anti- ANAPC5 antibody

Explore the intricate world of cell cycle regulation and mitotic control with our specialized Anti-ANAPC5 Antibody, now available in a 100µg size. ANAPC5, a critical component of the anaphase-promoting complex/cyclosome (APC/C), is a central target for researchers investigating cell division and related processes.

Our Anti-ANAPC5 Antibody is rigorously designed to provide exceptional specificity and sensitivity, making it suitable for various research applications, from Western blotting to immunofluorescence. Rigorous validation ensures consistent and reproducible results, effectively reducing experimental variability and optimizing resource utilization.

With 100µg of high-quality antibody, this product offers ample material for multiple experiments, maintaining cost-effectiveness while ensuring research reliability. Its user-friendly design accommodates researchers of all experience levels, enhancing the accuracy and dependability of experiments across diverse laboratory techniques.

Contribute to a deeper understanding of cell cycle regulation, mitosis, and related fields with confidence, supported by our high-quality Anti-ANAPC5 Antibody. Drive advancements in cell biology research and be part of innovative discoveries in cell division control.

Product Name

ANAPC5 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.

IMMUNOGEN INFORMATION

Immunogen

anaphase promoting complex subunit 5

Synonyms

ANAPC5, APC5, Cyclosome subunit 5

Observed MW

85 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q9UJX4

IMAGES