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SKU:FNab00345

anti- alpha-synuclein antibody

anti- alpha-synuclein antibody

Regular price $310.00 USD
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Embark on a journey into the world of neurodegenerative diseases and protein aggregation with our highly specialized Anti-Alpha-Synuclein Polyclonal Antibody, now available in a convenient 100µg size. Alpha-synuclein is a key protein implicated in the pathogenesis of Parkinson's disease and other synucleinopathies. This meticulously crafted antibody offers exceptional specificity and sensitivity, making it an ideal choice for a wide range of research applications, from immunohistochemistry to protein-protein interaction studies.

What sets our Anti-Alpha-Synuclein Polyclonal Antibody apart is its outstanding performance. It has undergone rigorous validation and testing to ensure consistent and reproducible results, effectively reducing experimental variability and optimizing resource utilization. With 100µg of antibody, this product provides an ideal balance between cost-effectiveness and practicality, offering ample antibody for multiple experiments while minimizing wastage, aligning with our commitment to sustainable research practices.

Engineered for user-friendliness, our Anti-Alpha-Synuclein Polyclonal Antibody is suitable for researchers of all experience levels, from newcomers to seasoned scientists. It seamlessly integrates into various laboratory techniques, enhancing the precision and reliability of your experiments.

Contribute to a deeper understanding of neurodegenerative processes and protein misfolding with confidence, knowing you have the support of a high-quality, meticulously crafted Anti-Alpha-Synuclein Polyclonal Antibody. Drive advancements in neuroscience research and be part of groundbreaking discoveries in neurodegeneration.

Product Name

alpha-synuclein antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.

IMMUNOGEN INFORMATION

Immunogen

synuclein, alpha (non A4 component of amyloid precursor)

Synonyms

Alpha synuclein, NACP, PARK1, PARK4, SNCA

Observed MW

15 kDa

APPLICATION

Tested Application

ELISA, IHC, WB, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P37840

IMAGES

 

Immunohistochemistry of paraffin-embedded human brain using FNab00345(SNCA antibody) at dilution of 1:50
Immunofluorescent analysis of SH-SY5Y cells using FNab00345 (alpha-synuclein antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)
mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00345(SNCA antibody) at dilution of 1:1000

 

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