Cloud-clone
SKU:RPB866Ra01
Recombinant Neuregulin 1 (NRG1)
Recombinant Neuregulin 1 (NRG1)
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Prokaryotic expression
Product No.
RPB866Ra01
Organism Species
Rattus norvegicus (Rat).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Membrane, Secreted
Predicted Molecular Mass
15.7kDa
Accurate Molecular Mass
20/18kDa(Analysis of differences refer to the manual)
Residues & Tags
Thr264~Gly393 with N-terminal His Tag
Buffer Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Traits
Freeze-dried powder
Purity
> 95%
Isoelectric Point
9.3
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Neuroscience Letter | Therapeutic effect of co-transplantation of neuregulin 1-transfected-Schwann cells and bone marrow stromal cells on spinal cord hemisection syndrom Cyagen: source |
| PLoS One. | ADAM17 Silencing in Mouse Colon Carcinoma Cells: The Effect on Tumoricidal Cytokines and Angiogenesis PubMed: PMC3519469 |
| The Journal of Clinical Investigation | Cerebrospinal fluid–based kinetic biomarkers of axonal transport in monitoring neurodegeneration PubMed: PMC3428100 |
| Physiol Behav | Dysregulation of Neuregulin-1/ErbB signaling in the prefrontal cortex and hippocampus of rats exposed to chronic unpredictable mild stress PubMed: 26626816 |
| J Toxicol Sci. | Effects of prolonged antipsychotic administration on neureCavia (Guinea pig )lin-1/ErbB signaling in rat prefrontal cortex and myocardium: implications for the therapeutic action and cardiac adverse effect. Pubmed:26961615 |
| journal of cellular and molecular medicine | Qiliqiangxin protects against anoxic injury in cardiac microvascular endothelial cells via NRG-1/ErbB-PI3K/Akt/mTOR pathway. pubmed:28271613 |
| Transl Psychiatry. | Ablation of neuropsin-neuregulin 1 signaling imbalances ErbB4 inhibitory networks and disrupts hippocampal gamma oscillation. pubmed:28267150 |
| Human Molecular Genetics | A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas Pubmed: 30335132 |
| Aging (Albany NY) | Jinmaitong ameliorates diabetic peripheral neuropathy in streptozotocin-induced diabetic rats by modulating gut microbiota and neuregulin Pubmed: 32920546 |
| Catalog No. | Related products for research use of Rattus norvegicus (Rat) Organism species | Applications (RESEARCH USE ONLY!) |
| RPB866Ra01 | Recombinant Neuregulin 1 (NRG1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB866Ra02 | Recombinant Neuregulin 1 (NRG1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB866Ra03 | Recombinant Neuregulin 1 (NRG1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB866Ra04 | Recombinant Neuregulin 1 (NRG1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB866Ra02 | Polyclonal Antibody to Neuregulin 1 (NRG1) | WB; IHC; ICC; IP. |
| PAB866Ra03 | Polyclonal Antibody to Neuregulin 1 (NRG1) | WB; IHC; ICC; IP. |
| PAB866Ra01 | Polyclonal Antibody to Neuregulin 1 (NRG1) | WB; IHC; ICC; IP. |
| PAB866Ra04 | Polyclonal Antibody to Neuregulin 1 (NRG1) | WB; IHC; ICC; IP. |
| LAB866Ra71 | Biotin-Linked Polyclonal Antibody to Neuregulin 1 (NRG1) | WB; IHC; ICC. |
| SEB866Ra | ELISA Kit for Neuregulin 1 (NRG1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| WEB866Ra | Wide-range ELISA Kit for Neuregulin 1 (NRG1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB866Ra | Magnetic Luminex Assay Kit for Neuregulin 1 (NRG1) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
