Cloud-clone
SKU:MAB280Hu21
Monoclonal Antibody to Cathepsin D (CTSD)
Monoclonal Antibody to Cathepsin D (CTSD)
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Western blotting: 0.2-2µg/mL;1:500-5000
Immunohistochemistry: 5-20µg/mL;1:50-200
Immunocytochemistry: 5-20µg/mL;1:50-200
Optimal working dilutions must be determined by end user.
Product No.
MAB280Hu21
Organism Species
Homo sapiens (Human).
Source
Monoclonal antibody preparation
Host
Mouse
Potency (Clone Number)
C11
Ig Isotype
IgG2b Kappa
Purification
Protein A + Protein G affinity chromatography
Label
None
Immunogen
EPB280Hu61-Eukaryotic Cathepsin D (CTSD)
Buffer Formulation
0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Traits
Liquid
Concentration
1mg/mL
Organism Species More
n/a
Applications
WB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a mouse monoclonal antibody raised against CTSD. It has been selected for its ability to recognize CTSD in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.5-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Molecular Immunology | Cathepsin D is released after severe tissue trauma in vivo and is capable of generating C5a in vitro ScienceDirect: S0161589011008297 |
| 21 | Plasma Cathepsin D Levels: A Novel Tool to Predict Pediatric Hepatic Inflammation PubMed: 25732418 |
| Scientific Reportes | Plasma cathepsin D correlates with histological classifications of fatty liver disease in adults and responds to intervention pubmed:27922112 |
| Biomedicine & pharmacotherapy | Berberine ameliorates intrahippocampal kainate-induced status epilepticus and consequent epileptogenic process in the rat: Underlying mechanisms pubmed:28061403 |
| JGH OPEN | Limited applicability of cathepsin D for the diagnosis and monitoring of non‐alcoholic steatohepatitis |
| Diabetologia | Plasma cathepsin D activity is negatively associated with hepatic insulin sensitivity in overweight and obese humans Pubmed: 31690989 |
| Antioxidants | Iron and Advanced Glycation End Products: Emerging Role of Iron in Androgen Deficiency in Obesity Pubmed: 32235809 |
| Peptides | LVV-hemorphin-7 (LVV-H7) plays a role in antinociception in a rat model of alcohol-induced pain disorders 33253777 |
| Cells | Identification of Cathepsin D as a Plasma Biomarker for Alzheimer's Disease 33445607 |
| J Chem Neuroanat | Analysis of silymarin-modulating effects against acrylamide-induced cerebellar damage in male rats: Biochemical and pathological markers 33965515 |
| Front Cell Infect Microbiol | PGRS Domain of Rv0297 of Mycobacterium tuberculosis Is Involved in Modulation of Macrophage Functions to Favor Bacterial Persistence 33042856 |
| Nutr Metab Cardiovasc Dis | Serum CathepsinD in pregnancy: relation with metabolic and inflammatory markers and effects of fish oils and probiotics Pubmed:35304048 |
| Biosensors | A Comparison of Various Chips Used for the Manufacture of Biosensors Applied in Non-Fluidic Array SPRi, Based on the Example of Determination of Cathepsin D Pubmed:35049649 |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| APB280Hu61 | Active Cathepsin D (CTSD) | Cell culture; Activity Assays. |
| EPB280Hu61 | Eukaryotic Cathepsin D (CTSD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB280Hu01 | Recombinant Cathepsin D (CTSD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPB280Hu62 | Eukaryotic Cathepsin D (CTSD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB280Hu02 | Recombinant Cathepsin D (CTSD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB280Hu03 | Recombinant Cathepsin D (CTSD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB280Hu04 | Recombinant Cathepsin D (CTSD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB280Hu02 | Polyclonal Antibody to Cathepsin D (CTSD) | WB; IHC; ICC; IP. |
| PAB280Hu01 | Polyclonal Antibody to Cathepsin D (CTSD) | WB; IHC; ICC; IP. |
| LAB280Hu71 | Biotin-Linked Polyclonal Antibody to Cathepsin D (CTSD) | WB; IHC; ICC. |
| MAB280Hu21 | Monoclonal Antibody to Cathepsin D (CTSD) | WB; IHC; ICC; IP. |
| MAB280Hu26 | Monoclonal Antibody to Cathepsin D (CTSD) | WB; IHC; ICC; IP. |
| MAB280Hu22 | Monoclonal Antibody to Cathepsin D (CTSD) | WB; IHC; ICC; IP. |
| SEB280Hu | ELISA Kit for Cathepsin D (CTSD) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| HEB280Hu | High Sensitive ELISA Kit for Cathepsin D (CTSD) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB280Hu | Magnetic Luminex Assay Kit for Cathepsin D (CTSD) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
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