. It has been selected for its ability to recognize FBLN3 in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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Magazine |
Citations |
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1 |
Fibulin-3 as a Blood and Effusion Biomarker for Pleural Mesothelioma PubMed: PMC3761217 |
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Anticancer Res. |
YKL-40 and mesothelin in the blood of patients with malignant mesothelioma, lung cancer and asbestosis. Pubmed: 24324091 |
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Oncology Reports |
Role of fibulin-3 in lung cancer: In vivo and in vitro analyses Spandidos-publications: Source |
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Current Pulmonology Reports |
Discovery of new biomarkers for malignant mesothelioma Springer:Source |
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United States Patent Application 20140378336 |
DIAGNOSIS OF CELL PROLIFERATIVE DISEASES Freepatentsonline:Source |
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Thorax. |
Comparison of fibulin-3 and mesothelin as markers in malignant mesothelioma Pubmed:Pmc4174124 |
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Egyptian Journal of Chest Diseases and Tuberculosis |
Value of plasma and pleural effusion fibulin-3 levels in the diagnosis of malignant pleural mesothelioma effusions Pubmed:23050525 |
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Radiol Oncol |
Fibulin-3 as a biomarker of response to treatment in malignant mesothelioma PubMed: 26401134 |
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British Journal of Cancer |
Fibulin-3 levels in malignant pleural mesothelioma are associated with prognosis but not diagnosis PubMed: 26263483 |
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J Thorac Oncol. |
Plasma Biomarker Enrichment of Clinical Prognostic Indices in Malignant Pleural Mesothelioma. Pubmed:26903362 |
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BMJ Open |
Diagnostic and Prognostic Biomarkers in the Rational Assessment of Mesothelioma (DIAPHRAGM) study: protocol of a prospective, multicentre, observational study pubmed:27884852 |
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25 |
HMGB1 and its hyperacetylated isoform are sensitive and specific serum biomarkers to detect asbestos exposure and to identify mesothelioma patients pubmed:26733616 |
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BMJ Journals |
Diagnostic and Prognostic Biomarkers in the Rational Assessment of Mesothelioma (DIAPHRAGM) study: protocol of a prospective, multicentre, observational … e013324.abstract |
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Anticancer Res. |
Comparison of the Diagnostic Performance of Fibulin-3 and Mesothelin in Patients with Pleural Effusions from Malignant Mesothelioma. pubmed:28314308 |
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Dis Markers. |
A Novel Panel of Serum Biomarkers for MPM Diagnosis. pubmed:28348450 |
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The Knee |
Association of fibulin-3 concentrations with the presence and severity of knee osteoarthritis: A cross-sectional study pubmed:29195846 |
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Disease markers |
Plasma Fibulin-3 as a Potential Biomarker for Patients with Asbestos-Related Diseases in the Han Population pubmed:29200597 |
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Molecular Medicine Reports |
Placental protein 14 as a potential biomarker for diagnosis of preterm premature rupture of membranes Pubmed:29749501 |
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Oncotarget |
The matrix protein Fibulin-3 promotes KISS1R induced triple negative breast cancer cell invasion Pubmed:30046386 |
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Advances in Clinical and Experimental Medicine |
Fibulin-3 and other cartilage metabolism biomarkers in relationship to calprotectin (MRP8/14) and disease activity in rheumatoid arthritis patients treated with … 68362.pdf |
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PLoS One |
Prediction of pneumoconiosis by serum and urinary biomarkers in workers exposed to asbestos-contaminated minerals Pubmed: 30946771 |
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Catalog No. |
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