Recombinant Angiopoietin Like Protein 8 (ANGPTL8)

Prokaryotic expression

Product No.

RPW803Mu01

Organism Species

Mus musculus (Mouse).

Source

Prokaryotic expression

Host

E.coli

Endotoxin Level

<1.0EU per 1µg (determined by the LAL method)

Subcellular Location

Secreted

Predicted Molecular Mass

24.2kDa

Accurate Molecular Mass

24kDa(Analysis of differences refer to the manual)

Residues & Tags

Val16~Ala198 with N-terminal His Tag

Buffer Formulation

20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Traits

Freeze-dried powder

Purity

> 90%

Isoelectric Point

7.3

Applications

Positive Control; Immunogen; SDS-PAGE; WB.

If bio-activity of the protein is needed, please check active protein.

UOM

10µg 50µg 200µg 1mg 5mg

SEQUENCE

 

 

 

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

 

Magazine	Citations
PLoS One	Increased Maternal and Cord Blood Betatrophin in Gestational Diabetes PubMed: 26115519
Nutrición Hospitalaria	Serum betatrophin level increased in subjects with metabolic syndrome: a case-control study wp-content:10563
Mediators of Inflammation	Serum betatrophin level increased in subjects with nonalcoholic fatty liver disease files:ijcem0020951.pdf
PLoS One	Resolving Discrepant Findings on ANGPTL8 in β-Cell Proliferation: A Collaborative Approach to Resolving the Betatrophin Controversy pubmed:27410263
Obesity Research and Clinical Practice	Relationship between serum betatrophin levels and the first-phase of glucose-stimulated insulin secretion pubmed:27554132
打不开网页	Aumento del nivel de betatrofina en suero en sujetos con síndrome metabólico: estudio de casos y controles :
DIABETES & METABOLISM	Levels of betatrophin decrease during pregnancy despite increased insulin resistance, beta-cellfunction and triglyceride levels. pubmed:27555469
	Decreased circulating levels of betatrophin in Chinese women with polycystic ovary syndrome :
International Journal of Endocrinology	Serum concentrations of betatrophin and its association with indirect indices of insulin resistance and beta cell function in women with polycystic ovary … pubmed:28702052
Diabetes Research and Clinical Practice	Angiopoietin-like protein 8: an attractive biomarker for the evaluation of subjects with insulin resistance and related disorders pubmed:28965028
Diabetes/Metabolism Research and Reviews	ANGPTL8 (Betatrophin) Role in Diabetes and Metabolic Diseases pubmed:28722798
Bibliography	The Correlation Between Circulating Betatrophin and Insulin Resistance in General Population: A Meta-Analysis pubmed:28931172
Frontiers in Endocrinology	ANGPTL8: an important regulator in metabolic disorders Pubmed:29719529
Nutrients	ChREBP Reciprocally Regulates Liver and Plasma Triacylglycerol Levels in Different Manners Pubmed: 30405056
Nature Communications	Angptl8 mediates food-driven resetting of hepatic circadian clock in mice Pubmed: 31388006
Journal of Immunology Research	The Impact of Psoriasis and Metabolic Syndrome on the Systemic Inflammation and Oxidative Damage to Nucleic Acids Pubmed: 32537470
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM	Genetic and Metabolic Determinants of Plasma Levels of ANGPTL8 33619548
Medicine	Association of betatrophin amounts with 25-(OH) D levels in patients with gestational diabetes mellitus 33879746
International Journal of Endocrinology	Effect of Ileal Transposition (IT) on Angiopoietin-Like Protein-8 (ANGPTL8) and Pentraxin (PTX3) Plasma Level in Sprague-Dawley Rats Fed High-Fat Diet?¡­ 34035808

Catalog No.	Related products for research use of Mus musculus (Mouse) Organism species	Applications (RESEARCH USE ONLY!)
RPW803Mu01	Recombinant Angiopoietin Like Protein 8 (ANGPTL8)	Positive Control; Immunogen; SDS-PAGE; WB.
RPW803Mu02	Recombinant Angiopoietin Like Protein 8 (ANGPTL8)	Positive Control; Immunogen; SDS-PAGE; WB.
PAW803Mu01	Polyclonal Antibody to Angiopoietin Like Protein 8 (ANGPTL8)	WB; IHC; ICC; IP.
PAW803Mu02	Polyclonal Antibody to Angiopoietin Like Protein 8 (ANGPTL8)	WB; IHC; ICC; IP.
SEW803Mu	ELISA Kit for Angiopoietin Like Protein 8 (ANGPTL8)	Enzyme-linked immunosorbent assay for Antigen Detection.
LMW803Mu	Magnetic Luminex Assay Kit for Angiopoietin Like Protein 8 (ANGPTL8) ,etc.	Magnetic Luminex Assay for Antigen Detection.