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FineTest

SKU:FNab00378

anti- AMPK beta 2 antibody

anti- AMPK beta 2 antibody

Regular price $290.00 USD
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Embark on a journey into the intricate world of cellular energy regulation with our specialized Anti-AMPK Beta 2 Antibody, now available in a 100µg size. AMP-activated protein kinase (AMPK) is a key player in cellular energy sensing, making it a valuable target for researchers exploring metabolic disorders and signaling pathways.

Our meticulously crafted Anti-AMPK Beta 2 Antibody offers exceptional specificity and sensitivity, making it a versatile tool for various research applications, from immunohistochemistry to co-immunoprecipitation studies. It has undergone rigorous validation to ensure consistent and reproducible results, effectively minimizing experimental variability and optimizing resource utilization.

With 100µg of high-quality antibody, this product provides ample material for multiple experiments, striking a balance between cost-effectiveness and practicality. Engineered for user-friendliness, it accommodates researchers of all experience levels, enhancing the accuracy and dependability of experiments across various laboratory techniques.

Contribute to a deeper understanding of metabolic disorders, cellular signaling, and energy metabolism with confidence, supported by our high-quality Anti-AMPK Beta 2 Antibody. Drive advancements in molecular and cellular biology research and be part of groundbreaking discoveries in cellular energy regulation.

Product Name

AMPK beta 2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

protein kinase, AMP-activated, beta 2 non-catalytic subunit

Synonyms

AMPK beta 2, AMPK subunit beta 2, PRKAB2

Observed MW

35 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

O43741

IMAGES

 

Immunohistochemistry of paraffin-embedded rat kidney using FNab00378(PRKAB2 antibody) at dilution of 1:100
human brain tissue were subjected to SDS PAGE followed by western blot with FNab00378(PRKAB2 antibody) at dilution of 1:1000

 

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