anti- androgen receptor antibody

Dive deep into the intricate world of hormone signaling and androgen receptor biology with our Polyclonal Anti-Androgen Receptor Antibody, now available in a convenient 100µg size. The androgen receptor, a pivotal player in mediating the effects of androgens, is central to research on hormone-related diseases and therapeutic interventions.

Our Polyclonal Anti-Androgen Receptor Antibody is meticulously developed to offer exceptional specificity and sensitivity, making it an ideal choice for various research applications. From immunohistochemistry to ChIP assays, this antibody delivers consistent and reproducible results, effectively reducing experimental variability and enhancing research efficiency.

With 100µg of high-quality antibody, this product provides sufficient material for multiple experiments, ensuring cost-effectiveness without compromising quality. Its user-friendly design caters to researchers of all experience levels, facilitating precise and reliable experiments across a range of laboratory techniques.

Contribute to a deeper understanding of hormone signaling, androgen receptor function, and related diseases with confidence, supported by our Polyclonal Anti-Androgen Receptor Antibody. Drive advancements in endocrinology research and contribute to groundbreaking discoveries in hormone regulation.

Product Name

androgen receptor antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (SBMA, also known as Kennedy's disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Alternative splicing results in multiple transcript variants encoding different isoforms.

IMMUNOGEN INFORMATION

Immunogen

androgen receptor

Synonyms

AIS, androgen receptor, AR, DHTR, Dihydrotestosterone receptor, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM

Observed MW

100 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

P10275

IMAGES