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SKU:PAA570Hu01
Polyclonal Antibody to Procollagen I C-Terminal Propeptide (PICP)
Polyclonal Antibody to Procollagen I C-Terminal Propeptide (PICP)
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Western blotting: 0.5-2µg/mL;1:500-2000
;Immunohistochemistry: 5-20µg/mL;1:50-200
;Immunocytochemistry: 5-20µg/mL;1:50-200
;Optimal working dilutions must be determined by end user.
Product No.
PAA570Hu01
Organism Species
Homo sapiens (Human).
Source
Polyclonal antibody preparation
Host
Rabbit
Potency
n/a
Ig Type
IgG
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Label
None
Immunogen
CPA570Hu21-OVA Conjugated Procollagen I C-Terminal Propeptide (PICP)
Buffer Formulation
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Traits
Liquid
Concentration
0.5mg/ml
Organism Species More
Mus musculus (Mouse)
Applications
WB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against PICP. It has been selected for its ability to recognize PICP in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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Magazine |
Citations |
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Nutrition |
Dyslipidemic high-fat diet affects adversely bone metabolism in mice associated with impaired antioxidant capacity ScienceDirect: S0899900709004717 |
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American Heart Journal |
Serum markers of deranged myocardial collagen turnover: their relation to malignant ventricular arrhythmias in cardioverter-defibrillator recipients with heart failure. PubMed: 23067911 |
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Journal of Hypertension |
Circulating biomarkers of collagen metabolism in arterial hypertension: relevance of target organ damage Pubmed: 23615327 |
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Pancreatology |
Cdkn1a is a key mediator of rat pancreatic stellate cell senescence Pubmed: 23719597 |
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The American Journal of Cardiology |
Relation of burden of myocardial fibrosis to malignant ventricular arrhythmias and outcomes in Fabry disease Pubmed:25073565 |
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PLoS One. |
An NMR Metabolomic Study on the Effect of Alendronate in Ovariectomized Mice Pubmed:25184758 |
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Journal of Bone and Mineral Research |
The Anti-Osteoanabolic Function of Sclerostin is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5 Pubmed:25640331 |
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Bone |
The active role of osteoporosis in the interaction between osteoblasts and bone metastases PubMed: 26057367 |
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J Nutr Biochem |
Consumption of vitamin D2 PubMed: 25792284 |
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Bibliothekssystem Universität Hamburg |
Bilaterale Kommunikation zwischen Osteoblasten und Osteoklasten volltexte:2016 |
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Inflammation Research |
Fibrosis of extracellular matrix is related to the duration of the disease but is unrelated to the dynamics of collagen metabolism in dilated cardiomyopathy pubmed:27516211 |
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Heart & Vessels |
Left ventricular reverse remodeling is not related to biopsy-detected extracellular matrix fibrosis and serum markers of fibrosis in dilated cardiomyopathy, regardless of the definition used for LVRR pubmed:28004175 |
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Scandinavian Journal of Rheumatology |
The association between insulin-like growth factor 1 (IGF-1), IGF-binding proteins (IGFBPs), and the carboxyterminal propeptide of type I procollagen (PICP) in pre- and postmenopausal women with rheumatoid arthritis. pubmed:27775453 |
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Allergy and Asthma Proceedings |
Effect of montelukast on markers of airway remodeling in children withasthma. pubmed:27657514 |
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Scandinavian Journal of Rheumatology |
The association between insulin-like growth factor 1 (IGF-1), IGF-binding proteins (IGFBPs), and the carboxyterminal propeptide of type I procollagen (PICP) in pre- and postmenopausal women with rheumatoid arthritis loi:irhe20 |
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Conditional Mouse Models Support the Role of SLC39A14 (ZIP14) in Hyperostosis Cranialis Interna and in Bone Homeostasis ISBN: 978-94-6299-582-6 |
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MOLECULAR MEDICINE REPORTS |
Endothelial‑to‑mesenchymal transition in human idiopathic dilated cardiomyopathy pubmed:29115553 |
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Pediatrics and Neonatology |
Age-related changes in biochemical bone profile in thalassemic children pubmed:28967496 |
