Cloud-clone
SKU:RPA684Ra01
Recombinant Mucin 5 Subtype B (MUC5B)
Recombinant Mucin 5 Subtype B (MUC5B)
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Prokaryotic expression
Product No.
RPA684Ra01
Organism Species
Rattus norvegicus (Rat).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Secreted
Predicted Molecular Mass
42.9kDa
Accurate Molecular Mass
44kDa(Analysis of differences refer to the manual)
Residues & Tags
Arg3539~Gly3637 with N-terminal His and GST Tag
Buffer Formulation
PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Traits
Freeze-dried powder
Purity
> 95%
Isoelectric Point
5.6
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| The Journal of Biological Chemistry | The Extracellular Signal-regulated Kinase Mitogen-activated Protein Kinase/Ribosomal S6 Protein Kinase 1 Cascade Phosphorylates cAMP Response Element-binding Protein to Induce MUC5B Gene Expression via D-Prostanoid Receptor Signaling Jcb: 34199 |
| The Journal of Biological Chemistry | The ERK MAPK/RSK1 cascade phosphorylates CREB to induce MUC5B gene expression via DP1 receptor signaling Jcb: 247684 |
| Respiratory Researh | Pyocyanin-induced mucin production is associated with redox modification of FOXA2 PubMed: PMC3765780 |
| Respirology | Secreted mucins and airway bacterial colonization in non-CF bronchiectasis PubMed: 26172851 |
| American Thoracic Society International Conference Abstracts | Mucin Secretion In Asthmatics With Osmotic Airway Hyperresponsiveness doi:10.1164 |
| Ann Am Thorac Soc | Airway Mucin 2 Is Decreased in Patients with Severe Chronic Obstructive Pulmonary Disease with Bacterial Colonization doi:10.1513 |
| Секреторно-экссудативная реакция слизистой носа на воздействие холодного воздуха у больных бронхиальной астмой 10.20538/1682-0363-2017-2-146-158 | |
| Allergy | Th2 cytokines orchestrate the secretion of MUC 5 AC and MUC 5B in IL‐5 positive chronic rhinosinusitis with nasal polyps Pubmed:29802623 |
| European Journal of Pharmacology | Salvianolic acid B improves airway hyperresponsiveness by inhibiting MUC5AC overproduction associated with Erk1/2/P38 signaling Pubmed:29382534 |
| Japan Society of Immunology & Allergology in Otolaryngology | インフルエンザ菌Phosphorylcholine の表出と中耳ムチンMUC5AC 及びMUC5B 産生への影響 10.5648:jjiao.36.7 |
| Journal of Investigative Medicine | The characteristics and clinical significance of mucin levels in bronchoalveolar lavage fluid of patients with interstitial lung disease Pubmed: 30573494 |
| Mucosal Immunology | ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism Pubmed: 31278375 |
| Catalog No. | Related products for research use of Rattus norvegicus (Rat) Organism species | Applications (RESEARCH USE ONLY!) |
| RPA684Ra02 | Recombinant Mucin 5 Subtype B (MUC5B) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA684Ra03 | Recombinant Mucin 5 Subtype B (MUC5B) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA684Ra01 | Recombinant Mucin 5 Subtype B (MUC5B) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA684Ra03 | Polyclonal Antibody to Mucin 5 Subtype B (MUC5B) | WB; IHC; ICC; IP. |
| PAA684Ra02 | Polyclonal Antibody to Mucin 5 Subtype B (MUC5B) | WB; IHC; ICC; IP. |
| PAA684Ra01 | Polyclonal Antibody to Mucin 5 Subtype B (MUC5B) | WB; IHC; ICC; IP. |
| SEA684Ra | ELISA Kit for Mucin 5 Subtype B (MUC5B) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA684Ra | Magnetic Luminex Assay Kit for Mucin 5 Subtype B (MUC5B) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
| KSA684Ra01 | ELISA Kit DIY Materials for Mucin 5 Subtype B (MUC5B) | Main materials for "Do It (ELISA Kit) Yourself" |
