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SKU:RPA746Ra01

Recombinant Fibroblast Growth Factor 23 (FGF23)

Recombinant Fibroblast Growth Factor 23 (FGF23)

Regular price $510.00 USD
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UOM
Purity
Organism species

Prokaryotic expression

Product No.

RPA746Ra01

Organism Species

Rattus norvegicus (Rat).

Source

Prokaryotic expression

Host

E.coli

Endotoxin Level

<1.0EU per 1µg (determined by the LAL method)

Subcellular Location

Secreted

Predicted Molecular Mass

29.1kDa

Accurate Molecular Mass

31kDa(Analysis of differences refer to the manual)

Residues & Tags

Tyr25~Val251 with N-terminal His Tag

Buffer Formulation

20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Traits

Freeze-dried powder

Purity

> 90%

Isoelectric Point

10.0

Applications

Positive Control; Immunogen; SDS-PAGE; WB.

If bio-activity of the protein is needed, please check active protein.

UOM

20µl 100µl 200µl 1ml 10ml

SEQUENCE

 

 

 

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine

Citations

Journal of international medicine

Prognostic impact of renal function in precapillary pulmonary hypertension Pubmed: 24011362

BMC Nephrology

FGF-23 associated with the progression of coronary artery calcification in hemodialysis patients Pubmed: 24180481

Journal of Clinical Densitometry

Lower Fibroblast Growth Factor 23 Levels in Young Adults With Crohn Disease as a Possible Secondary Compensatory Effect on the Disturbance of Bone and Mineral Metabolism Pubmed: 23623649

J Intern Med.

Prognostic impact of renal function in precapillary pulmonary hypertension. Pubmed:24011362

Journal of Bone and Mineral Research

Adverse effects of osteocytic constitutive activation of ?-catenin on bone strength and bone growth Pubmed:25639729

Nefrologia

Fibroblast growth factor is associated to left ventricular mass index, anemia and low values of transferrin saturation El factor de crecimiento fibroblástico está asociado con el índice de masa ventricular izquierda, anemia y niveles bajos de saturación de la transferrina PubMed: 26394828

Medicine (Baltimore)

An Attempt to Evaluate Selected Aspects of “Bone–Fat Axis” Function in Healthy Individuals and Patients With Pancreatic Cancer PubMed: 26266370

Ann Biol Clin (Paris)

Les biomarqueurs des calcifications vasculaires: quelles limites analytiques pour leur transfert de la recherche bioclinique à la pratique? PubMed: 26069069

Scandinavian Journal of Gastroenterology

High-dose fast infusion of parenteral iron isomaltoside is efficacious in inflammatory bowel disease patients with iron-deficiency anaemia without profound changes in phosphate or fibroblast growth factor 23 Pubmed:27326766

PLOS ONE

Prostaglandin-E2 Mediated Increase in Calcium and Phosphate Excretion in a Mouse Model ofDistal Nephron Salt Wasting. pubmed:27442254

Journal of Laboratory Diagnostics

Evaluation of concentration fibroblast growth factor FGF-23 in hemodialysed patients and after kidney transplantation publication:312592751

Journal of Integrative Nephrology & Andrology

Associations between serum fibroblast growth factor 23 level and intradialytic hypotension in hemodialysis patients issn:2394-2916

Journal of Renal Nutrition

ADAM17, a New Player in the Pathogenesis of Chronic Kidney Disease-Mineral and Bone Disorder. pubmed:29056164

Experimental Biology and Medicine(Maywood)

Effect of cross-linked chitosan iron (III) on vascular calcification in uremic rats Pubmed:29763365

Psychiatry Research

Cerebrospinal fluid FGF23 levels correlate with a measure of impulsivity Pubmed:29677623

BMC Pediatrics

Serum and urine FGF23 and IGFBP-7 for the prediction of acute kidney injury in critically ill children Pubmed:29907141

Medical Science Monitor

Effect of Salt Intervention on Serum Levels of Fibroblast Growth Factor 23 (FGF23) in Chinese Adults: An Intervention Study Pubmed:29608553

International Journal of Chronic Obstructive Pulmonary Disease

Disconnection of pulmonary and systemic arterial stiffness in COPD Pubmed:29881265

Saudi journal of kidney diseases and transplantation

Prevalence of cardiac arrhythmia and risk factors in chronic kidney disease patients Pubmed:29970732

Nephrology Dialysis Transplantation

High-serum phosphate and parathyroid hormone distinctly regulate bone loss and vascular calcification in experimental chronic kidney disease Pubmed: 30189026

BioFactors 

Alteration in serum concentrations of FGF19, FGF21, and FGF23 in patients with urothelial carcinoma Pubmed: 30334297

Biological Trace Element Research

Altered Mineral Metabolism and Disequilibrium Between Calcification Promoters and Inhibitors in Chronic Hemodialysis Patients Pubmed: 30847765

Clin Implant Dent Relat Res.

Evaluation of FGF‐23 and 25(OH)D3 levels in peri‐implant sulcus fluid in peri‐implant health and diseases Pubmed: 31407857

JACC-Cardiovascular Imaging

PREVALANCE AND PROGRESSION OF CARDIOVASCULAR CALCIFICATIONS IN HAEMODIALYSIS PATIENTS Pubmed: 28797410

Saudi J Kidney Dis Transpl

Serum fibroblast growth factor 23 levels do not correlate with carotid intima-media thickness in patients with chronic kidney disease Pubmed: 31696838

Biomedicine & Pharmacotherapy

MiRNA-192-5p attenuates airway remodeling and autophagy in asthma by targeting MMP-16 and ATG7 Pubmed: 31918268


Is Serum FGF-23 Associated with Subclinic Atherosclerosis in Patients with AA Amyloidosis?


THE RELATIONSHIP BETWEEN ARTERIAL STIFNESS AND 25-(OH) VITAMIN D, FGF 23 IN MAINTENANCE HEMODIALYSIS PATIENTS


THE RELATIONSHIP BETWEEN ARTERIAL STIFFNESS AND 25-(OH) VITAMIN D, FGF 23 IN MAINTENANCE HEMODIALYSIS PATIENTS KRON?K ¡­

Calcif Tissue Int

The Measurement and Interpretation of Fibroblast Growth Factor 23 (FGF23) Concentrations Pubmed:35665817

European Journal of Medical Genetics

Genetic and clinical profile of patients with hypophosphatemic rickets Pubmed:35738466

African Health Sciences

Fibroblast Growth Factor 23 (FGF 23) and intact parathyroid hormone (iPTH) as markers of mineral bone disease among Nigerians with non-diabetic kidney disease


Catalog No.

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