Cloud-clone
SKU:RPA792Ra01
Recombinant Topoisomerase II (TOP2)
Recombinant Topoisomerase II (TOP2)
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Prokaryotic expression
Product No.
RPA792Ra01
Organism Species
Rattus norvegicus (Rat).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Nucleus
Predicted Molecular Mass
32.1kDa
Accurate Molecular Mass
40kDa(Analysis of differences refer to the manual)
Residues & Tags
Gly1079~Ser1328 with N-terminal His Tag
Buffer Formulation
PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Traits
Freeze-dried powder
Purity
> 97%
Isoelectric Point
6.1
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Journal of Experimental & Clinical Cancer Research | Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II pubmed:27852319 |
| Bioorganic & Medicinal Chemistry | Synthesis of pharmacologically important naphthoquinones and anticancer activity of 2-benzyllawsone through DNA topoisomerase-II inhibition. pubmed:28094224 |
| European Journal of Medicinal Chemistry | Antiproliferative activity of diarylnaphthylpyrrolidine derivative via dual target inhibition Pubmed: 31884407 |
| Int J Mol Sci | 2-{5-[(Z,2Z)-2-Chloro-3-(4-nitrophenyl)-2-propenylidene]-4-oxo-2-thioxothiazolidin-3-yl}-3-methylbutanoic Acid as a Potential Anti-Breast Cancer Molecule Pubmed:35456915 |
| Catalog No. | Related products for research use of Rattus norvegicus (Rat) Organism species | Applications (RESEARCH USE ONLY!) |
| RPA792Ra01 | Recombinant Topoisomerase II (TOP2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA792Ra01 | Polyclonal Antibody to Topoisomerase II (TOP2) | WB; IHC; ICC; IP. |
| MAA792Ra21 | Monoclonal Antibody to Topoisomerase II (TOP2) | WB; IHC; ICC; IP. |
| SEA792Ra | ELISA Kit for Topoisomerase II (TOP2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA792Ra | Magnetic Luminex Assay Kit for Topoisomerase II (TOP2) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
