Cloud-clone
SKU:RPE787Gu01
Recombinant Annexin A1 (ANXA1)
Recombinant Annexin A1 (ANXA1)
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Prokaryotic expression
Product No.
RPE787Gu01
Organism Species
Cavia (Guinea pig ).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Membrane, Secreted, Cytoplasm
Predicted Molecular Mass
19.7kDa
Accurate Molecular Mass
20kDa(Analysis of differences refer to the manual)
Residues & Tags
Ile224~Glu336 with Two N-terminal Tags, His-tag and SUMO-tag
Buffer Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Traits
Freeze-dried powder
Purity
> 90%
Isoelectric Point
6.8
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Plos one | Dysregulation of Anti-Inflammatory Annexin A1 Expression in Progressive Crohns Disease PubMed: PMC3794972 |
| African Journals Online | Modulatory Effect of Phytoestrogens and Curcumin on Induction of Annexin 1 in Human Peripheral Blood Mononuclear Cells and their Inhibitory Effect on Secretory Phospholipase A2 Ajol: Source |
| Antimicrobial Agents and Chemotherapy | Host Biomarkers of Invasive Pulmonary Aspergillosis to Monitor Therapeutic Response Asm: Source |
| J Proteomics | Characterization of secretomes from a human blood brain barrier endothelial cells in-vitro model after ischemia by stable isotope labeling with aminoacids in cell culture (SILAC) PubMed: 26718731 |
| Diabetes | Annexin A1 Is a Key Modulator of Mesenchymal Stromal Cell–Mediated Improvements in Islet Function PubMed: 26470781 |
| PLoS One | Annexin A1 Is Increased in the Plasma of Preeclamptic Women PubMed: 26398190 |
| 中国现代医学杂志 China Journal of Modern Medicine | 膜联蛋白A1 和CA19-9 在胆管癌中的表达及其临床意义 article:8686 |
| arteriosclerosis thrombosis and vascular biology | Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice-Brief Report. pubmed:28062503 |
| Clinical Science | Mesenchymal stromal cells improve human islet function through released products and extracellular matrix. pubmed:29101297 |
| Biomedicine & Pharmacotherapy | Proresolving protein Annexin A1: The role in type 2 diabetes mellitus and obesity Pubmed:29677533 |
| International Journal of Chronic Obstructive Pulmonary Disease | Annexin A1 is elevated in patients with COPD and affects lung fibroblast function Pubmed:29440885 |
| Medical Mycology | Applying host disease status biomarkers to therapeutic response monitoring in invasive aspergillosis patients Pubmed:29370415 |
| DEVELOPMENTAL NEUROPSYCHOLOGY | EFFECTS OF MULTICOMPONENT EXERCISE ON PROGRESSION OF BRAIN ATROPHY AND COGNITION IN AMNESTIC MILD COGNITIVE IMPAIRMENT … pdf:3395 |
| Multiple sclerosis and related disorders | Resolution of inflammation in neuromyelitis optica spectrum disorders Pubmed: 30300851 |
| Acta Pharmaceutica | Effects of annexin A1 on apoptosis and cell cycle arrest in human leukemic cell lines |
| npj Science of Food | Annexin A1 accounts for an anti-inflammatory binding target of sesamin metabolites Pubmed: 32133417 |
| FASEB JOURNAL | ANXA1 directs Schwann cells proliferation and migration to accelerate nerve regeneration through the FPR2/AMPK pathway Pubmed: 32908567 |
| Rev Soc Bras Med Trop | Expression of annexin-A1 in blood and tissue leukocytes of leprosy patients 33263684 |
| science advances | Annexin-A1 SUMOylation regulates microglial polarization after cerebral ischemia by modulating IKK¦Á stability via selective autophagy 33523920 |
| Catalog No. | Related products for research use of Cavia (Guinea pig ) Organism species | Applications (RESEARCH USE ONLY!) |
| RPE787Gu01 | Recombinant Annexin A1 (ANXA1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAE787Gu01 | Polyclonal Antibody to Annexin A1 (ANXA1) | WB; IHC; ICC; IP. |
| LAE787Gu71 | Biotin-Linked Polyclonal Antibody to Annexin A1 (ANXA1) | WB; IHC; ICC. |
| MAE787Gu21 | Monoclonal Antibody to Annexin A1 (ANXA1) | WB; IHC; ICC; IP. |
