Cloud-clone
SKU:RPC546Hu01
Recombinant Insulin Receptor Substrate 1 (IRS1)
Recombinant Insulin Receptor Substrate 1 (IRS1)
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Prokaryotic expression
Product No.
RPC546Hu01
Organism Species
Homo sapiens (Human).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Nucleus, Cytoplasm
Predicted Molecular Mass
31.6kDa
Accurate Molecular Mass
32kDa(Analysis of differences refer to the manual)
Residues & Tags
Asp12~Phe264 with N-terminal His Tag
Buffer Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Traits
Freeze-dried powder
Purity
> 95%
Isoelectric Point
8.9
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| МЕДИЦИНСКИЙ ВЕСТНИК СЕВЕРНОГО КАВКАЗА | Сравнительный анализ уровней антител к инсулиновым рецепторам у детей с сахарным диабетом i типа в зависимости от стадии заболевания article:n |
| Eur Neuropsychopharmacol. | Regulation of insulin receptor phosphorylation in the brains of prenatally stressed rats: New insight into the benefits of antidepressant drug treatment. pubmed:28063625 |
| Diabetes | Lack of brain insulin receptor substrate-1 causes growth retardation, with decreased expression of growth hormone-releasing hormone in the hypothalamus. 33980693 |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| RPC546Hu01 | Recombinant Insulin Receptor Substrate 1 (IRS1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAC546Hu01 | Polyclonal Antibody to Insulin Receptor Substrate 1 (IRS1) | WB; IHC; ICC; IP. |
| MAC546Hu21 | Monoclonal Antibody to Insulin Receptor Substrate 1 (IRS1) | WB; IHC; ICC; IP. |
| SEC546Hu | ELISA Kit for Insulin Receptor Substrate 1 (IRS1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMC546Hu | Magnetic Luminex Assay Kit for Insulin Receptor Substrate 1 (IRS1) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
