Recombinant Amyloid Precursor Protein (APP)

Prokaryotic expression

Product No.

RPB020Hu03

Organism Species

Homo sapiens (Human).

Source

Prokaryotic expression

Host

E.coli

Endotoxin Level

<1.0EU per 1µg (determined by the LAL method)

Subcellular Location

Membrane

Predicted Molecular Mass

50kDa

Accurate Molecular Mass

60kDa(Analysis of differences refer to the manual)

Residues & Tags

Thr366~Asn770 with N-terminal His Tag

Buffer Formulation

PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Traits

Freeze-dried powder

Purity

> 90%

Isoelectric Point

5.6

Applications

Positive Control; Immunogen; SDS-PAGE; WB.

If bio-activity of the protein is needed, please check active protein.

UOM

10µg 50µg 200µg 1mg 5mg

SEQUENCE

 

 

 

USAGE

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

 

Magazine	Citations
Neurochemistry International	Bilobalide regulates soluble amyloid precursor protein release via phosphatidyl inositol 3 kinase-dependent pathway ScienceDirect: S0197018611001641
Neuroscience	Substitution of membrane cholesterol with β-sitosterol promotes nonamyloidogenic cleavage of endogenous amyloid precursor protein Pubmed: 23707801
OncoImmunology	PROOF COVER SHEET
台湾农业研究	(台灣農業研究67 (4): 355-364) 香菇柄水萃物改善糖尿病降低阿茲海默氏症罹病風險初探
Neurotoxicology	Involvement of hippocampal agmatine in β1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in mice Pubmed: 32522471
Metab Brain Dis	Probiotics ameliorates LPS induced neuroinflammation injury on Aβ 1–42, APP, γ-β secretase and BDNF levels in maternal gut microbiota and fetal … Pubmed:35312928
Exp Gerontol	The positive impact of 12 weeks of dance and balance training on the circulating amyloid precursor protein and serotonin concentration as well as physical and … Pubmed:35217193

Catalog No.	Related products for research use of Homo sapiens (Human) Organism species	Applications (RESEARCH USE ONLY!)
RPB020Hu02	Recombinant Amyloid Precursor Protein (APP)	Positive Control; Immunogen; SDS-PAGE; WB.
RPB020Hu03	Recombinant Amyloid Precursor Protein (APP)	Positive Control; Immunogen; SDS-PAGE; WB.
RPB020Hu01	Recombinant Amyloid Precursor Protein (APP)	Positive Control; Immunogen; SDS-PAGE; WB.
PAB020Hu01	Polyclonal Antibody to Amyloid Precursor Protein (APP)	WB; IHC; ICC; IP.
PAB020Hu02	Polyclonal Antibody to Amyloid Precursor Protein (APP)	WB; IHC; ICC; IP.
PAB020Hu03	Polyclonal Antibody to Amyloid Precursor Protein (APP)	WB; IHC; ICC; IP.
MAB020Hu22	Monoclonal Antibody to Amyloid Precursor Protein (APP)	WB; IHC; ICC; IP.
MAB020Hu23	Monoclonal Antibody to Amyloid Precursor Protein (APP)	WB; IHC; ICC; IP.
WEB020Hu	Wide-range ELISA Kit for Amyloid Precursor Protein (APP)	Enzyme-linked immunosorbent assay for Antigen Detection.
SEB020Hu	ELISA Kit for Amyloid Precursor Protein (APP)	Enzyme-linked immunosorbent assay for Antigen Detection.
SCB020Hu	CLIA Kit for Amyloid Precursor Protein (APP)	Chemiluminescent immunoassay for Antigen Detection.
LMB020Hu	Magnetic Luminex Assay Kit for Amyloid Precursor Protein (APP) ,etc.	Magnetic Luminex Assay for Antigen Detection.