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SKU:MAC559Hu21

Monoclonal Antibody to Kisspeptin 1 (KISS1)

Monoclonal Antibody to Kisspeptin 1 (KISS1)

Regular price $380.00 USD
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UOM
Concentration
Organism species

Western blotting: 0.5-2µg/mL;
;Immunohistochemistry: 5-20µg/mL;
;Immunocytochemistry: 5-20µg/mL;
;Optimal working dilutions must be determined by end user.

Product No.

MAC559Hu21

Organism Species

Homo sapiens (Human).

Source

Monoclonal antibody preparation

Host

Mouse

Potency (Clone Number)

C1

Ig Isotype

IgG1 Kappa

Purification

Protein A + Protein G affinity chromatography

Label

None

Immunogen

RPC559Hu01-Recombinant Kisspeptin 1 (KISS1)

Buffer Formulation

0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Traits

Liquid

Concentration

1mg/mL

Organism Species More

n/a

Applications

WB; IHC; ICC; IP.

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a mouse monoclonal antibody raised against KISS1. It has been selected for its ability to recognize KISS1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine Citations
Mol Endocrinol. LIM-homeodomain transcription factor Isl-1 mediates kisspeptin's effect on insulin secretion in mice. Pubmed:24956377
临床儿科杂志 双酚A 与女童性早熟的关系 Fileup: Pdf
J Pediatr Endocrinol Metab The relation of urinary bisphenol A with kisspeptin in girls diagnosed with central precocious puberty and premature thelarche PubMed: 26565542
Archives of Physiology and Biochemistry Circulating levels of leptin, nesfatin-1 and kisspeptin in postmenopausal obese women Pubmed:27011110
International Journal of Endocrinology The Changes of Serum Leptin and Kisspeptin Levels in Chinese Children and Adolescents in Different Pubertal Stages pubmed:27990162
Journal of Clinical Research in Pediatric Endocrinology Basal Serum Neurokinin B Levels in Differentiating Idiopathic Central Precocious Puberty from Premature Thelarche. pubmed:28008860
BioMed Research International Kisspeptin Protein in Seminal Plasma Is Positively Associated with Semen Quality: Results from the MARHCS Study in Chongqing, China
OBESITY SURGERY Lack of Improvement of Sperm Characteristics in Obese Males After Obesity Surgery Despite the Beneficial Changes Observed in Reproductive Hormones Pubmed: 30806913
International Journal of Endocrinology Serum Kisspeptin and Its Relation to Metabolic Parameters and Glucose Metabolism in Prepubertal and Pubertal Obese Children Pubmed: 33224197
journal of reproduction and fertility KISS1R Signaling Modulates Gonadotropin Sensitivity in Mouse Leydig Cell Pubmed: 33112765
Beyond GnRH, LH and FSH: the role of kisspeptin on hypothalalmic-3 pituitary gonadal (HPG) axis pathology and diagnostic consideration 4
Medeni Med J Kisspeptin and Hematologic Parameters as Predictive Biomarkers for First-Trimester Abortions 34239761
Arch Gynecol Obstet Comparison of the Kisspeptin levels in early onset preeclampsia and late-onset preeclampsia Pubmed:35039882
J Pediatr Endocrinol Metab Serum kisspeptin, leptin, neuropeptide Y, and neurokinin B levels in adolescents with polycystic ovary syndrome Pubmed:35170267
Genes Differential Expression of Kisspeptin System and Kisspeptin Receptor Trafficking during Spermatozoa Transit in the Epididymis Pubmed:35205340
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