Cloud-clone
SKU:RPD686Ra01
Recombinant 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR)
Recombinant 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR)
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Prokaryotic expression
Product No.
RPD686Ra01
Organism Species
Rattus norvegicus (Rat).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Endoplasmic reticulum lumen
Predicted Molecular Mass
30.0kDa
Accurate Molecular Mass
30kDa(Analysis of differences refer to the manual)
Residues & Tags
Ala638~Ala887 with N-terminal His Tag
Buffer Formulation
100mMNaHCO3, 500mMNaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Traits
Freeze-dried powder
Purity
> 97%
Isoelectric Point
8.4
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 100mM NaHCO3, 500mM NaCl (pH8.3) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Neuroscience | 27-Hydroxycholesterol contributes to disruptive effects on learning and memory by modulating cholesterol metabolism in the rat brain PubMed: 25987203 |
| Neurotoxicology. | 27-Hydroxycholesterol regulates cholesterol synthesis and transport in C6 glioma cells. pubmed:28167099 |
| archives of medical research | Transthyretin Regulated by linc00657/miR-205-5p Promoted Cholesterol Metabolism by Inducing SREBP2-HMGCR and Inhibiting LXRα-CYP7A1 Pubmed: 32241558 |
| Catalog No. | Related products for research use of Rattus norvegicus (Rat) Organism species | Applications (RESEARCH USE ONLY!) |
| RPD686Ra01 | Recombinant 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAD686Ra01 | Polyclonal Antibody to 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR) | WB; IHC; ICC; IP. |
| MAD686Ra21 | Monoclonal Antibody to 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR) | WB; IHC; ICC; IP. |
| SED686Ra | ELISA Kit for 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMD686Ra | Magnetic Luminex Assay Kit for 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase (HMGCR) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
