Cloud-clone
SKU:RPA699Hu02
Recombinant Cyclooxygenase-2 (COX 2)
Recombinant Cyclooxygenase-2 (COX 2)
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Prokaryotic expression
Product No.
RPA699Hu02
Organism Species
Homo sapiens (Human).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Membrane
Predicted Molecular Mass
22.5kDa
Accurate Molecular Mass
25kDa(Analysis of differences refer to the manual)
Residues & Tags
Gly418~Asp589 with N-terminal His Tag
Buffer Formulation
PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Traits
Freeze-dried powder
Purity
> 95%
Isoelectric Point
6.4
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Photodermatology, Photoimmunology & Photomedicine | Diallyl sulfide protects against ultraviolet B-induced skin cancers in SKH-1 hairless mouse: analysis of early molecular events in carcinogenesis Wiley: source |
| Skin Cancer - MedlinePlus Health Information | Molecular mechanisms underlying chemopreventive activities of glycyrrhizic acid against UVB-radiation-induced carcinogenesis in SKH-1 hairless mouse epidermis PubMed: 21545294 |
| Evidence-Based Complementary and Alternative Medicine | Curcumin Protects against UVB-Induced Skin Cancers in SKH-1 Hairless Mouse: Analysis of Early Molecular Markers in Carcinogenesis PubMed: 22888366 |
| Integrative Cancer Therapies | Decalepis hamiltonii inhibits tumor progression and metastasis by regulating the inflammatory mediators and nuclear factor κB subunits Pubmed: 24013642 |
| Journal of ethnopharmacology | Multitargeted protective effect of Abacopteris penangiana against carrageenan-induced chronic prostatitis in rats. Pubmed: 24211397 |
| Int J Clin Exp Pathol | Relationship between epidermal growth factor receptor (EGFR) mutation and serum cyclooxygenase-2 Level, and the synergistic effect of celecoxib and gefitinib on EGFR expression in non-small cell lung cancer cells PubMed: 26464643 |
| Int J Clin Exp Pathol | Monitoring of cyclooxygenase-2 levels can predict EGFR mutations and the efficacy of EGFR-TKI in patients with lung adenocarcinoma PubMed: 26191267 |
| Journal of Biomechanics | The shear wave elastic modulus and the increased nuclear factor kappa B(NF-kB/p65) and cyclooxygenase-2 (COX-2) expression in the area of myofascial trigger points activated in a rat model by blunt trauma to the vastus medialis pubmed:29137729 |
| Journal of Global Pharma Technology | Inflammatory Response of Annona Muricata Linn Leaves Extract in Colorectal Cancer Patients NCT02439580 |
| International Journal of Molecular Sciences | High Expression of IL-1RI and EP2 Receptors in the IL-1β/COX-2 Pathway, and a New Alternative to Non-Steroidal Drugs—Osthole in Inhibition COX-2 Pubmed: 30620999 |
| International Immunopharmacology | A novel concept of immunological and allergy interactions in Autism Spectrum Disorders: Molecular, anti-inflammatory effect of osthole Pubmed: 30953868 |
| Reports of Biochemistry & Molecular Biology | Evaluation of Serum Cyclooxygenase, Hepcidin Levels in Acute Renal Injury (AKI) Patients Following Cardiac Catheterization |
| J Ethnopharmacol | Isolation and characterization of anti-inflammatory and anti-proliferative compound, for B-cell Non-Hodgkin lymphoma, from Nyctanthes arbor-tristis Linn. Pubmed:35398498 |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| RPA699Hu02 | Recombinant Cyclooxygenase-2 (COX 2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA699Hu03 | Recombinant Cyclooxygenase-2 (COX 2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA699Hu01 | Recombinant Cyclooxygenase-2 (COX 2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA699Hu01 | Polyclonal Antibody to Cyclooxygenase-2 (COX 2) | WB,IHC |
| PAA699Hu02 | Polyclonal Antibody to Cyclooxygenase-2 (COX 2) | WB; IHC; ICC; IP. |
| MAA699Hu22 | Monoclonal Antibody to Cyclooxygenase-2 (COX 2) | WB; IHC; ICC; IP. |
| SEA699Hu | ELISA Kit for Cyclooxygenase-2 (COX 2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA699Hu | Magnetic Luminex Assay Kit for Cyclooxygenase-2 (COX 2) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
