Cloud-clone
SKU:RPA777Hu01
Recombinant Inducible T-Cell Co Stimulator (ICOS)
Recombinant Inducible T-Cell Co Stimulator (ICOS)
Couldn't load pickup availability
Prokaryotic expression
Product No.
RPA777Hu01
Organism Species
Homo sapiens (Human).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Membrane, Secreted
Predicted Molecular Mass
48.1kDa
Accurate Molecular Mass
48kDa(Analysis of differences refer to the manual)
Residues & Tags
Phe31~Lys190 with N-terminal His and GST Tag
Buffer Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Traits
Freeze-dried powder
Purity
> 90%
Isoelectric Point
8.3
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Archives of Dermatological Research | Increased production of soluble inducible costimulator in patients with diffuse cutaneous systemic sclerosis Pubmed: 23053221 |
| DNA Cell Biol. | Effect of soluble inducible costimulator level and its polymorphisms on age-related macular degeneration. Pubmed: 24083358 |
| Rheumatology | Augmented ICOS expression in patients with early diffuse cutaneous systemic sclerosis Pubmed: 23024058 |
| Br J Haematol | Inducible T‐cell co‐stimulator (ICOS) and ICOS ligand are novel players in the multiple‐myeloma microenvironment Pubmed:34954822 |
| Diagnostics (Basel) | Increased Levels of ICOS and ICOSL Are Associated to Pulmonary Arterial Hypertension in Patients Affected by Connective Tissue Diseases Pubmed:35328257 |
