anti- AARS2 antibody

Unlock the secrets of mitochondrial function and translation with our Anti-AARS2 Antibody, available in a 100µg size. AARS2, also known as mitochondrial alanyl-tRNA synthetase 2, is a critical enzyme involved in protein synthesis within mitochondria. Investigating the function of AARS2 is essential for understanding mitochondrial health and its impact on cellular energy production and disease.

Our meticulously crafted antibody specifically targets AARS2 with exceptional specificity and sensitivity, enabling precise detection and quantification in various research applications. Whether you are studying mitochondrial translation, exploring the role of AARS2 in mitochondrial disorders, or investigating its potential as a therapeutic target for mitochondrial diseases, this antibody is an invaluable tool for your research endeavors.

Product Name

AARS2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8.

IMMUNOGEN INFORMATION

Immunogen

alanyl-tRNA synthetase 2, mitochondrial (putative)

Synonyms

AARS2, AARSL, Alanine tRNA ligase, Alanyl tRNA synthetase like, AlaRS, bA444E17.1, KIAA1270, MT ALARS, MTALARS

Observed MW

107 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q5JTZ9

IMAGES

Immunohistochemistry of paraffin-embedded human lung cancer slide using FNab00022( AARS2 Antibody) at dilution of 1:100

K-562 cells were subjected to SDS PAGE followed by western blot with FNab00022(AARS2 antibody) at dilution of 1:1000