Cloud-clone
SKU:RPB479Mu01
Recombinant Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)
Recombinant Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)
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Prokaryotic expression
Product No.
RPB479Mu01
Organism Species
Mus musculus (Mouse).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Cell membrane; Secreted, Single-pass type I membrane protein. extracellular spa
Predicted Molecular Mass
18.9kDa
Accurate Molecular Mass
20kDa(Analysis of differences refer to the manual)
Residues & Tags
Ser25~Thr160 (Accession # Q06186) with
Buffer Formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Traits
Freeze-dried powder
Purity
> 95%
Isoelectric Point
9.6
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in PBS or others.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Neuropathology | Astrocyte ERK phosphorylation precedes K+-induced swelling but follows hypotonicity-induced swelling. PubMed: 21118399 |
| Toxicological Sciences | Cypermethrin Induces Astrocyte Apoptosis by the Disruption of the Autocrine/Paracrine Mode of Epidermal Growth Factor Receptor Signaling Pubmed: source |
| PAIN RESEARCH | 軽度炎症性膀胱痛マウスモデルの構築とNGFの関与 Jstage:Source |
| European Journal of Pain | A novel method for assessing bladder-related pain reveals the involvement of nerve growth factor in painassociated with cyclophosphamide-induced chronic cystitis in mice. Pubmed:25820250 |
| Kinki daigaku | 2 型糖尿病モデルラットにおける糖尿病性腎症の進行とHB-EGF の関連性 17844 |
| laboratory investigation | Heparin-binding epidermal growth factor contributes to COPD disease severity by modulating airway fibrosis and pulmonary epithelial–mesenchymal transition Pubmed:29581578 |
| International Journal of Biological Sciences | CD9 regulates keratinocyte migration by negatively modulating the sheddase activity of ADAM17 |
| Redox Biology | Tumoral NOX4 recruits M2 tumor-associated macrophages via ROS/PI3K signaling-dependent various cytokine production to promote NSCLC growth Pubmed: 30769285 |
| JOURNAL OF CELLULAR AND MOLECULAR MEDICINE | Polarization of ADAM17‐driven EGFR signalling in electric field‐guided collective migration of epidermal sheets Pubmed: 33164313 |
| 象牙芽細胞の枯渇は象牙芽細胞分化と象牙質形成を誘導する |
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