Cloud-clone
SKU:RPE748Hu01
Recombinant Karyopherin Alpha 2 (KPNa2)
Recombinant Karyopherin Alpha 2 (KPNa2)
Couldn't load pickup availability
Prokaryotic expression
Product No.
RPE748Hu01
Organism Species
Homo sapiens (Human).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Nucleus, Cytoplasm
Predicted Molecular Mass
31.0kDa
Accurate Molecular Mass
27kDa(Analysis of differences refer to the manual)
Residues & Tags
Ala157~Gln412 with N-terminal His Tag
Buffer Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Traits
Freeze-dried powder
Purity
> 97%
Isoelectric Point
5.0
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Oncol Rep.? | KPNA2 is a promising biomarker candidate for esophageal squamous cell carcinoma and correlates with cell proliferation Pubmed:25109899 |
| Tumor Biology | KPNA2 is a potential diagnostic serum biomarker for epithelial ovarian cancer and correlates with poor prognosis pubmed:28651492 |
| Head & Neck | Association of overexpressed karyopherin alpha 2 with poor survival and its contribution to interleukin‐1β‐induced matrix metalloproteinase expression in oral cancer Pubmed:29542209 |
| International Journal of Cancer | Nuclear transport proteins are secreted by cancer cells and identified as potential novel cancer biomarkers 34591985 |
