Cloud-clone
SKU:RPE189Ra01
Recombinant Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)
Recombinant Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)
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Product No.
RPE189Ra01
Organism Species
Rattus norvegicus (Rat).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Secreted, Lysosome, Cytoplasm, Golgi apparatus, Endoplasmic reticulum lumen, Endosome
Predicted Molecular Mass
58.1kDa
Accurate Molecular Mass
58kDa(Analysis of differences refer to the manual)
Residues & Tags
Trp164~Phe428 with N-terminal His and GST Tag
Buffer Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Traits
Freeze-dried powder
Purity
> 90%
Isoelectric Point
5.9
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Biological Trace Element Research | Synergistic Cardioprotective Effects of Combined Chromium Picolinate and Atorvastatin Treatment in Triton X-100-Induced Hyperlipidemia in Rats: Impact on Some Biochemical Markers pubmed:28409410 |
| BASIC RESEARCH IN CARDIOLOGY | Autocrine effects of PCSK9 on cardiomyocytes Pubmed: 33169229 |
| J Transl Med | Multi-omic signatures of atherogenic dyslipidaemia: pre-clinical target identification and validation in humans 33407555 |
| Metabolism | MiR-337-3p lowers serum LDL-C level through targeting PCSK9 in hyperlipidemic mice 33775647 |
| Eur Rev Med Pharmacol Sci | Association of serum proprotein convertase Subtilisin/Kexin Type 9 (PCSK9) level with thyroid function disorders 34533801 |
| Clin Exp Hypertens | Proprotein convertase subtilisin/kexin type 9 is associated with atherosclerosis in patients with Behcet's disease Pubmed:35502687 |
| Catalog No. | Related products for research use of Rattus norvegicus (Rat) Organism species | Applications (RESEARCH USE ONLY!) |
| RPE189Ra01 | Recombinant Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAE189Ra01 | Polyclonal Antibody to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) | WB; IHC; ICC; IP. |
| MAE189Ra23 | Monoclonal Antibody to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) | WB; IHC; ICC; IP. |
| MAE189Ra22 | Monoclonal Antibody to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) | WB; IHC; ICC; IP. |
| MAE189Ra21 | Monoclonal Antibody to Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) | WB; IHC |
| SEE189Ra | ELISA Kit for Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LME189Ra | Magnetic Luminex Assay Kit for Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
