anti- Amphiphysin antibody

Unlock the mysteries of synaptic vesicle endocytosis and neuronal function with our highly specific Anti-Amphiphysin Antibody, available in a convenient 100µg size. Amphiphysin is a critical player in the molecular machinery that mediates synaptic vesicle recycling and influences neurotransmission, making it a vital target for researchers studying synaptic plasticity and neurological disorders.

Our meticulously crafted Anti-Amphiphysin Antibody offers exceptional specificity and sensitivity in various research applications, from immunofluorescence to co-immunoprecipitation studies. It has undergone rigorous validation to ensure consistent and reproducible results, effectively reducing experimental variability and optimizing resource utilization.

With 100µg of high-quality antibody, this product provides ample material for multiple experiments, striking a balance between cost-effectiveness and practicality. Designed for ease of use, it accommodates researchers of all experience levels, enhancing the precision and reliability of experiments across various laboratory techniques.

Contribute to a deeper understanding of synaptic vesicle dynamics, neurotransmission, and neuronal function with confidence, supported by our high-quality Anti-Amphiphysin Antibody. Drive advancements in neurobiology research and be part of groundbreaking discoveries in synaptic physiology.

Product Name

Amphiphysin antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Amphiphysin(AMPH), a synaptic vesicle-associated protein that is highly concentrated in nerve terminal, is an autoantigen of Stiff-Man syndrome with breast cancer. Amphiphysin contains a N-terminal BAR(Bin1/Amphiphysin/Rv167) domain followed by an endocytosis domain, and a C-terminal SH3 domain. Amphiphysin has been proposed to function as a linker between the clathrin coat and dynamin in the endocytosis of synaptic vesicles. It may also participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types.

IMMUNOGEN INFORMATION

Immunogen

amphiphysin

Synonyms

Amphiphysin,AMPH1,AMPH

Observed MW

120 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IP

Recommended Dilution

WB: 1:500-1:5000; IHC: 1:20-1:200; IP: 1:500-1:5000

UNIPROT INFORMATION

UniProt ID

P49418

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