anti- AMACR/p504S antibody

Unlock the mysteries of prostate cancer research with our cutting-edge Anti-AMACR/p504S Antibody, now available in a convenient 100µg size. Alpha-methylacyl-CoA racemase (AMACR), also known as p504S, is a valuable biomarker for prostate cancer diagnosis and prognosis. This meticulously crafted antibody offers exceptional specificity and sensitivity, making it an ideal choice for a wide range of research applications, from immunohistochemistry to western blotting.

Our Anti-AMACR/p504S Antibody is characterized by its outstanding performance. It has undergone rigorous validation and testing to ensure consistent and reproducible results, effectively reducing experimental variability and optimizing resource utilization. With 100µg of antibody, this product provides ample material for multiple experiments, striking a balance between cost-effectiveness and practicality.

Designed for ease of use, this antibody accommodates researchers of all experience levels, enhancing the precision and reliability of experiments across various laboratory techniques. Contribute to a deeper understanding of prostate cancer biology and diagnostics with confidence, supported by our high-quality Anti-AMACR/p504S Antibody. Drive advancements in oncology research and be part of groundbreaking discoveries in prostate cancer diagnosis and therapy.

Product Name

AMACR/p504S antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

AMACR(Alpha-methylacyl-CoA racemase) belongs to the CaiB/BaiF CoA-transferase family. It is a mitochondrial and peroxisomal enzyme that catalyzes the conversion of 2R stereoisomers of phytanic and pristanic acid to their S counterparts. AMACR has previously been shown to be a highly sensitive marker for colorectal and clinically localized prostate cancer(PCa). However, AMACR expression is down-regulated at the transcript and protein level in hormone-refractory metastatic PCa, suggesting a hormone-dependent expression of AMACR(PMID:12213712). It has 3 isoforms produced by alternative splicing ang it can form a a dimer of 70-75 kDa(PMID:21812041). Defects in AMACR are the cause of alpha-methylacyl-CoA racemase deficiency(AMACRD) and congenital bile acid synthesis defect type 4(CBAS4).

IMMUNOGEN INFORMATION

Immunogen

alpha-methylacyl-CoA racemase

Synonyms

2 methylacyl CoA racemase, alpha methylacyl CoA racemase, AMACR, CBAS4, p504S, RACE

Observed MW

42 kDa

APPLICATION

Tested Application

ELISA, IHC, WB

Recommended Dilution

WB: 1:500-1:5000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9UHK6

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