Eukaryotic Lysyl Oxidase (LOX)

Eukaryotic expression

Product No.

EPC580Hu61

Organism Species

Homo sapiens (Human).

Source

Eukaryotic expression

Host

293F cell

Endotoxin Level

<1.0EU per 1µg (determined by the LAL method)

Subcellular Location

Secreted

Predicted Molecular Mass

30.6kDa

Accurate Molecular Mass

33kDa(Analysis of differences refer to the manual)

Residues & Tags

Asp169~Tyr417 with N-terminal His Tag

Buffer Formulation

20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Traits

Freeze-dried powder

Purity

> 90%

Isoelectric Point

6.3

Applications

Positive Control; Immunogen; SDS-PAGE; WB.

If bio-activity of the protein is needed, please check active protein.

UOM

10µg 50µg 200µg 1mg 5mg

SEQUENCE

 

 

 

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

 

Magazine	Citations
American Journal of Hematology	The expression of lysyl-oxidase gene family members in myeloproliferative neoplasms. PubMed: 23494965
Current Eye Research	High Glucose Induced Differential Expression of Lysyl Oxidase and Its Isoform in ARPE-19 Cells Pubmed: 22966818
European Journal of Surgical Oncology	Evaluation of serum lysyl oxidase as a blood test for colorectal cancer Pubmed: 24246612
Vaccine	Copia autorizada por CDR Ingentaconnect: Source
Arthritis & Rheumatology	Lysyl oxidase is a potential biomarker of fibrosis in systemic sclerosis Pubmed: 24574233
Eur J Surg Oncol.?	Evaluation of serum lysyl oxidase as a blood test for colorectal cancer Pubmed:Pmc4237001
BMC Cancer.	Ionizing radiation induces tumor cell lysyl oxidase secretion Pubmed:Pmc4223762
DNA Cell Biol.	Lysyl Oxidase Genetic Variants Affect Gene Expression in Cervical Cancer Pubmed:24945327
scandinavian journal of immunology	Increased Serum Levels of the IL-33 Neutralizing sST2 in Limited Cutaneous Systemic Sclerosis PubMed: 26095613
Curr Eye Res	Correlation of Aqueous Humor Lysyl Oxidase Activity with TGF-ß Levels and LOXL1 Genotype in Pseudoexfoliation Pubmed:27116380
journal of bone and mineral metabolism	LOX Fails to Substitute for RANKL in Osteoclastogenesis. pubmed:27606829
38	Blocking Surgically Induced Lysyl Oxidase Activity Reduces the Risk of Lung Metastases. pubmed:28445728
Molecular Medicine Reports	Lysyl oxidase is involved in synovial hyperplasia and angiogenesis in rats with collagen‑induced arthritis pubmed:28901438
Revista Española de Cardiología (English Edition)	A Global Assessment of Circulating Prolysyl Oxidase in Nonischemic Patients With Garden-variety Heart Failure With Preserved Ejection Fraction Pubmed:29807761
Molecular Medicine Reports	Lysyl oxidase inhibition via β-aminoproprionitrile hampers human umbilical vein endothelial cell angiogenesis and migration in vitro Pubmed:29393489
Thyroid	Lysyl Oxidase is a key player in BRAF/MAPK pathway-driven thyroid cancer aggressiveness Pubmed: 30398411
Am J Physiol Lung Cell Mol Physiol	Lysyl Oxidase Directly Contributes to Extracellular Matrix Production and Fibrosis in Systemic Sclerosis. Pubmed: 33026236
J Am Heart Assoc	Collagen Cross©\Linking Is Associated With Cardiac Remodeling in Hypertrophic Obstructive Cardiomyopathy 33356379

Catalog No.	Related products for research use of Homo sapiens (Human) Organism species	Applications (RESEARCH USE ONLY!)
APC580Hu01	Active Lysyl Oxidase (LOX)	Cell culture; Activity Assays.
RPC580Hu01	Recombinant Lysyl Oxidase (LOX)	Positive Control; Immunogen; SDS-PAGE; WB.
RPC580Hu02	Recombinant Lysyl Oxidase (LOX)	Positive Control; Immunogen; SDS-PAGE; WB.
EPC580Hu61	Eukaryotic Lysyl Oxidase (LOX)	Positive Control; Immunogen; SDS-PAGE; WB.
PAC580Hu02	Polyclonal Antibody to Lysyl Oxidase (LOX)	WB; IHC; ICC; IP.
PAC580Hu01	Polyclonal Antibody to Lysyl Oxidase (LOX)	WB; IHC; ICC; IP.
LAC580Hu81	FITC-Linked Polyclonal Antibody to Lysyl Oxidase (LOX)	WB; IHC; ICC; IF.
LAC580Hu71	Biotin-Linked Polyclonal Antibody to Lysyl Oxidase (LOX)	WB; IHC; ICC.
MAC580Hu22	Monoclonal Antibody to Lysyl Oxidase (LOX)	WB; IHC; ICC; IP.
SEC580Hu	ELISA Kit for Lysyl Oxidase (LOX)	Enzyme-linked immunosorbent assay for Antigen Detection.
WEC580Hu	Wide-range ELISA Kit for Lysyl Oxidase (LOX)	Enzyme-linked immunosorbent assay for Antigen Detection.
LMC580Hu	Magnetic Luminex Assay Kit for Lysyl Oxidase (LOX) ,etc.	Magnetic Luminex Assay for Antigen Detection.
KSC580Hu01	ELISA Kit DIY Materials for Lysyl Oxidase (LOX)	Main materials for "Do It(ELISA Kit) Yourself"