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SKU:PAA485Ra08

Polyclonal Antibody to N-Terminal Pro-Brain Natriuretic Peptide (NT-ProBNP)

Polyclonal Antibody to N-Terminal Pro-Brain Natriuretic Peptide (NT-ProBNP)

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UOM
Concentration
Organism species

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

Product No.

PAA485Ra08

Organism Species

Rattus norvegicus (Rat).

Source

Polyclonal antibody preparation

Host

Rabbit

Potency

n/a

Ig Type

IgG

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Label

None

Immunogen

CPA485Ra21-OVA Conjugated N-Terminal Pro-Brain Natriuretic Peptide (NT-ProBNP)

Buffer Formulation

0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Traits

Liquid

Concentration

1mg/ml

Organism Species More

n/a

Applications

WB; IHC; ICC; IP.

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against NT-ProBNP. It has been selected for its ability to recognize NT-ProBNP in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine

Citations

Eur Rev Med Pharmacol Sci.

The role of serum n-terminal pro-brain natriuretic peptide in transient tachypnea of the newborn Europeanreview: Source

Transplantation Proceedings

Vascular Adhesion Protein-1, a Novel Molecule, in Kidney and Heart Allograft Recipients Pubmed: 23769096

34

Paradoxical low-flow, low-gradient aortic stenosis despite preserved left ventricular ejection fraction: new insights from weights of operatively excised aortic valves Pubmed: 24755006

Integrative Medicine Insights

A Randomized Controlled Trial to Study the Effect of Yoga Therapy on Cardiac Function and N Terminal Pro BNP in Heart Failure NCBI: PMC3981569

Liver Int.?

Diabetes enhances the intrahepatic vascular response to endothelin-1 in cirrhotic rats: association with the ETA receptor and pERK up-regulation. Pubmed:24636620

Eur J Heart Fail.

Growth-differentiation factor 15 and osteoprotegerin in acute myocardial infarction complicated by cardiogenic shock: a biomarker substudy of the IABP-SHOCK II-trial. Pubmed:24903195

Scientific Reports

Biomarkers and Echocardiographic Predictors of Myocardial Dysfunction in Patients with Hypertension PubMed: 25747153

Int J Mol Sci

The Multi-Biomarker Approach for Heart Failure in Patients with Hypertension PubMed: 25984599

scientific reports

Effect of Treatment on Body Fluid in Patients with Unilateral Aldosterone Producing Adenoma: Adrenalectomy versus Spironolactone PubMed: 26477337

Liver Int

Diabetes enhances the intrahepatic vascular response to endothelin‐1 in cirrhotic rats: association with the ETA receptor and pERK up‐regulation PubMed: 24636620

Int J Clin Exp Pathol

Qiliqiangxin improves cardiac function and attenuates cardiac remodeling in rats with experimental myocardial infarction PubMed: 26261541

Iranian Journal of Pediatrics

NT-proBNP in Children With Left to Right Shunt and Dilated Cardiomyopathy serve:4485

International Journal of Cardiology

Human myoblast transplantation in mice infarcted heart alters the expression profile of cardiac genes associated with left ventricle remodeling Pubmed:26457413

IJC Heart & Vasculature

Cardiovascular changes in patients with non-severe Plasmodium vivax malaria article:S2352-9067(16)30010-0

Heart Lung Circ

Soluble Glycoprotein 130 and Heat Shock Protein 27 as Novel Candidate Biomarkers of Chronic Heart Failure with Preserved Ejection Fraction Pubmed:27067668

International journal of cardiology

Differences in biochemical and genetic biomarkers in patients with heart failure of various etiologies. pubmed:27448535

Experimental and Therapeutic Medicine

Expression of pericardial fluid T-cells and related inflammatory cytokines in patients with chronic heart failure. pubmed:28565777

Journal of Cardiovascular Electrophysiology

Effect of Cardiac Resynchronization Therapy on Myocardial Fibrosis and Relevant Cytokines in a Canine Model With Experimental Heart Failure. pubmed:28127817

Journal of Cardiovascular Ecography

Study of Vitamin D Status in Patients with Dilated Cardiomyopathy at a Teaching Hospital in North India. pubmed:28465969

International Journal of Cardiology

5-methoxytryptophan is a potential marker for post-myocardial infarction heart failure - apreliminary approach to clinical utility. pubmed:27526355

Cardiovasc Toxicol

Beneficial Effects of Ozone Therapy on Oxidative Stress, Cardiac Functions and Clinical Findings in Patients with Heart Failure Reduced Ejection Fraction pubmed:28097518

Sci Rep. 

Serial heart rhythm complexity changes in patients with anterior wall ST segment elevation myocardial infarction. pubmed:28252107

Journal of Cardiovascular Magnetic Resonance

The predictive capabilities of a novel cardiovascular magnetic resonance derived marker of cardiopulmonary reserve on established prognostic surrogate markers in patients with pulmonary vascular disease: results of a longitudinal pilot study pubmed:28065166

Repositório Institucional UNESP

AVALIAÇÃO ELETROCARDIOGRÁFICA AMBULATORIAL DE CÃES COM EHRLIQUIOSE MONOCÍTICA CRÔNICA handle:11449

Archivos de medicina veterinaria

Cardiac biomarkers in dogs with visceral leishmaniasis S0301-732X2016000300004

Original article

Evaluation of N-Terminal Pro Brain Natriuretic Peptide as a biomarker for clinical severity of heart failure in pediatric population Attach432

Evidence-Based Complementary and Alternative Medicine

Cardioprotection against Heart Failure by Shenfu Injection via TGF-β/Smads Signaling Pathway pubmed:28698735

