Cloud-clone
SKU:RPA006Bo01
Recombinant Amphiregulin (AREG)
Recombinant Amphiregulin (AREG)
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Prokaryotic expression
Product No.
RPA006Bo01
Organism Species
Bos taurus; Bovine (Cattle).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Membrane
Predicted Molecular Mass
54.8kDa
Accurate Molecular Mass
60kDa(Analysis of differences refer to the manual)
Residues & Tags
Leu27~Ala247 with N-terminal His and GST Tag
Buffer Formulation
PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Traits
Freeze-dried powder
Purity
> 97%
Isoelectric Point
8.17
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Onkologie | Amphiregulin and Epiregulin Expression in Colorectal Carcinoma and the Correlation with Clinicopathological Characteristics Karger: 315380 |
| Br J Cancer. | Serum levels of hepatocyte growth factor and epiregulin are associated with the prognosis on anti-EGFR antibody treatment in KRAS wild-type metastatic colorectal cancer. Pubmed:24800946 |
| Cancer Sci | Association between serum ligands and the skin toxicity of anti-epidermal growth factor receptor antibody in metastatic colorectal cancer PubMed: 25707609 |
| J Cancer Res Clin Oncol | Amphiregulin confers trastuzumab resistance via AKT and ERK activation in HER2-positive breast cancer PubMed: 26195282 |
| Oncotarget. | Serum level of hepatocyte growth factor is a novel marker of predicting theoutcome and resistance to the treatment with trastuzumab in HER2-positive patients with metastatic gastric cancer Pubmed:26716644 |
| Acta Pharmacologica Sinica | Anti-asthmatic activity of alkaloid compounds from Pericarpium Citri Reticulatae (Citrus reticulata 'Chachi') Pubmed: 19363516 |
| International Journal of Biological Sciences | CD9 regulates keratinocyte migration by negatively modulating the sheddase activity of ADAM17 |
| Neoplasia | Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine Pubmed: 33212364 |
| JOURNAL OF CELLULAR AND MOLECULAR MEDICINE | Polarization of ADAM17‐driven EGFR signalling in electric field‐guided collective migration of epidermal sheets Pubmed: 33164313 |
| Catalog No. | Related products for research use of Bos taurus; Bovine (Cattle) Organism species | Applications (RESEARCH USE ONLY!) |
| RPA006Bo01 | Recombinant Amphiregulin (AREG) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA006Bo01 | Polyclonal Antibody to Amphiregulin (AREG) | WB; IHC; ICC; IP. |
| MAA006Bo21 | Monoclonal Antibody to Amphiregulin (AREG) | WB; IHC; ICC; IP. |
| SEA006Bo | ELISA Kit for Amphiregulin (AREG) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCA006Bo | CLIA Kit for Amphiregulin (AREG) | Chemiluminescent immunoassay for Antigen Detection. |
| LMA006Bo | Magnetic Luminex Assay Kit for Amphiregulin (AREG) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
| PGA006Bo01 | Primer Pair for Amphiregulin (AREG) | PCR |
| CGA006Bo01 | cDNA of Amphiregulin (AREG) | PCR; Protein Expression; etc. |
