Cloud-clone
SKU:RPA853Hu01
Recombinant Caspase 8 (CASP8)
Recombinant Caspase 8 (CASP8)
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Prokaryotic expression
Product No.
RPA853Hu01
Organism Species
Homo sapiens (Human).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Cytoplasm
Predicted Molecular Mass
22.8kDa
Accurate Molecular Mass
25kDa(Analysis of differences refer to the manual)
Residues & Tags
Ser217~Asp384 with N-terminal His Tag
Buffer Formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Traits
Freeze-dried powder
Purity
> 97%
Isoelectric Point
6.0
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Molecular Neurobiology | Ursodeoxycholic Acid Ameliorates Apoptotic Cascade in the Rotenone Model of Parkinson’s Disease: Modulation of Mitochondrial Perturbations Pubmed:25502462 |
| Journal of Ethnopharmacology | Viscum articulatum Burm. f. aqueous extract exerts antiproliferative effect and induces cell cycle arrest and apoptosis in leukemia cells Pubmed:29555410 |
| Clinical And Experimental Pharmacology And Physiology | Diallyl sulfide alleviates cisplatin‐induced nephrotoxicity in rats via suppressing NF‐κB downstream inflammatory proteins and p53/Puma signalling pathway Pubmed:29266336 |
| Environmental Toxicology | Antihepatocarcinogenic activity of whey protein concentrate and lactoferrin in diethylnitrosamine‐treated male albino mice Pubmed: 31087429 |
| Environ Toxicol Pharmacol. | Targetingp53/TRAIL/caspase-8 signaling by adiponectin reverses thioacetamide-induced hepatocellular carcinoma in rats Pubmed: 31421311 |
| Journal of Biochemical and Molecular Toxicology | Tranilast attenuates methotrexate‐induced renal and hepatic toxicities: Role of apoptosis‐induced tissue proliferation Pubmed: 32045101 |
| life sciences | Nifuroxazide attenuates experimentally-induced hepatic encephalopathy and the associated hyperammonemia and cJNk/caspase-8/TRAIL activation in rats Pubmed: 32259601 |
| Odontology | Effects of different pulp-capping materials on cell death signaling pathways of lipoteichoic acid-stimulated human dental pulp stem cells Pubmed: 33206337 |
| Int Immunopharmacol | Cardio-protective impact of gabapentin against doxorubicin-induced myocardial toxicity in rats; emphasis on modulation of inflammatory-apoptotic signaling Pubmed: 33199237 |
| ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY | Chemo-preventive effect of crocin against experimentally-induced hepatocarcinogenesis via regulation of apoptotic and Nrf2 signaling pathways Pubmed: 32942000 |
| Environ Sci Pollut Res Int | Potentiation of the apoptotic signaling pathway in both the striatum and hippocampus and neurobehavioral impairment in rats exposed chronically to a low− dose of … Pubmed: 32915453 |
| J Biochem Mol Toxicol | Tranilast abrogates cisplatin©\induced testicular and epididymal injuries: An insight into its modulatory impact on apoptosis/proliferation 34047436 |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| RPA853Hu02 | Recombinant Caspase 8 (CASP8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA853Hu03 | Recombinant Caspase 8 (CASP8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA853Hu01 | Recombinant Caspase 8 (CASP8) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA853Hu02 | Polyclonal Antibody to Caspase 8 (CASP8) | WB; IHC; ICC; IP. |
| PAA853Hu01 | Polyclonal Antibody to Caspase 8 (CASP8) | WB,IHC,ICC/IF |
| PAA853Hu03 | Polyclonal Antibody to Caspase 8 (CASP8) | WB,IHC,ICC/IF |
| FAA853Hu01 | Anti-Caspase 8 (CASP8) Polyclonal Antibody | Flow cytometry. |
| LAA853Hu81 | FITC-Linked Polyclonal Antibody to Caspase 8 (CASP8) | WB; IHC; ICC; IF. |
| LAA853Hu71 | Biotin-Linked Polyclonal Antibody to Caspase 8 (CASP8) | WB; IHC; ICC. |
| MAA853Hu21 | Monoclonal Antibody to Caspase 8 (CASP8) | WB; IHC; ICC; IP. |
| MAA853Hu23 | Monoclonal Antibody to Caspase 8 (CASP8) | WB; IHC; ICC; IP. |
| MAA853Hu25 | Monoclonal Antibody to Caspase 8 (CASP8) | WB; IHC; ICC; IP. |
| MAA853Hu24 | Monoclonal Antibody to Caspase 8 (CASP8) | WB; IHC; ICC; IP. |
| MAA853Hu29 | Monoclonal Antibody to Caspase 8 (CASP8) | WB |
| MAA853Hu27 | Monoclonal Antibody to Caspase 8 (CASP8) | WB; IHC; ICC; IP. |
| MAA853Hu22 | Monoclonal Antibody to Caspase 8 (CASP8) | WB; IHC; ICC; IP. |
| SEA853Hu | ELISA Kit for Caspase 8 (CASP8) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA853Hu | Magnetic Luminex Assay Kit for Caspase 8 (CASP8) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
| KSA853Hu01 | ELISA Kit DIY Materials for Caspase 8 (CASP8) | Main materials for "Do It (ELISA Kit) Yourself". |
