Cloud-clone
SKU:RPB280Hu02
Recombinant Cathepsin D (CTSD)
Recombinant Cathepsin D (CTSD)
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Prokaryotic expression
Product No.
RPB280Hu02
Organism Species
Homo sapiens (Human).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Secreted
Predicted Molecular Mass
27.5kDa
Accurate Molecular Mass
27kDa(Analysis of differences refer to the manual)
Residues & Tags
Leu169~Glu408 with N-terminal His Tag
Buffer Formulation
PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Traits
Freeze-dried powder
Purity
> 97%
Isoelectric Point
5.97
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Molecular Immunology | Cathepsin D is released after severe tissue trauma in vivo and is capable of generating C5a in vitro ScienceDirect: S0161589011008297 |
| 21 | Plasma Cathepsin D Levels: A Novel Tool to Predict Pediatric Hepatic Inflammation PubMed: 25732418 |
| Scientific Reportes | Plasma cathepsin D correlates with histological classifications of fatty liver disease in adults and responds to intervention pubmed:27922112 |
| Biomedicine & pharmacotherapy | Berberine ameliorates intrahippocampal kainate-induced status epilepticus and consequent epileptogenic process in the rat: Underlying mechanisms pubmed:28061403 |
| JGH OPEN | Limited applicability of cathepsin D for the diagnosis and monitoring of non‐alcoholic steatohepatitis |
| Diabetologia | Plasma cathepsin D activity is negatively associated with hepatic insulin sensitivity in overweight and obese humans Pubmed: 31690989 |
| Antioxidants | Iron and Advanced Glycation End Products: Emerging Role of Iron in Androgen Deficiency in Obesity Pubmed: 32235809 |
| Peptides | LVV-hemorphin-7 (LVV-H7) plays a role in antinociception in a rat model of alcohol-induced pain disorders 33253777 |
| Cells | Identification of Cathepsin D as a Plasma Biomarker for Alzheimer's Disease 33445607 |
| J Chem Neuroanat | Analysis of silymarin-modulating effects against acrylamide-induced cerebellar damage in male rats: Biochemical and pathological markers 33965515 |
| Front Cell Infect Microbiol | PGRS Domain of Rv0297 of Mycobacterium tuberculosis Is Involved in Modulation of Macrophage Functions to Favor Bacterial Persistence 33042856 |
| Nutr Metab Cardiovasc Dis | Serum CathepsinD in pregnancy: relation with metabolic and inflammatory markers and effects of fish oils and probiotics Pubmed:35304048 |
| Biosensors | A Comparison of Various Chips Used for the Manufacture of Biosensors Applied in Non-Fluidic Array SPRi, Based on the Example of Determination of Cathepsin D Pubmed:35049649 |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| APB280Hu61 | Active Cathepsin D (CTSD) | Cell culture; Activity Assays. |
| EPB280Hu61 | Eukaryotic Cathepsin D (CTSD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB280Hu01 | Recombinant Cathepsin D (CTSD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| EPB280Hu62 | Eukaryotic Cathepsin D (CTSD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB280Hu02 | Recombinant Cathepsin D (CTSD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB280Hu03 | Recombinant Cathepsin D (CTSD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB280Hu04 | Recombinant Cathepsin D (CTSD) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB280Hu02 | Polyclonal Antibody to Cathepsin D (CTSD) | WB; IHC; ICC; IP. |
| PAB280Hu01 | Polyclonal Antibody to Cathepsin D (CTSD) | WB; IHC; ICC; IP. |
| LAB280Hu71 | Biotin-Linked Polyclonal Antibody to Cathepsin D (CTSD) | WB; IHC; ICC. |
| MAB280Hu21 | Monoclonal Antibody to Cathepsin D (CTSD) | WB; IHC; ICC; IP. |
| MAB280Hu26 | Monoclonal Antibody to Cathepsin D (CTSD) | WB; IHC; ICC; IP. |
| MAB280Hu22 | Monoclonal Antibody to Cathepsin D (CTSD) | WB; IHC; ICC; IP. |
| SEB280Hu | ELISA Kit for Cathepsin D (CTSD) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| HEB280Hu | High Sensitive ELISA Kit for Cathepsin D (CTSD) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB280Hu | Magnetic Luminex Assay Kit for Cathepsin D (CTSD) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
