Cloud-clone
SKU:RPB477Mu01
Recombinant Matrix Gla Protein (MGP)
Recombinant Matrix Gla Protein (MGP)
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Prokaryotic expression
Product No.
RPB477Mu01
Organism Species
Mus musculus (Mouse).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Secreted
Predicted Molecular Mass
16.2kDa
Accurate Molecular Mass
20kDa(Analysis of differences refer to the manual)
Residues & Tags
Tyr20~Tyr104 with N-terminal His Tag
Buffer Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Traits
Freeze-dried powder
Purity
> 97%
Isoelectric Point
8.5
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Nephrology Dialysis Transplantation | Magnesium prevents phosphate-induced calcification in human aortic vascular smooth muscle cells PubMed: PMC3611891 |
| Maturitas. | Bone metabolism regulators and arterial stiffness in postmenopausal women Pubmed: 23916080 |
| The Egyptian Rheumatologist | Osteoprotegerin (OPG) and Matrix Gla protein (MGP) in rheumatoid arthritis patients: Relation to disease activity ScienceDirect: S1110116414000076 |
| Toxicology Reports | Canola and hydrogenated soybean oils accelerate ectopic bone formation induced by implantation of bone morphogenetic protein in mice Researchgate:Source |
| Lipids in Health and Disease | Markers of increased cardiovascular risk in patients with chronic kidney disease Biomedcentral:Source |
| Human & Veterinary Medicine | The behavior of circulating matrix Gla protein, matrix metalloproteinase-9 and nitrotyrosine in patients with varicose veins Hvm:Source |
| Pol Arch Med Wewn | Effect of Vitamin K2 on progression of atherosclerosis and vascular calcification in nondialyzed patients with chronic kidney disease stages 3-5 PubMed: 26176325 |
| Lipids Health Dis. | Markers of increased atherosclerotic risk in patients with chronic kidney disease: a preliminary study pmc:PMC4739105 |
| Kidney Blood Press Res. | Plasma Desphospho-Uncarboxylated Matrix Gla Protein as a Marker of Kidney Damage and Cardiovascular Risk in Advanced Stage of Chronic Kidney Disease Pubmed:27100101 |
| Archives of Oral Biology | Matrix-Gla Protein rs4236 [A/G] gene polymorphism and serum and GCF levels of MGP in patients with subgingival dental calculus pubmed:27348051 |
| Cell Death & Disease | Mesenchymal stromal cells-derived matrix Gla protein contribute to the alleviation of experimental colitis Pubmed:29880866 |
| Urology | High concentration of calcium promotes mineralization in NRK52E cells via inhibiting the expression of matrix Gla protein Pubmed:29935264 |
| Clinica Chimica Acta | Serum total matrix Gla protein: Reference interval in healthy adults and variations in patients with vascular and osteoarticular diseases Pubmed: 30597137 |
| Biological Trace Element Research | Altered Mineral Metabolism and Disequilibrium Between Calcification Promoters and Inhibitors in Chronic Hemodialysis Patients Pubmed: 30847765 |
| Renal Failure | Relationship of matrix Gla protein and vitamin K with vascular calcification in hemodialysis patients Pubmed: 31538831 |
| Heliyon | Matrix Gla protein maintains normal and malignant hematopoietic progenitor cells by interacting with bone morphogenetic protein-4 Pubmed: 32322728 |
| Catalog No. | Related products for research use of Mus musculus (Mouse) Organism species | Applications (RESEARCH USE ONLY!) |
| RPB477Mu02 | Recombinant Matrix Gla Protein (MGP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB477Mu01 | Recombinant Matrix Gla Protein (MGP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB477Mu01 | Polyclonal Antibody to Matrix Gla Protein (MGP) | WB; IHC; ICC; IP. |
| PAB477Mu02 | Polyclonal Antibody to Matrix Gla Protein (MGP) | WB; IHC; ICC; IP. |
| LAB477Mu71 | Biotin-Linked Polyclonal Antibody to Matrix Gla Protein (MGP) | WB; IHC; ICC. |
| SEB477Mu | ELISA Kit for Matrix Gla Protein (MGP) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB477Mu | Magnetic Luminex Assay Kit for Matrix Gla Protein (MGP) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
