Cloud-clone
SKU:RPC580Hu01
Recombinant Lysyl Oxidase (LOX)
Recombinant Lysyl Oxidase (LOX)
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Prokaryotic expression
Product No.
RPC580Hu01
Organism Species
Homo sapiens (Human).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Extracellular matrix
Predicted Molecular Mass
53.7kDa
Accurate Molecular Mass
53kDa(Analysis of differences refer to the manual)
Residues & Tags
Pro213~Tyr417 with N-terminal His and GST Tag
Buffer Formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Traits
Freeze-dried powder
Purity
> 90%
Isoelectric Point
6.2
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| American Journal of Hematology | The expression of lysyl-oxidase gene family members in myeloproliferative neoplasms. PubMed: 23494965 |
| Current Eye Research | High Glucose Induced Differential Expression of Lysyl Oxidase and Its Isoform in ARPE-19 Cells Pubmed: 22966818 |
| European Journal of Surgical Oncology | Evaluation of serum lysyl oxidase as a blood test for colorectal cancer Pubmed: 24246612 |
| Vaccine | Copia autorizada por CDR Ingentaconnect: Source |
| Arthritis & Rheumatology | Lysyl oxidase is a potential biomarker of fibrosis in systemic sclerosis Pubmed: 24574233 |
| Eur J Surg Oncol.? | Evaluation of serum lysyl oxidase as a blood test for colorectal cancer Pubmed:Pmc4237001 |
| BMC Cancer. | Ionizing radiation induces tumor cell lysyl oxidase secretion Pubmed:Pmc4223762 |
| DNA Cell Biol. | Lysyl Oxidase Genetic Variants Affect Gene Expression in Cervical Cancer Pubmed:24945327 |
| scandinavian journal of immunology | Increased Serum Levels of the IL-33 Neutralizing sST2 in Limited Cutaneous Systemic Sclerosis PubMed: 26095613 |
| Curr Eye Res | Correlation of Aqueous Humor Lysyl Oxidase Activity with TGF-ß Levels and LOXL1 Genotype in Pseudoexfoliation Pubmed:27116380 |
| journal of bone and mineral metabolism | LOX Fails to Substitute for RANKL in Osteoclastogenesis. pubmed:27606829 |
| 38 | Blocking Surgically Induced Lysyl Oxidase Activity Reduces the Risk of Lung Metastases. pubmed:28445728 |
| Molecular Medicine Reports | Lysyl oxidase is involved in synovial hyperplasia and angiogenesis in rats with collagen‑induced arthritis pubmed:28901438 |
| Revista Española de Cardiología (English Edition) | A Global Assessment of Circulating Prolysyl Oxidase in Nonischemic Patients With Garden-variety Heart Failure With Preserved Ejection Fraction Pubmed:29807761 |
| Molecular Medicine Reports | Lysyl oxidase inhibition via β-aminoproprionitrile hampers human umbilical vein endothelial cell angiogenesis and migration in vitro Pubmed:29393489 |
| Thyroid | Lysyl Oxidase is a key player in BRAF/MAPK pathway-driven thyroid cancer aggressiveness Pubmed: 30398411 |
| Am J Physiol Lung Cell Mol Physiol | Lysyl Oxidase Directly Contributes to Extracellular Matrix Production and Fibrosis in Systemic Sclerosis. Pubmed: 33026236 |
| J Am Heart Assoc | Collagen Cross©\Linking Is Associated With Cardiac Remodeling in Hypertrophic Obstructive Cardiomyopathy 33356379 |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| APC580Hu01 | Active Lysyl Oxidase (LOX) | Cell culture; Activity Assays. |
| RPC580Hu01 | Recombinant Lysyl Oxidase (LOX) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPC580Hu02 | Recombinant Lysyl Oxidase (LOX) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPC580Hu61 | Eukaryotic Lysyl Oxidase (LOX) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAC580Hu02 | Polyclonal Antibody to Lysyl Oxidase (LOX) | WB; IHC; ICC; IP. |
| PAC580Hu01 | Polyclonal Antibody to Lysyl Oxidase (LOX) | WB; IHC; ICC; IP. |
| LAC580Hu81 | FITC-Linked Polyclonal Antibody to Lysyl Oxidase (LOX) | WB; IHC; ICC; IF. |
| LAC580Hu71 | Biotin-Linked Polyclonal Antibody to Lysyl Oxidase (LOX) | WB; IHC; ICC. |
| MAC580Hu22 | Monoclonal Antibody to Lysyl Oxidase (LOX) | WB; IHC; ICC; IP. |
| SEC580Hu | ELISA Kit for Lysyl Oxidase (LOX) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| WEC580Hu | Wide-range ELISA Kit for Lysyl Oxidase (LOX) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMC580Hu | Magnetic Luminex Assay Kit for Lysyl Oxidase (LOX) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
| KSC580Hu01 | ELISA Kit DIY Materials for Lysyl Oxidase (LOX) | Main materials for "Do It(ELISA Kit) Yourself" |
