Cloud-clone
SKU:RPA705Ra01
Recombinant Mucin 2 (MUC2)
Recombinant Mucin 2 (MUC2)
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Prokaryotic expression
Product No.
RPA705Ra01
Organism Species
Rattus norvegicus (Rat).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Secreted
Predicted Molecular Mass
66.7kDa
Accurate Molecular Mass
70kDa(Analysis of differences refer to the manual)
Residues & Tags
Val33~Ala601 with N-terminal His Tag
Buffer Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Traits
Freeze-dried powder
Purity
> 90%
Isoelectric Point
4.9
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Annals of surgical oncology | Pancreatic cyst fluid and serum mucin levels predict dysplasia in intraductal papillary mucinous neoplasms of the pancreas. PubMed: 20717734 |
| World J Gastroenterol. | Sodium alginate ameliorates indomethacin-induced gastrointestinal mucosal injury via inhibiting translocation in rats. Pubmed:24627600 |
| Front Microbiol | Fecal microbiota transplantation and bacterial consortium transplantation have comparable effects on the re-establishment of mucosal barrier function in mice with intestinal dysbiosis PubMed: 26217323 |
| nutrition research and practice | Butyrate modulates bacterial adherence on LS174T human colorectal cells by stimulating mucin secretion and MAPK signaling pathway PubMed: 26244071 |
| Respirology | Secreted mucins and airway bacterial colonization in non-CF bronchiectasis PubMed: 26172851 |
| Ann Am Thorac Soc | Airway Mucin 2 Is Decreased in Patients with Severe Chronic Obstructive Pulmonary Disease with Bacterial Colonization doi:10.1513 |
| Cellular Microbiology | An adherent mucus layer attenuates the genotoxic effect of colibactin. pubmed:29156489 |
| Bio-protocol | Enhancement of Mucus Production in Eukaryotic Cells and Quantification of Adherent Mucus by ELISA 10.21769:BioProtoc.2879 |
| Journal of Investigative Medicine | The characteristics and clinical significance of mucin levels in bronchoalveolar lavage fluid of patients with interstitial lung disease Pubmed: 30573494 |
| Biomolecules | Clinical Significance of Serum Membrane-Bound Mucin-2 Levels in Breast Cancer Pubmed: 30682816 |
| Cell Stem Cell | PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism Pubmed: 31564549 |
| DIGESTIVE DISEASES AND SCIENCES | Compromised Ileal Mucus Barrier Due to Impaired Epithelial Homeostasis Caused by Notch1 Signaling in Cirrhotic Rats Pubmed: 32144600 |
| Scientific Reports | Mucus layer modeling of human colonoids during infection with enteroaggragative E. coli Pubmed: 32601325 |
| Biorxiv | Defective intestinal repair after short-term high fat diet due to loss of efferocytosis |
| J Cell Mol Med | Inhibition of cyclooxygenase©\2 enhanced intestinal epithelial homeostasis via suppressing ¦Â©\catenin signalling pathway in experimental liver fibrosis 34145945 |
| Cell Tissue Res | Reduced acetylcholine and elevated muscarinic receptor 2 in duodenal mucosa contribute to the impairment of mucus secretion in 6-hydroxydopamine-induced … 34370080 |
| Catalog No. | Related products for research use of Rattus norvegicus (Rat) Organism species | Applications (RESEARCH USE ONLY!) |
| RPA705Ra02 | Recombinant Mucin 2 (MUC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA705Ra01 | Recombinant Mucin 2 (MUC2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA705Ra01 | Polyclonal Antibody to Mucin 2 (MUC2) | WB; IHC; ICC; IP. |
| MAA705Ra21 | Monoclonal Antibody to Mucin 2 (MUC2) | WB; IHC; ICC; IP. |
| SEA705Ra | ELISA Kit for Mucin 2 (MUC2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA705Ra | Magnetic Luminex Assay Kit for Mucin 2 (MUC2) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
