anti- AMBRA1 antibody

Embark on a journey into the world of autophagy and cellular homeostasis with our specialized Anti-AMBRA1 Antibody, now available in a 100µg size. AMBRA1, or autophagy and beclin 1 regulator 1, plays a critical role in autophagy induction and regulation. This meticulously crafted antibody offers exceptional specificity and sensitivity, making it an ideal choice for various research applications, from immunoprecipitation to immunofluorescence.

Our Anti-AMBRA1 Antibody stands out for its outstanding performance. It has undergone rigorous validation and testing to ensure consistent and reproducible results, reducing experimental variability. With 100µg of antibody, this product provides ample material for multiple experiments, striking a balance between cost-effectiveness and practicality.

Engineered for user-friendliness, this antibody suits researchers of all experience levels, enhancing the precision and reliability of experiments across various laboratory techniques. Contribute to a deeper understanding of autophagy and cellular homeostasis with confidence, supported by our high-quality Anti-AMBRA1 Antibody. Drive advancements in cell biology research and participate in groundbreaking discoveries in autophagy regulation.

Product Name

AMBRA1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. AMBRA1 (Activating molecule in BECN1-regulated autophagy protein 1), also known as WDR94 or KIAA1736, is a 1, 298 amino acid protein that contains three WD repeats. Localized to cytoplasmic vesicles, AMBRA1 functions to control protein turnover, cell proliferation and cell survival during neuronal development, thereby playing an important role in autophagy and the development of the nervous system. Multiple isoforms of AMBRA1 exist due to alternative spicing events.

IMMUNOGEN INFORMATION

Immunogen

autophagy/beclin-1 regulator 1

Synonyms

AMBRA1, autophagy/beclin 1 regulator 1, FLJ20294, KIAA1736, WDR94

Observed MW

140 kDa

APPLICATION

Tested Application

ELISA, IHC, WB

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q9C0C7

IMAGES