Cloud-clone
SKU:EPC034Hu61
Eukaryotic Growth Differentiation Factor 15 (GDF15)
Eukaryotic Growth Differentiation Factor 15 (GDF15)
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Eukaryotic expression
Product No.
EPC034Hu61
Organism Species
Homo sapiens (Human).
Source
Eukaryotic expression
Host
293F cell
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Secreted
Predicted Molecular Mass
14.2kDa
Accurate Molecular Mass
14kDa(Analysis of differences refer to the manual)
Residues & Tags
Ala195~Ile308 with N-terminal His Tag
Buffer Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Traits
Freeze-dried powder
Purity
> 97%
Isoelectric Point
6.5
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Clinical cardiology | Growth Differentiation Factor 15 and Coronary Collateral Formation PubMed: 20014173 |
| Personalized Medicine | Elevated levels of GDF-15 is associated with increased angiotensin II in hypertensive patients with Type 2 diabetes pme-2016-0030 |
| LIFE SCIENCES | Rapamycin improves renal injury induced by Iodixanol in diabetic rats by deactivating the mTOR/p70S6K signaling pathway Pubmed: 32798557 |
| Microbiome changes in patients with chronic heart failure with preserved ejection fraction correlate with fibrosis markers: Description of a Russian cohort | |
| SEMINARS IN DIALYSIS | Serum NT©\proBNP levels are associated with cognitive functions in hemodialysis patients 33423325 |
| Taiwanese Journal of Obstetrics & Gynecology | Is GDF-15 level associated with gestational diabetes mellitus and adverse perinatal outcomes? 33678319 |
| J Inflamm Res | Changes in Plasma Growth Differentiation Factor-15 After Laparoscopic Sleeve Gastrectomy in Morbidly Obese Patients: A Prospective Study 33880052 |
| Russian Journal of Cardiology | Predictive value of growth differentiation factor-15 in patients with myocardial infarction |
| Nutrients | High Fat, High Sugar Diet and DJOS Bariatric Surgery Influence Plasma Levels of Fetuin-B, Growth Differentiation Factor-15, and Pentraxin 3 in Diet-Induced Obese … 34684637 |
| Nat Metab | Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation 34675439 |
| Acta Cardiol Sin | Growth Differentiation Factor 15 is Related with Left Ventricular Recovery in Patients with ST-Elevation Myocardial Infarction after Successful Reperfusion by … 34584380 |
| Surgical Endoscopy | The effect of bariatric surgery on the expression of Growth Differentiation Factor-15/Macrophage-Inhibitory Cytokine-1 (GDF-15/MIC-1) in rat Pubmed:35029766 |
| Journal of Clinical Laboratory Analysis | Plasma growth differentiation factor‐15 in patients with “lone” atrial fibrillation Pubmed:35334497 |