Scientific Reports

QSKL protects against myocardial apoptosis on heart failure via PI3K/Akt-p53 signaling pathway. pubmed:29209026

Vascular Pharmacology

Reversal effects of low-dose imatinib compared with sunitinib on monocrotaline-induced pulmonary and right ventricular remodeling in rats pubmed:29100963

Evidence-based complementary and alternative medicine

Qiliqiangxin Enhances Cardiac Glucose Metabolism and Improves Diastolic Function in Spontaneously Hypertensive Rats pubmed:28706558

Europace

Prediction of electro-anatomical substrate using APPLE score and biomarkers Pubmed:29893827

Heart Rhythm

Role of NT-proANP and NT-proBNP in patients with atrial fibrillation: Association with atrial fibrillation progression phenotypes Pubmed:29604419

American Journal of Hypertension

MicroRNAs in Peripheral Mononuclear Cells as Potential Biomarkers in Hypertensive Patients With Heart Failure With Preserved Ejection Fraction Pubmed:29506053

International Journal of Molecular Medicine

Differential microRNA expression profiles and bioinformatics analysis between young and aging spontaneously hypertensive rats Pubmed:29328372

Biomarkers

Regulation of circulating chromogranin B levels in heart failure Pubmed:29098879

Lung

Effect of 6-min Walk Test on pro-BNP Levels in Patients with Pulmonary Arterial Hypertension Pubmed:29564533

International Journal of Clinical and Exp Medicine

Dynamic monitoring the level of NT-proBNP in assessing the value of cardiac function and prognosis in patients with systemic infection ijcem0072283.pdf

FASEB Journal

Signature-oriented investigation of the efficacy of multicomponent drugs against heart failure Pubmed: 30230922

International Journal of Clinical and Experimental Medicine

Qiliqiangxin ameliorates cardiac dysfunction in heart failure rats post myocardial infarction via activation of HIF/VEGF pathway

Pediatric Hematology Oncology Journal

Decreasing cardiac iron overload with Amlodipine and Spirulina in children with β-thalassemia Doi: 10.1016/j.phoj.2018.10.001

Journal of Clinical Medicine

Acute Responses of Novel Cardiac Biomarkers to a 24-h Ultra-Marathon Pubmed: 30625976

Van Veterinary Journal

Relationship between Natriuretic Peptide Levels with Heart and Kidney Parameters in Rats with Chronic Renal Failure.

Journal of Complementary and Integrative Medicine

Biological markers for the effects of yoga as a complementary and alternative medicine Pubmed: 30735481

Frontiers in Pharmacology

Trimetazidine Attenuates Exhaustive Exercise-Induced Myocardial Injury in Rats via Regulation of the Nrf2/NF-κB Signaling Pathway Pubmed: 30890937

Journal of Clinical Medicine

Potential Effects of CXCL9 and CCL20 on Cardiac Fibrosis in Patients with Myocardial Infarction and Isoproterenol-Treated Rats Pubmed: 31083544

PLoS One

Evaluation of heart rate variability and behavior of electrocardiographic parameters in dogs affected by chronic Monocytic Ehrlichiosis Pubmed: 31125348

Cardiovascular Research

Cardio-protective effect of the secretome of Sca-1+ and Sca-1-cells in heart failure–not equal, but equally important? Paracrine cell effects on heart failure

Advances in Medical Sciences

The potential role of inflammation in cryptogenic stroke

Disease Markers

Arterial Stiffness and Indices of Left Ventricular Diastolic Dysfunction in Patients with Embolic Stroke of Undetermined Etiology Pubmed: 31612072

Journal of Human Kinetics

Hormonal Response to Incremental and Continuous Exercise in Cyclists with Left Ventricle Hypertrophy Pubmed: 32148580

Nature Communications

Preclinical development of a miR-132 inhibitor for heart failure treatment Pubmed: 32005803

MEDIATORS OF INFLAMMATION

Evaluating the Relationship of GDF-15 with Clinical Characteristics, Cardinal Features, and Survival in Multiple Myeloma Pubmed: 33144847

EUROPEAN HEART JOURNAL

CDR132L improves systolic and diastolic function in a large animal model of chronic heart failure Pubmed: 33089304

REPRODUCTIVE TOXICOLOGY

Omega-3 polyunsaturated fatty acids alleviate hydrogen sulfide-induced blood-testis barrier disruption in the testes of adult mice Pubmed: 33068716

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Apela improves cardiac and renal function in mice with acute myocardial infarction Pubmed: 32686917

J Multidiscip Healthc

Left Ventricular Diastolic Dysfunction as Predictor of Unfavorable Prognosis After ESUS 33727824

Oxid Med Cell Longev

κ Opioid Receptor Agonist Inhibits Myocardial Injury in Heart Failure Rats through Activating Nrf2/HO-1 Pathway and Regulating Ca2+-SERCA2a 34373768

Biology

Hemodynamic Responses in Lower Limb Lymphedema Patients Undergoing Physical Therapy 34356497

Arch Acad Emerg Med

Risk Stratification of Pulmonary Thromboembolism using Brain Natriuretic Peptide and Troponin I; a Brief Report Pubmed:35072097

Transl Res

Interplay between mineral bone disorder and cardiac damage in acute kidney injury: from Ca2+ mishandling and preventive role of Klotho in mice to its potential … Pubmed:35077866

Medicina (Kaunas)

The Key Role of Hepcidin-25 in Anemia in Multiple Myeloma Patients with Renal Impairment Pubmed:35334593

Acta Cardiol Sin

Prothymosin α Gene Transfer Modulates Myocardial Remodeling after Ischemia-Reperfusion Injury Pubmed:35273440


Catalog No.

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