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Heart and Vessels |
Left ventricular reverse remodeling is not related to biopsy‑detected extracellular matrix fibrosis and serum markers of fibrosis in dilated cardiomyopathy, regardless of the definition used for LVRR 10.1007/s00380-016-0930-y |
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Journal of Bone and Mineral Research |
The Lrp4 R1170Q homozygous knock‐in mouse recapitulates the bone phenotype of sclerosteosis in humans pubmed:28477420 |
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Cytokine |
12-month patterns of serum markers of collagen synthesis, transforming growth factor and connective tissue growth factor are similar in new-onset and chronic dilated cardiomyopathy in patients both with and without cardiac fibrosis. pubmed:28460256 |
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Advanced Healthcare Materials |
Prognostic value of fibrosis-related markers in dilated cardiomyopathy: A link between osteopontin and cardiovascular events. pubmed:29120858 |
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Journal of Bone and Mineral Metabolism |
Mutations That Alter the Carboxy‐Terminal‐Propeptide Cleavage Site of the Chains of Type I Procollagen Are Associated With a Unique Osteogenesis Imperfecta … Pubmed:29669177 |
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Cardiovascular Journal of Africa |
Assessment of myocardial fibrosis by late gadolinium enhancement imaging and biomarkers of collagen metabolism in chronic rheumatic mitral regurgitation. Pubmed:29443354 |
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Journal of Cellular Physiology |
DNA methylation regulates α‐smooth muscle actin expression during cardiac fibroblast differentiation Pubmed: 30362530 |
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International Journal of Chronic Obstructive Pulmonary Disease |
Altered serum levels of type I collagen turnover indicators accompanied by IL-6 and IL-8 release in stable COPD Pubmed: 30655663 |
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Scientific Reports |
Low fibrosis biomarker levels predict cardiac resynchronization therapy response Pubmed: 30988339 |
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Bone |
Agonist-induced activation of the S1P receptor 2 constitutes a novel osteoanabolic therapy for the treatment of osteoporosis in mice Pubmed: 31028959 |
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PLoS One |
Deficiency of sphingosine-1-phosphate receptor 3 does not affect the skeletal phenotype of mice lacking sphingosine-1-phosphate lyase Pubmed: 31314788 |
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Bone |
Mice lacking plastin-3 display a specific defect of cortical bone acquisition Pubmed: 31678489 |
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Journal of Diabetes Research |
Type 2 Diabetes Mellitus and Chronic Heart Failure with Midrange and Preserved Ejection Fraction: A Focus on Serum Biomarkers of Fibrosis Pubmed: 33224989 |
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JOURNAL OF BONE AND MINERAL RESEARCH |
Piezo1 Inactivation in Chondrocytes Impairs Trabecular Bone Formation Pubmed: 33180356 |
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Microbiome changes in patients with chronic heart failure with preserved ejection fraction correlate with fibrosis markers: Description of a Russian cohort |
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Ассоциации толщины эпикардиального жира и циркулирующих маркеров фиброза миокарда у пациентов с инфарктом миокарда |
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Russian Journal of Cardiology |
Early diagnosis of myocardial fibrosis in patients with epicardial obesity |
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J Diabetes Res |
Association between Markers of Fibrosis and Heart Failure Incidence in Patients with Type 2 Diabetes Mellitus 34778465 |
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Clinical, Cosmetic and Investigational Dermatology |
Extra Cellular Matrix Deposition and Assembly in Dermis Spheroids 34321901 |
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Scandinavian Cardiovascular Journal |
Dual integrin αvβ3 and αvβ5 blockade attenuates cardiac dysfunction by reducing fibrosis in a rat model of doxorubicin-induced cardiomyopathy 34296634 |
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Eur J Appl Physiol |
Effects of 8-week increment aerobic exercise program on bone metabolism and body composition in young non-athletes Pubmed:35141785 |
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J. Clin. Med |
Simple Predictors for Cardiac Fibrosis in Patients with Type 2 Diabetes Mellitus: The Role of Circulating Biomarkers and Pulse Wave Velocity Pubmed:35628969 |
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