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SKU:RPC615Hu01
Recombinant Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
Recombinant Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
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Prokaryotic expression
Product No.
RPC615Hu01
Organism Species
Homo sapiens (Human).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Membrane, Nucleus, Mitochondrion, Cytoplasm
Predicted Molecular Mass
38.3kDa
Accurate Molecular Mass
38kDa(Analysis of differences refer to the manual)
Residues & Tags
Arg6~Ile328 with N-terminal His Tag
Buffer Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Traits
Freeze-dried powder
Purity
> 90%
Isoelectric Point
5.2
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Cancers | Rationale for a Combination Therapy Consisting of MCL1-and MEK-Inhibitors in Acute Myeloid Leukemia Pubmed: 31718075 |
| ACTA NEUROPATHOLOGICA COMMUNICATIONS | Restoration of miR-193a expression is tumor-suppressive in MYC amplified Group 3 medulloblastoma Pubmed: 32410663 |
| Cancers (Basel) | BMI1-Inhibitor PTC596 in Combination with MCL1 Inhibitor S63845 or MEK Inhibitor Trametinib in the Treatment of Acute Leukemia. Cancers 2021, 13, 581 33540760 |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| RPC615Hu01 | Recombinant Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAC615Hu01 | Polyclonal Antibody to Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) | WB; IHC; ICC; IP. |
| FAC615Hu01 | Anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) Polyclonal Antibody | Flow cytometry. |
| MAC615Hu22 | Monoclonal Antibody to Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) | WB; IHC; ICC; IP. |
| SEC615Hu | ELISA Kit for Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMC615Hu | Magnetic Luminex Assay Kit for Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
