Cloud-clone
SKU:RPB969Ra01
Recombinant Complement Component 5 (C5)
Recombinant Complement Component 5 (C5)
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Prokaryotic expression
Product No.
RPB969Ra01
Organism Species
Rattus norvegicus (Rat).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Secreted
Predicted Molecular Mass
20.3kDa
Accurate Molecular Mass
20kDa(Analysis of differences refer to the manual)
Residues & Tags
Cys1541~Ala1688 with N-terminal His Tag
Buffer Formulation
PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Traits
Freeze-dried powder
Purity
> 95%
Isoelectric Point
5.9
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Journal of Clinical Immunology | Complement activation contributes to the injury and outcome of kidney in human anti-glomerular basement membrane disease. PubMed: 22941511 |
| Journal of Neuroimmunology | Acute and prolonged complement activation in the central nervous system during herpes simplex encephalitis Pubmed:27235358 |
| Cancer Letters | Complement C5a/C5aR pathway potentiates the pathogenesis Q5 of gastric cancer by down-regulating p21 expression pubmed:29031586 |
| Proteomics Clinical Applications | iTRAQ‐Based Proteomic Analysis Reveals Protein Profile in Plasma from Children with Autism Pubmed:29274201 |
| American journal of physiology. Endocrinology and metabolism | Impaired insulin signaling in the B10.D2-Hc H2 H2-T18/oSnJ mouse model of complement factor 5 (C5) deficiency Pubmed: 31084499 |
| Proteomics Clinical Applications | Comparative proteomics analysis of serum proteins in gestational diabetes during early and middle stages of pregnancy Pubmed: 31162828 |
| Aging | C5aR deficiency attenuates the breast cancer development via the p38/p21 axis Pubmed: 32669478 |
| Catalog No. | Related products for research use of Rattus norvegicus (Rat) Organism species | Applications (RESEARCH USE ONLY!) |
| RPB969Ra01 | Recombinant Complement Component 5 (C5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB969Ra01 | Polyclonal Antibody to Complement Component 5 (C5) | WB; IHC; ICC; IP. |
| MAB969Ra21 | Monoclonal Antibody to Complement Component 5 (C5) | WB; IHC; ICC; IP. |
| SEB969Ra | ELISA Kit for Complement Component 5 (C5) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB969Ra | Magnetic Luminex Assay Kit for Complement Component 5 (C5) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
