anti- ACOX1 antibody

Uncover the mysteries of peroxisomal beta-oxidation with our Anti-ACOX1 Antibody. Available in a generous 100µg size, this antibody empowers you to delve into ACOX1 and its pivotal role in fatty acid metabolism within peroxisomes.

ACOX1, also known as acyl-CoA oxidase 1, is a key enzyme responsible for the initial step of peroxisomal beta-oxidation, a crucial pathway for the breakdown of fatty acids. Our antibody is meticulously crafted to specifically target ACOX1 with remarkable precision and sensitivity. Rigorously validated, it ensures consistent and dependable results, instilling confidence in your exploration of peroxisomal lipid metabolic pathways.

Utilizing state-of-the-art techniques, this antibody is sourced from rabbit hosts, offering a polyclonal clonality that enhances its range of binding capabilities. Its versatility makes it an ideal choice for diverse applications, including Western blotting, immunohistochemistry, and immunofluorescence assays.

Whether you're unraveling fatty acid oxidation mechanisms, studying peroxisome biology, or exploring diseases related to ACOX1 deficiencies, our Anti-ACOX1 Antibody is your trusted research companion. Its high-quality formulation and generous 100µg size ensure it is an indispensable asset for your laboratory, enabling pioneering discoveries and contributions to metabolic research.

Empower your research with the precision and reliability of our Anti-ACOX1 Antibody. Secure your 100µg supply today and embark on a journey of discovery with confidence.

Product Name

ACOX1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.It has 3 isoforms produced by alternative splicing with the molecular mass of 70-74 kDa and can be cleaved post-translationally into a 50-kDa and a 22-kDa subunit between Val468 and Ala469 (PMID: 10672038).

IMMUNOGEN INFORMATION

Immunogen

acyl-Coenzyme A oxidase 1, palmitoyl

Synonyms

ACOX, ACOX1, AOX, PALMCOX, Palmitoyl CoA oxidase, SCOX

Observed MW

74 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:100 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q15067

IMAGES

Immunohistochemistry of paraffin-embedded mouse brain using FNab00095(AOX antibody) at dilution of 1:100

NCI-H460 were subjected to SDS PAGE followed by western blot with FNab00095(AOX antibody) at dilution of 1:1000