Cloud-clone
SKU:MAA979Hu21
Monoclonal Antibody to Cyclophilin A (CYPA)
Monoclonal Antibody to Cyclophilin A (CYPA)
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Western blotting: 0.5-5µg/mL
;Immunohistochemistry: 5-30µg/mL
;Immunocytochemistry: 5-30µg/mL
;Optimal working dilutions must be determined by end user.
Product No.
MAA979Hu21
Organism Species
Homo sapiens (Human).
Source
Monoclonal antibody preparation
Host
Mouse
Potency (Clone Number)
C1
Ig Isotype
IgG2a Kappa
Purification
Protein A + Protein G affinity chromatography
Label
None
Immunogen
RPA979Hu01-Recombinant Cyclophilin A (CYPA)
Buffer Formulation
0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Traits
Liquid
Concentration
1mg/ml
Organism Species More
Sus scrofa; Porcine (Pig)
Applications
WB,IHC
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a mouse monoclonal antibody raised against CYPA. It has been selected for its ability to recognize CYPA in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.01-2µg/mL；
Immunohistochemistry: 5-30µg/mL；
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Atherosclerosis | EMMPRIN and its ligand cyclophilin A regulate MT1-MMP, MMP-9 and M-CSF during foam cell formation PubMed: 19758589 |
| Biomarkers | Cyclophilin-A: a novel biomarker for untreated male essential hypertension Pubmed: 24164594 |
| Cardiovascular Diabetology | Plasma level of cyclophilin A is increased in patients with type 2 diabetes mellitus and suggests presence of vascular disease Pubmed:24502618 |
| International Journal of Biological Sciences | Decrease in Plasma Cyclophilin A Concentration at 1 Month after Myocardial Infarction Predicts Better Left Ventricular Performance and Synchronicity at 6 Months: A Pilot Study in Patients with ST Elevation Myocardial Infarction Pubmed:25552928 |
| Medicine | Cyclophilin A in Ruptured Intracranial Aneurysm PubMed: 26426668 |
| Mol Cell Biochem | PPIA rs6850: A> G single-nucleotide polymorphism is associated with raised plasma cyclophilin A levels in patients with coronary artery disease PubMed: 26702934 |
| Medicine (Baltimore) | Urinary Cyclophilin A as a New Marker for Diabetic Nephropathy: A Cross-Sectional Analysis of Diabetes Mellitus PubMed: 26496315 |
| International Journal of Cardiology | Cyclophilin A modulates bone marrow-derived CD117(+) cells and enhances ischemia-induced angiogenesisvia the SDF-1/CXCR4 axis. Pubmed:27057951 |
| Clinica Chimica Acta | Novel findings of secreted cyclophilin A in diabetic nephropathy and its association with renal protection of dipeptidyl peptidase 4 inhibitor pubmed:27823952 |
| Cardiovascular Diabetology | Cyclophilin A enhances macrophage differentiation and lipid uptake in high glucose conditions: a cellular mechanism for accelerated macro vascular disease in diabetes mellitus. pubmed:27809851 |
| Clinical Science | Metformin attenuates effects of cyclophilin A on macrophages, reduces lipid uptake and secretion of cytokines by repressing decreased AMPK activity Pubmed:29382697 |
| Journal of Molecular Histology | Cyclophilin a increases CD68 cell infiltration in rat experimental periodontitis Pubmed:29318411 |
| Free Radical Research | Cyclophilin A and CD147 associate with progression of diabetic nephropathy Pubmed: 30572748 |
| The Kaohsiung Journal of Medical Sciences | Association of cyclophilin A level and pulse pressure in predicting recurrence of cerebral infarction Pubmed: 31670477 |
| Cells. | Cyclophilin A/EMMPRIN Axis Is Involved in Pro-Fibrotic Processes Associated with Thoracic Aortic Aneurysm of Marfan Syndrome Patients Pubmed: 31936351 |
| JAMA Neurology | APPENDIX A: Relationship between cyclophilin A levels and matrix metalloproteinase-9 activity in cerebrospinal fluid of cognitively normal apolipoprotein E4 carriers … Pubmed: 24030206 |
| Menoufia Medical Journal | Urinary podocalyxin and cyclophilin A: markers for early detection of type 2 diabetic nephropathy |
| Toxins | Evaluation of the Therapeutic Effects of Protocatechuic Aldehyde in Diabetic Nephropathy 34437430 |
| Cell Death & Disease | Proteomic analysis reveals USP7 as a novel regulator of palmitic acid-induced hepatocellular carcinoma cell death Pubmed:35732625 |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| RPA979Hu01 | Recombinant Cyclophilin A (CYPA) | Positive Control; Immunogen; SDS-PAGE; WB. |
| CPA979Hu21 | OVA Conjugated Cyclophilin A (CYPA) | Immunogen; SDS-PAGE; WB. |
| PAA979Hu08 | Polyclonal Antibody to Cyclophilin A (CYPA) | WB; IHC; ICC; IP. |
| PAA979Hu01 | Polyclonal Antibody to Cyclophilin A (CYPA) | WB; IHC; ICC; IP. |
| LAA979Hu81 | FITC-Linked Polyclonal Antibody to Cyclophilin A (CYPA) | WB; IHC; ICC; IF. |
| LAA979Hu71 | Biotin-Linked Polyclonal Antibody to Cyclophilin A (CYPA) | WB; IHC; ICC. |
| MAA979Hu22 | Monoclonal Antibody to Cyclophilin A (CYPA) | WB,IHC,ICC/IF |
| MAA979Hu23 | Monoclonal Antibody to Cyclophilin A (CYPA) | WB; IHC; ICC; IP. |
| MAA979Hu21 | Monoclonal Antibody to Cyclophilin A (CYPA) | WB,IHC |
| LAA979Hu72 | Biotin-Linked Monoclonal Antibody to Cyclophilin A (CYPA) | WB; IHC; ICC. |
| SEA979Hu | ELISA Kit for Cyclophilin A (CYPA) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA979Hu | Magnetic Luminex Assay Kit for Cyclophilin A (CYPA) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
| PSA979Hu01 | Antibody Pair for Cyclophilin A (CYPA) | ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays. |
| KSA979Hu01 | ELISA Kit DIY Materials for Cyclophilin A (CYPA) | Main materials for "Do It (ELISA Kit) Yourself". |
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